المؤلفون: Maiorino M; 1 Department of Molecular Medicine, University of Padova , Padova, Italy ., Conrad M; 2 Institute of Developmental Genetics , Helmholtz Zentrum München, Neuherberg, Germany ., Ursini F; 1 Department of Molecular Medicine, University of Padova , Padova, Italy .

المصدر: Antioxidants & redox signaling [Antioxid Redox Signal] 2018 Jul 01; Vol. 29 (1), pp. 61-74. Date of Electronic Publication: 2017 May 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

مواضيع طبية MeSH: Cell Death*/drug effects , Lipid Peroxidation*/drug effects, Glutathione Peroxidase/*metabolism, Animals ; Glutathione Peroxidase/antagonists & inhibitors ; Humans ; Iron Chelating Agents/pharmacology ; Phospholipid Hydroperoxide Glutathione Peroxidase ; alpha-Tocopherol/pharmacology

المؤلفون: Ingold I; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Berndt C; Heinrich-Heine University, Department of Neurology, Medical Faculty, 40255 Düsseldorf, Germany., Schmitt S; Institute of Toxicology and Environmental Hygiene, Technical University of Munich, 80802 Munich, Germany., Doll S; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Poschmann G; Heinrich-Heine University, Molecular Proteomics Laboratory, Biomedical Research Center (BMFZ), 40225 Düsseldorf, Germany., Buday K; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Roveri A; Department of Molecular Medicine, University of Padova, Padova, Italy., Peng X; CVMD Translational Medicine Unit, Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden., Porto Freitas F; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Seibt T; Department of Nephrology, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, 80336 München, Germany., Mehr L; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Aichler M; Helmholtz Zentrum München, Research Unit of Analytical Pathology, 85764 Neuherberg, Germany., Walch A; Helmholtz Zentrum München, Research Unit of Analytical Pathology, 85764 Neuherberg, Germany., Lamp D; Helmholtz Zentrum München, Helmholtz Diabetes Center and German Diabetes Center (DZD), 85764 Neuherberg, Germany; Helmholtz Zentrum München, Institute for Diabetes and Obesity, 85748 Garching, Germany., Jastroch M; Helmholtz Zentrum München, Helmholtz Diabetes Center and German Diabetes Center (DZD), 85764 Neuherberg, Germany; Helmholtz Zentrum München, Institute for Diabetes and Obesity, 85748 Garching, Germany., Miyamoto S; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, Brazil., Wurst W; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany; Technische Universität München-Weihenstephan, Chair of Developmental Genetics, c/o Helmholtz Zentrum München, 85764 Neuherberg, Germany., Ursini F; Department of Molecular Medicine, University of Padova, Padova, Italy., Arnér ESJ; Division of Biochemistry, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 77 Stockholm, Sweden., Fradejas-Villar N; Rheinische Friedrich-Wilhelms-University Bonn, Institute for Biochemistry and Molecular Biology, 53115 Bonn, Germany., Schweizer U; Rheinische Friedrich-Wilhelms-University Bonn, Institute for Biochemistry and Molecular Biology, 53115 Bonn, Germany., Zischka H; Institute of Toxicology and Environmental Hygiene, Technical University of Munich, 80802 Munich, Germany; Helmholtz Zentrum München, Institute of Molecular Toxicology and Pharmacology, 85764 Neuherberg, Germany., Friedmann Angeli JP; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany., Conrad M; Helmholtz Zentrum München, Institute of Developmental Genetics, 85764 Neuherberg, Germany. Electronic address: marcus.conrad@helmholtz-muenchen.de.

