المؤلفون: Li XW; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ran JH; Department of Anatomy, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China., Zhou H; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., He JZ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Qiu ZW; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Wang SY; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Wu MN; Department of Anatomy, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China., Zhu S; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., An YP; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ma A; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Li M; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Quan YZ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Li NN; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ren CQ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Yang BX; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. baoxue@bjmu.edu.cn.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, 100191, China. baoxue@bjmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2023 Feb; Vol. 44 (2), pp. 406-420. Date of Electronic Publication: 2022 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Kidney, Autosomal Dominant*/drug therapy , Polycystic Kidney, Autosomal Dominant*/metabolism , Polycystic Kidney, Autosomal Dominant*/pathology , Cysts*/metabolism , Cysts*/pathology, Mice ; Animals ; Cilia ; Tubulin/metabolism ; Hedgehog Proteins/metabolism ; Kidney/pathology ; Mice, Knockout ; TRPP Cation Channels/metabolism ; Epithelial Cells/metabolism