المؤلفون: Peng LL; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.; Department of Pharmacy, General Hospital of Guangzhou Military Command of PLA, Guangzhou 510110, China., Zhao YQ; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China., Zhou ZY; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China., Jin J; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zhao M; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China., Chen XM; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Chen LY; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Cai YF; Department of Neurology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China., Li JL; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Huang M; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2016 Nov; Vol. 37 (11), pp. 1442-1448. Date of Electronic Publication: 2016 Sep 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: 1-Alkyl-2-acetylglycerophosphocholine Esterase/*genetics , Aspirin/*therapeutic use , Blood Platelets/*drug effects , Brain Ischemia/*drug therapy , Platelet Aggregation Inhibitors/*therapeutic use , Receptors, Cell Surface/*genetics , Receptors, Thromboxane A2, Prostaglandin H2/*genetics , Stroke/*drug therapy, ATP Binding Cassette Transporter, Subfamily B/genetics ; Aged ; Asian People ; Brain Ischemia/blood ; Brain Ischemia/genetics ; Female ; Gene Frequency ; Genetic Association Studies ; Humans ; Linkage Disequilibrium ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Stroke/blood ; Stroke/genetics ; Thromboxane B2/biosynthesis ; Thromboxane B2/blood ; Treatment Failure

المؤلفون: Liu R; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zhou ZY; Guangdong Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China., Chen YB; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Li JL; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Yu WB; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Chen XM; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zhao M; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Zhao YQ; Guangdong Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China., Cai YF; Guangdong Provincial Hospital of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China., Jin J; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China., Huang M; Institute of Clinical Pharmacology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2016 Jul; Vol. 37 (7), pp. 882-8. Date of Electronic Publication: 2016 May 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Cytochrome P-450 CYP2C19/*genetics , Cytochrome P-450 CYP3A/*genetics , Drug Resistance/*genetics , Receptors, Purinergic P2Y12/*genetics , Receptors, Steroid/*genetics , Ticlopidine/*analogs & derivatives, Aged ; Asian People/genetics ; Case-Control Studies ; Clopidogrel ; Female ; Genetic Association Studies ; Genotype ; Humans ; Hypertension/genetics ; Male ; Platelet Aggregation/drug effects ; Platelet Aggregation Inhibitors ; Polymorphism, Single Nucleotide ; Pregnane X Receptor ; Protective Factors ; Risk Factors ; Stroke/drug therapy ; Stroke/genetics ; Ticlopidine/pharmacology ; Ticlopidine/therapeutic use