المصدر: Cell [Cell] 2018 Jan 25; Vol. 172 (3), pp. 409-422.e21. Date of Electronic Publication: 2017 Dec 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*, Glutathione Peroxidase/*metabolism , Seizures/*metabolism , Selenium/*metabolism, Animals ; Cell Survival ; Cells, Cultured ; Female ; Glutathione Peroxidase/genetics ; HEK293 Cells ; Humans ; Hydrogen Peroxide/toxicity ; Interneurons/metabolism ; Lipid Peroxidation ; Male ; Mice ; Mice, Inbred C57BL ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Seizures/etiology

المؤلفون: Cozza G; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Rossetto M; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Bosello-Travain V; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Maiorino M; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Roveri A; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Toppo S; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Zaccarin M; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Zennaro L; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy., Ursini F; Department of Molecular Medicine, University of Padova, Viale G. Colombo, 3, I-35121 Padova, Italy. Electronic address: fulvio.ursini@unipd.it.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2017 Nov; Vol. 112, pp. 1-11. Date of Electronic Publication: 2017 Jul 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Cardiolipins/*chemistry , Glutathione Peroxidase/*chemistry , Lipid Peroxides/*chemistry , Liposomes/*chemistry , Phosphatidylcholines/*chemistry, Amino Acid Sequence ; Animals ; Binding Sites ; Biocatalysis ; Cardiolipins/metabolism ; Gene Expression ; Glutathione Peroxidase/isolation & purification ; Glutathione Peroxidase/metabolism ; HEK293 Cells ; Humans ; Kinetics ; Lipid Peroxides/metabolism ; Liposomes/metabolism ; Male ; Molecular Docking Simulation ; Oxidation-Reduction ; Phosphatidylcholines/metabolism ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Rats ; Sequence Alignment ; Sequence Homology, Amino Acid ; Static Electricity ; Substrate Specificity ; Testis/chemistry ; Testis/enzymology

المؤلفون: Orian L; Department of Chemistry, University of Padova, Italy., Mauri P; Institute for Biomedical Technologies, National Research Council, Milano, Italy., Roveri A; Department of Molecular Medicine, University of Padova, Italy., Toppo S; Department of Molecular Medicine, University of Padova, Italy., Benazzi L; Institute for Biomedical Technologies, National Research Council, Milano, Italy., Bosello-Travain V; Department of Molecular Medicine, University of Padova, Italy., De Palma A; Institute for Biomedical Technologies, National Research Council, Milano, Italy., Maiorino M; Department of Molecular Medicine, University of Padova, Italy., Miotto G; Department of Molecular Medicine, University of Padova, Italy., Zaccarin M; Department of Molecular Medicine, University of Padova, Italy., Polimeno A; Department of Chemistry, University of Padova, Italy., Flohé L; Department of Molecular Medicine, University of Padova, Italy. Electronic address: l.flohe@t-online.de., Ursini F; Department of Molecular Medicine, University of Padova, Italy.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2015 Oct; Vol. 87, pp. 1-14. Date of Electronic Publication: 2015 Jul 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Oxidation-Reduction*, Glutathione/*chemistry , Glutathione Peroxidase/*chemistry , Selenocysteine/*chemistry, Animals ; Catalysis ; Glutathione/metabolism ; Glutathione Peroxidase/metabolism ; Hydrogen Peroxide/chemistry ; Kinetics ; Quantum Theory ; Rats ; Selenium/chemistry ; Selenocysteine/metabolism ; Sulfur/chemistry ; Tandem Mass Spectrometry

المؤلفون: Ingold I; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Aichler M; Research Unit Analytical Pathology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Yefremova E; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Roveri A; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy., Buday K; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Doll S; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Tasdemir A; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Hoffard N; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Wurst W; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany, Deutsches Zentrum für Neurodegenerative Erkrankungen e. V. (DZNE) Standort München, Schillerstrasse 44, 80336 Munich, Germany, Munich Cluster for Systems Neurology (SyNergy) Adolf-Butenandt-Institut Ludwig-Maximilians-Universität München, Schillerstrasse 44, 80336 Munich, Germany, and Technische Universität München-Weihenstephan, Lehrstuhl für Entwicklungsgenetik c/o Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Walch A; Research Unit Analytical Pathology, Helmholtz Zentrum München, Ingolstädter Landstrasse 1, 85764 Neuherberg, Germany., Ursini F; Department of Molecular Medicine, University of Padova, 35121 Padova, Italy., Friedmann Angeli JP; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany., Conrad M; From the Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Developmental Genetics, Ingolstädter Landstrassse 1, 85764 Neuherberg, Germany, marcus.conrad@helmholtz-muenchen.de.

