المؤلفون: Liu HH; Out-patient Department of Day Diagnosis and Treatment, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China., Xie Y; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China.; Chinese PLA Medical School, Chinese PLA General Hospital, Beijing, 100039, China., Yang BP; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Wen HY; Hunyuan County People's Hospital, Datong, 037499, Shanxi Province, China., Yang PH; Faculty of Hepato-Pancreato-Biliary Surgery, Institute of Hepatobiliary Surgery, The First Medical Center, Chinese PLA General Hospital, Beijing, 100853, China., Lu JE; Hunyuan County People's Hospital, Datong, 037499, Shanxi Province, China., Liu Y; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Chen X; Out-patient Department of Day Diagnosis and Treatment, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100039, China., Qu MM; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Zhang Y; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Hong WG; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Li YG; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China., Fu J; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China. fjunliang@163.com.; Chinese PLA Medical School, Chinese PLA General Hospital, Beijing, 100039, China. fjunliang@163.com., Wang FS; Senior Department of Infectious Diseases, The Fifth Medical Center of Chinese PLA General Hospital, National Clinical Research Center for Infectious Diseases, Beijing, 100039, China. fswang302@163.com.; Chinese PLA Medical School, Chinese PLA General Hospital, Beijing, 100039, China. fswang302@163.com.

المصدر: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2024 May 13; Vol. 9 (1), pp. 129. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*/prevention & control , COVID-19*/immunology , COVID-19 Vaccines*/immunology , COVID-19 Vaccines*/adverse effects , COVID-19 Vaccines*/administration & dosage , SARS-CoV-2*/immunology , Antibodies, Viral*/immunology , Antibodies, Viral*/blood , Vaccines, Inactivated*/immunology , Vaccines, Inactivated*/adverse effects , Vaccines, Inactivated*/administration & dosage , Antibodies, Neutralizing*/immunology , Antibodies, Neutralizing*/blood, Humans ; Female ; Male ; Aged ; Prospective Studies ; Aged, 80 and over ; Adult ; Vaccination ; Longitudinal Studies ; Middle Aged ; Vaccines, Synthetic/immunology ; Vaccines, Synthetic/adverse effects ; Vaccines, Synthetic/administration & dosage ; Immunogenicity, Vaccine/immunology ; Immunization, Secondary

المؤلفون: Sun L; Personalized Drug Therapy Key Laboratory of Sichuan Province, Department of Pharmacy, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China.; School of Life Sciences, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment in Special Environment, Northwestern Polytechnical University, Xi'an, 710072, China., Liu H; Personalized Drug Therapy Key Laboratory of Sichuan Province, Department of Pharmacy, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China., Ye Y; Sorrento Therapeutics Inc., 4955 Directors Place, San Diego, CA, 92121, USA., Lei Y; School of Life Sciences, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment in Special Environment, Northwestern Polytechnical University, Xi'an, 710072, China., Islam R; School of Life Sciences, Engineering Research Center of Chinese Ministry of Education for Biological Diagnosis, Treatment and Protection Technology and Equipment in Special Environment, Northwestern Polytechnical University, Xi'an, 710072, China., Tan S; Personalized Drug Therapy Key Laboratory of Sichuan Province, Department of Pharmacy, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China., Tong R; Personalized Drug Therapy Key Laboratory of Sichuan Province, Department of Pharmacy, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China., Miao YB; Department of Haematology, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China. miaoyangbao@gmail.com., Cai L; Personalized Drug Therapy Key Laboratory of Sichuan Province, Department of Pharmacy, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China. cailulu@med.uestc.edu.cn.

المصدر: Signal transduction and targeted therapy [Signal Transduct Target Ther] 2023 Nov 03; Vol. 8 (1), pp. 418. Date of Electronic Publication: 2023 Nov 03.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE

مواضيع طبية MeSH: Nanotubes, Carbon* , Metal Nanoparticles* , Neoplasms*/drug therapy , Neoplasms*/pathology, Humans ; Gold/therapeutic use ; Artificial Intelligence ; Peptides

المؤلفون: Zhang Y; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang YY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Pan ZW; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li QQ; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Sun LH; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li X; Department of Cardiovascular Sciences, School of Engineering, University of Leicester, Leicester, UK., Gong MY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Yang XW; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Wang YY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li HD; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Xuan LN; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Shao YC; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li MM; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang MY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Yu Q; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li Z; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang XF; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu DH; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhu YM; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Tan ZY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang YY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu YQ; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang Y; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Jiao L; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. jiaolei116@163.com., Yang BF; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Medicine Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn.; Department of Pharmacology and Therapeutics, Melbourne School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, VIC, Australia. yangbf@ems.hrbmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2023 May; Vol. 44 (5), pp. 999-1013. Date of Electronic Publication: 2022 Nov 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/metabolism , Endothelial Progenitor Cells*/metabolism , Endothelial Progenitor Cells*/pathology , Growth Differentiation Factors*/therapeutic use , Growth Differentiation Factors*/metabolism , Wound Healing*/drug effects, Animals ; Humans ; Mice ; Bone Morphogenetic Proteins/metabolism ; Chemokine CXCL12/drug effects ; Chemokine CXCL12/metabolism ; Diabetes Mellitus, Type 2/drug therapy ; Diabetes Mellitus, Type 2/metabolism ; Neovascularization, Physiologic ; Vascular Endothelial Growth Factor A/drug effects ; Vascular Endothelial Growth Factor A/metabolism ; Recombinant Proteins/metabolism ; Recombinant Proteins/therapeutic use ; Hypoxia-Inducible Factor 1, alpha Subunit/drug effects ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism

