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المؤلفون: Xing Zhang, Robert Blumenthal, John R. Horton, Jujun Zhou, Xiaodong Cheng
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, DNA, Bacterial, Models, Molecular, Site-Specific DNA-Methyltransferase (Adenine-Specific), Methyltransferase, Stereochemistry, Base pair, Science, 030106 microbiology, Coenzymes, General Physics and Astronomy, Genome, General Biochemistry, Genetics and Molecular Biology, Article, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Recognition sequence, Clostridioides, Species Specificity, Nucleotide Motifs, Base Pairing, X-ray crystallography, Bacterial structural biology, Multidisciplinary, biology, Base Sequence, Chemistry, Adenine, General Chemistry, Methylation, biology.organism_classification, S-Adenosylhomocysteine, Restriction enzyme, 030104 developmental biology, Enzyme mechanisms, Nucleic Acid Conformation, Bacteria, DNA
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المؤلفون: Olafur S. Indridason, Vidar O. Edvardsson, Sigurjon A. Gudjonsson, Gudny A. Arnadottir, John A. Sayer, Patrick Sulem, Hrafnhildur Linnet Runolfsdottir, Hildigunnur Katrinardottir, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Runolfur Palsson, Run Fridriksdottir, Kari Stefansson, Brynjar O. Jensson
المصدر: European Journal of Human Genetics
مصطلحات موضوعية: 0301 basic medicine, Genotype, Population, Adenine Phosphoribosyltransferase, Adenine phosphoribosyltransferase deficiency, Human genetic variation, Biology, Article, 03 medical and health sciences, Medical research, 0302 clinical medicine, Gene Frequency, Urolithiasis, Databases, Genetic, Genetics, medicine, Humans, Missense mutation, Genetic Predisposition to Disease, Registries, education, Allele frequency, Alleles, Genetic Association Studies, Genetics (clinical), education.field_of_study, Genomics, medicine.disease, Minor allele frequency, 030104 developmental biology, Amino Acid Substitution, Population Surveillance, Mutation, Metabolism, Inborn Errors, 030217 neurology & neurosurgery, Founder effect
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المؤلفون: Tadashi Nakai, Kazuo Kobayashi, Toshinori Oozeki, Kazuki Kozakai, Toshihide Okajima, Katsuyuki Tanizawa, Kazuki Okamoto, Shun'ichi Kuroda
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Science, Coenzymes, General Physics and Astronomy, Flavoprotein, Catalysis, Article, General Biochemistry, Genetics and Molecular Biology, Cofactor, Mixed Function Oxygenases, 03 medical and health sciences, chemistry.chemical_compound, Bacterial Proteins, Indolequinones, Ternary complex, Paracoccus denitrificans, X-ray crystallography, chemistry.chemical_classification, Flavin adenine dinucleotide, Multidisciplinary, Flavoproteins, 030102 biochemistry & molecular biology, biology, Tryptophan, Substrate (chemistry), Dipeptides, General Chemistry, Amino acid, enzymes and coenzymes (carbohydrates), 030104 developmental biology, chemistry, Dihydroxylation, Enzyme mechanisms, Flavin-Adenine Dinucleotide, biology.protein, Oxidoreductases
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المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani
المصدر: Journal of Advanced Research
مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies
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المؤلفون: Zhi-Yuan Wu, Jin-Song Bian, Xiao-Wei Nie, Hai-Jian Sun, Xin-Yu Wang
المصدر: Journal of Advanced Research, Vol 27, Iss, Pp 127-135 (2021)
Journal of Advanced Researchمصطلحات موضوعية: 0301 basic medicine, Steatosis, STAT3, signal transducer and activator of transcription 3, Regulator, HO-1, heme oxygenase 1, SPRC, S-propargyl-cysteine, NaHS, sodium hydrosulfide, Liver disease, 0302 clinical medicine, HFD, high fat diet, PPG, propargylglycine, Fibrosis, MMP-2, matrix metalloproteinase 2, NF-κB, nuclear factor-kappa B, Cancer, lcsh:R5-920, Multidisciplinary, Hydrogen sulfide, CAT, cysteine aminotransferase, PI3K, phosphatidylinositol 3-kinase, CBS, cystathione β-synthase, FAS, fatty acid synthase, CSE, cystathione γ-lyase, DAO, D-amino acid oxidase, CO, carbon monoxide, COX-2, cyclooxygenase-2, 030220 oncology & carcinogenesis, NAFLD, non-alcoholic fatty liver diseases, AGTR1, angiotensin II type 1 receptor, CX3CR1, chemokine CX3C motif receptor 1, lcsh:Medicine (General), Liver cancer, NASH, nonalcoholic steatohepatitis, Nrf2, nuclear factor erythroid2-related factor 2, 3-MST, 3-mercaptopyruvate sulfurtransferase, Sulfurtransferase, mTOR, mammalian target of rapamycin, Article, SAC, S-allyl-cysteine, H2S, hydrogen sulfide, 03 medical and health sciences, VLDL, very low density lipoprotein, NADH, nicotinamide adenine dinucleotide, medicine, lcsh:Science (General), ComputingMethodologies_COMPUTERGRAPHICS, PTEN, phosphatase and tensin homolog deleted on chromosome ten, 3-MP, 3-mercaptopyruvate, business.industry, ERK, extracellular regulated protein kinases, IR, ischemia/reperfusion, NADPH, nicotinamide adenine dinucleotide phosphate, equipment and supplies, medicine.disease, EGFR, epidermal growth factor receptor, AMPK, AMP-activated protein kinase, 030104 developmental biology, Akt, protein kinase B, Cancer research, DATS, Diallyl trisulfide, PLP, pyridoxal 5′-phosphate, Hepatic fibrosis, business, lcsh:Q1-390
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المؤلفون: Trong Thuan Ung, Shinan Li, Thi Thinh Nguyen, Young Do Jung, Jae-Young Han
المصدر: Toxicology Letters. 349:155-164
مصطلحات موضوعية: 0301 basic medicine, Nicotine, Carcinoma, Hepatocellular, Toxicology, p38 Mitogen-Activated Protein Kinases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Basic Helix-Loop-Helix Transcription Factors, Cytochrome P-450 CYP1A1, polycyclic compounds, medicine, Humans, heterocyclic compounds, Nicotinic Agonists, Protein kinase A, Protein kinase B, Cell Proliferation, Oxidase test, NADPH oxidase, biology, Liver Neoplasms, Transcription Factor RelA, Hep G2 Cells, General Medicine, respiratory system, Aryl hydrocarbon receptor, Molecular biology, Transcription Factor AP-1, 030104 developmental biology, Receptors, Aryl Hydrocarbon, chemistry, Enzyme Induction, biology.protein, Signal transduction, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Nicotinamide adenine dinucleotide phosphate, Signal Transduction, medicine.drug
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المؤلفون: Yiqing Zheng, Yongyi Ye, Haidi Yang, Ting Zhan, Wuhui He, Xin Min, Xiaotong Huang, Jiaqi Pang, Hao Xiong, Weijian Zhang, Feinan He, Zhengrong Liang, Bingquan Jian, Yiming Gao
المصدر: Toxicology Letters. 349:115-123
مصطلحات موضوعية: 0301 basic medicine, Cisplatin, biology, AMPK, General Medicine, Nicotinamide adenine dinucleotide, Pharmacology, Toxicology, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, PARP1, medicine.anatomical_structure, chemistry, Ototoxicity, Sirtuin, medicine, biology.protein, NAD+ kinase, Hair cell, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: James M Dominguez, Sharon M. Moe, Neal X. Chen, Kalisha D. O'Neill
المصدر: Vascular Medicine. 26:585-594