المؤلفون: Li XW; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ran JH; Department of Anatomy, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China., Zhou H; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., He JZ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Qiu ZW; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Wang SY; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Wu MN; Department of Anatomy, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, China., Zhu S; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., An YP; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ma A; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Li M; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Quan YZ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Li NN; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ren CQ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Yang BX; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. baoxue@bjmu.edu.cn.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, 100191, China. baoxue@bjmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2023 Feb; Vol. 44 (2), pp. 406-420. Date of Electronic Publication: 2022 Jul 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Kidney, Autosomal Dominant*/drug therapy , Polycystic Kidney, Autosomal Dominant*/metabolism , Polycystic Kidney, Autosomal Dominant*/pathology , Cysts*/metabolism , Cysts*/pathology, Mice ; Animals ; Cilia ; Tubulin/metabolism ; Hedgehog Proteins/metabolism ; Kidney/pathology ; Mice, Knockout ; TRPP Cation Channels/metabolism ; Epithelial Cells/metabolism

المؤلفون: Dong Q; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA., Yao Y; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA., Cheng S; Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD, USA., Alexopoulos K; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA.; Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA., Gao J; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA., Srinivas S; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA., Wang Y; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA., Pei Y; Department of Mechanical Engineering, University of Maryland, College Park, MD, USA., Zheng C; Department of Mechanical Engineering, University of Maryland, College Park, MD, USA., Brozena AH; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA., Zhao H; Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, USA., Wang X; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA., Toraman HE; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA.; Department of Energy and Mineral Engineering, The Pennsylvania State University, University Park, PA, USA., Yang B; Department of Mechanical Engineering, University of Maryland, College Park, MD, USA., Kevrekidis IG; Department of Chemical and Biomolecular Engineering, Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA., Ju Y; Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, USA., Vlachos DG; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE, USA. vlachos@udel.edu., Liu D; Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD, USA. liud@umd.edu., Hu L; Department of Materials Science and Engineering, University of Maryland, College Park, MD, USA. binghu@umd.edu.; Center for Materials Innovation, University of Maryland, College Park, MD, USA. binghu@umd.edu.

المصدر: Nature [Nature] 2022 May; Vol. 605 (7910), pp. 470-476. Date of Electronic Publication: 2022 May 18.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Li HM; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu X; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Meng ZY; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Wang L; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhao LM; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Chen H; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Wang ZX; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Cui H; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Tang XQ; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Li XH; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Han WN; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Bai X; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Lin Y; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Liu H; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China., Zhang Y; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. hmuzhangyong@hotmail.com.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone, Chinese Academy of Medical Sciences, Harbin, 150086, China. hmuzhangyong@hotmail.com.; Institute of Metabolic Disease, Heilongjiang Academy of Medical Science, Harbin, 150086, China. hmuzhangyong@hotmail.com., Yang BF; Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone, Chinese Academy of Medical Sciences, Harbin, 150086, China. yangbf@ems.hrbmu.edu.cn.; Department of Pharmacology and Therapeutics, Melbourne School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences University of Melbourne, Melbourne, Australia. yangbf@ems.hrbmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2022 Mar; Vol. 43 (3), pp. 613-623. Date of Electronic Publication: 2021 May 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Aging/*drug effects , Anthraquinones/*pharmacology , Emodin/*pharmacology , Heart Diseases/*pathology , Mitophagy/*drug effects, Animals ; Benzofurans ; Disease Models, Animal ; Female ; Galactose/pharmacology ; Mice ; Molecular Docking Simulation ; Myocytes, Cardiac/drug effects ; Quinolines ; Random Allocation ; Ubiquitin-Protein Ligases/drug effects

المؤلفون: Xue GL; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Li DS; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Wang ZY; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Liu Y; Department of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, 150001, China., Yang JM; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Li CZ; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Li XD; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Ma JD; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Zhang MM; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Lu YJ; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China., Li Y; Department of Cardiology, The First Affiliated Hospital, Harbin Medical University, Harbin, 150001, China., Yang BF; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China. yangbf@ems.hrbmu.edu.cn., Pan ZW; Department of Pharmacology (The Key Laboratory of Cardiovascular Research, Ministry of Education) at College of Pharmacy, Harbin Medical University, Harbin, 150086, China. panzw@ems.hrbmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Nov; Vol. 42 (11), pp. 1780-1789. Date of Electronic Publication: 2021 Feb 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Channels, L-Type/*biosynthesis , Heart Failure/*metabolism , Interleukin-17/*biosynthesis , NF-kappa B/*biosynthesis , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*biosynthesis , Up-Regulation/*physiology, Animals ; Animals, Newborn ; Calcium Channels, L-Type/genetics ; Cell Line ; Cells, Cultured ; Gene Expression ; Heart Failure/genetics ; Heart Failure/pathology ; Humans ; Interleukin-17/deficiency ; Interleukin-17/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; NF-kappa B/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics

المؤلفون: Abulizi A; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Hu L; Department of Anatomy and Laboratory of Neuroscience and Tissue Engineering, Basic Medical College, Chongqing Medical University, Chongqing, 400016, China., Ma A; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Shao FY; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Zhu HZ; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Lin SM; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Shao GY; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Xu Y; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Ran JH; Stem Cell and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, 400016, China., Li J; Stem Cell and Tissue Engineering, Department of Histology and Embryology, Chongqing Medical University, Chongqing, 400016, China., Zhou H; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China., Lin DM; JUNCAO Technology Research Institute, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Wang LF; JUNCAO Technology Research Institute, Fujian Agriculture and Forestry University, Fuzhou, 350002, China., Li M; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. leemin@bjmu.edu.cn., Yang BX; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. baoxue@bjmu.edu.cn.; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, 100191, China. baoxue@bjmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Oct; Vol. 42 (10), pp. 1703-1713. Date of Electronic Publication: 2021 Apr 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Colonic Neoplasms/*drug therapy , Muscle Fatigue/*drug effects , Triterpenes/*therapeutic use, Animals ; Cell Line, Tumor ; Colonic Neoplasms/pathology ; Cytokines/metabolism ; Energy Metabolism/drug effects ; Female ; Fluorouracil/adverse effects ; Fluorouracil/therapeutic use ; Hippocampus/drug effects ; Hippocampus/metabolism ; Mice, Inbred BALB C ; Muscle, Skeletal/drug effects ; Muscle, Skeletal/pathology ; Mice

المؤلفون: Zhang L; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Wang YN; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Ju JM; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Shabanova A; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China.; Department of Outpatient and Emergency Pediatric, Bashkir State Medical University, Ground Floor, Teatralnaya Street, 2a, 450000, Ufa, Russia., Li Y; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Fang RN; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Sun JB; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Guo YY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Jin TZ; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Liu YY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Li TY; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China., Shan HL; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China., Liang HH; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. lianghaihai@ems.hrbmu.edu.cn.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China. lianghaihai@ems.hrbmu.edu.cn.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China. lianghaihai@ems.hrbmu.edu.cn., Yang BF; Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education), College of Pharmacy, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn.; Northern Translational Medicine Research and Cooperation Center, Heilongjiang Academy of Medical Sciences, Harbin Medical University, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China. yangbf@ems.hrbmu.edu.cn.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 May; Vol. 42 (5), pp. 691-700. Date of Electronic Publication: 2020 Aug 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Inflammation/*metabolism , Mitochondria/*metabolism , Molecular Chaperones/*metabolism , Myocardial Infarction/*metabolism, Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Down-Regulation ; Heart/drug effects ; Hydrogen Peroxide/pharmacology ; Macrophages/metabolism ; Male ; Mice, Inbred C57BL ; Myocardium/metabolism ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Reactive Oxygen Species/metabolism ; Mice

المؤلفون: Li F; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Li J; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Yin K; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Zhang J; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Li ZH; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Lu L; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Bao YW; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Qin Z; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China., Zheng Y; Wuxi Biologics Co. Ltd, Wuxi, 214092, China., Yang BT; Wuxi Biologics Co. Ltd, Wuxi, 214092, China., Li J; Wuxi Biologics Co. Ltd, Wuxi, 214092, China., Wang X; CStone Pharmaceuticals (Suzhou) Co., Ltd, Shanghai, 201203, China. wangxinzhong@cstonepharma.com.

المصدر: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2021 Jan; Vol. 42 (1), pp. 142-148. Date of Electronic Publication: 2020 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal, Humanized/*therapeutic use , Antineoplastic Agents, Immunological/*therapeutic use , Colonic Neoplasms/*therapy , Programmed Cell Death 1 Receptor/*immunology, Animals ; Antibodies, Monoclonal, Humanized/immunology ; Antibodies, Monoclonal, Humanized/pharmacokinetics ; Antineoplastic Agents, Immunological/immunology ; Antineoplastic Agents, Immunological/pharmacokinetics ; B7-H1 Antigen/metabolism ; Cell Proliferation/drug effects ; Cross Reactions ; Female ; Gene Knock-In Techniques ; Humans ; Immunotherapy ; Interferon-gamma/metabolism ; Interleukin-2/metabolism ; Macaca fascicularis ; Male ; Mice, Inbred C57BL ; Programmed Cell Death 1 Receptor/genetics ; Programmed Cell Death 1 Receptor/metabolism ; Protein Binding/drug effects ; T-Lymphocytes/drug effects ; Mice