مصطلحات موضوعية: 0301 basic medicine, Cell signaling, Vascular smooth muscle, Myocytes, Smooth Muscle, 030204 cardiovascular system & hematology, Mitochondrion, medicine.disease_cause, Endocytosis, Muscle, Smooth, Vascular, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Animals, Humans, Medicine, Vascular Calcification, Cells, Cultured, chemistry.chemical_classification, Reactive oxygen species, business.industry, Rats, Cell biology, 030104 developmental biology, chemistry, NOX1, Reactive Oxygen Species, Cardiology and Cardiovascular Medicine, business, Oxidative stress, Nicotinamide adenine dinucleotide phosphate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2e5dfbcb1fa4bbfc7a2a2db995231d3
https://doi.org/10.1177/1358863x211024721 -
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المؤلفون: Lakmini Mudduwa, Kamani Ayoma Perera Wijewardana Jayatilaka, Jayasinghe Arachchige Nirosha Sandamali, Ruwani Punyakanthi Hewawasam
المصدر: Saudi Pharmaceutical Journal, Vol 29, Iss 8, Pp 820-832 (2021)
Saudi Pharmaceutical Journal : SPJمصطلحات موضوعية: 0301 basic medicine, Glutathione reductase, Pharmaceutical Science, Pharmacology, medicine.disease_cause, SOD, Superoxide dismutase, Lipid peroxidation, DNA, Deoxyribonucleic acid, chemistry.chemical_compound, 0302 clinical medicine, ABTS, 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), GR, Glutathione reductase, USA, United States of America, DPPH, 2,2-diphenyl-1-picrylhydrazyl, chemistry.chemical_classification, Cinnamomum zeylanicum Bark Extract, cTnI, Cardiac troponin I, Myeloperoxidase, biology, NT-pro BNP, N terminal- pro brain natriuretic peptide, Glutathione peroxidase, Antioxidant effect, Cinnamomum zeylanicum, FRAP, Ferric reducing antioxidant power, IP, Intraperitoneal, ELISA, Enzyme-linked immunosorbent assay, 030220 oncology & carcinogenesis, GPx, Glutathione peroxidase, Original Article, H & E, Haematoxylin and eosin, AST, Aspartate aminotransferase, MPO, Myeloperoxidase, PBS, Phosphate buffered saline, RM1-950, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, NO, Nitric oxide, WHO, World Health Organization, Cinnamomum zeylanicum bark extract, GSH, Reduced glutathione, 03 medical and health sciences, medicine, MDA, Malondialdehyde, LDH, Lactate dehydrogenase, ABEC, Aqueous bark extract of Cinnamomum zeylanicum, Glutathione, biology.organism_classification, Cardiotoxicity, Oxidative-stress, 030104 developmental biology, chemistry, Doxorubicin, Therapeutics. Pharmacology, Oxidative stress, ROS, Reactive oxygen species, Cinnamomum
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المؤلفون: Yifei Zhu, Jing Han, Chun-Lei Tang, Xin Ma, Wang Xiao, Liangliang Liu, Mengru Gao
المصدر: Journal of Molecular and Cellular Cardiology. 157:66-76
مصطلحات موضوعية: 0301 basic medicine, TRPV4, Mice, Obese, TRPV Cation Channels, Inflammation, Vasodilation, 030204 cardiovascular system & hematology, Pharmacology, medicine.disease_cause, Nitric oxide, Mice, 03 medical and health sciences, chemistry.chemical_compound, Transient receptor potential channel, 0302 clinical medicine, medicine, Animals, Obesity, Molecular Biology, Mice, Knockout, chemistry.chemical_classification, Reactive oxygen species, Endothelial Cells, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, chemistry, Mutation, NADPH Oxidase 2, Disease Susceptibility, Endothelium, Vascular, Inflammation Mediators, medicine.symptom, Reactive Oxygen Species, Cardiology and Cardiovascular Medicine, Biomarkers, Nicotinamide adenine dinucleotide phosphate, Oxidative stress, Protein Binding