المصدر: The Journal of biological chemistry [J Biol Chem] 2015 Jun 05; Vol. 290 (23), pp. 14668-78. Date of Electronic Publication: 2015 Apr 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Amino Acid Substitution* , Spermatogenesis*, Glutathione Peroxidase/*genetics , Glutathione Peroxidase/*metabolism , Infertility, Male/*genetics, Animals ; Catalytic Domain ; Cells, Cultured ; Embryo Loss/genetics ; Embryo Loss/metabolism ; Embryo Loss/pathology ; Female ; Heterozygote ; Homozygote ; Infertility, Male/metabolism ; Infertility, Male/pathology ; Male ; Mice ; Mice, Transgenic ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Selenocysteine/genetics ; Serine/genetics ; Spermatozoa/metabolism ; Spermatozoa/pathology ; Spermatozoa/ultrastructure

المؤلفون: Flohé L; Otto-von-Guericke-Universität and MOLISA GmbH, Magdeburg, Germany. l.flohe@t-online.de, Toppo S, Cozza G, Ursini F

المصدر: Antioxidants & redox signaling [Antioxid Redox Signal] 2011 Aug 01; Vol. 15 (3), pp. 763-80. Date of Electronic Publication: 2010 Nov 01.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

مواضيع طبية MeSH: Glutathione Peroxidase/*chemistry , Peroxiredoxins/*chemistry , Sulfhydryl Compounds/*chemistry, Catalysis ; Catalytic Domain ; Cysteine/chemistry ; Hydrogen Peroxide/chemistry ; Oxidation-Reduction ; Peroxynitrous Acid/chemistry ; Protein Conformation ; Selenocysteine/chemistry ; Signal Transduction

المؤلفون: Toppo S; Department of Biological Chemistry, Viale G. Colombo, 3, University of Padova, I-35121 Padova, Italy., Flohé L, Ursini F, Vanin S, Maiorino M

المصدر: Biochimica et biophysica acta [Biochim Biophys Acta] 2009 Nov; Vol. 1790 (11), pp. 1486-500. Date of Electronic Publication: 2009 Apr 17.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Pub. Co Country of Publication: Netherlands NLM ID: 0217513 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0006-3002 (Print) Linking ISSN: 00063002 NLM ISO Abbreviation: Biochim Biophys Acta Subsets: MEDLINE

مواضيع طبية MeSH: Models, Chemical*, Glutathione Peroxidase/*metabolism, Animals ; Catalysis ; Glutathione Peroxidase/chemistry ; Glutathione Peroxidase/genetics ; Glutathione Peroxidase/physiology ; Humans ; Models, Biological ; Models, Molecular ; Oxidation-Reduction ; Phylogeny ; Substrate Specificity

المؤلفون: Schneider M; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Förster H, Boersma A, Seiler A, Wehnes H, Sinowatz F, Neumüller C, Deutsch MJ, Walch A, Hrabé de Angelis M, Wurst W, Ursini F, Roveri A, Maleszewski M, Maiorino M, Conrad M

المصدر: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2009 Sep; Vol. 23 (9), pp. 3233-42. Date of Electronic Publication: 2009 May 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE

مواضيع طبية MeSH: Glutathione Peroxidase/*physiology , Infertility, Male/*etiology , Mitochondrial Proteins/*physiology, Animals ; Apoptosis ; Embryonic Development ; Glutathione Peroxidase/deficiency ; Male ; Mice ; Phospholipid Hydroperoxide Glutathione Peroxidase ; Selenium/physiology ; Spermatozoa/pathology

المؤلفون: Tosatto SC; Department of Biology and CRIBI Biotechnology Centre, Padova, Italy., Bosello V, Fogolari F, Mauri P, Roveri A, Toppo S, Flohé L, Ursini F, Maiorino M

المصدر: Antioxidants & redox signaling [Antioxid Redox Signal] 2008 Sep; Vol. 10 (9), pp. 1515-26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 100888899 Publication Model: Print Cited Medium: Internet ISSN: 1557-7716 (Electronic) Linking ISSN: 15230864 NLM ISO Abbreviation: Antioxid Redox Signal Subsets: MEDLINE

مواضيع طبية MeSH: Glutathione Peroxidase/*chemistry , Glutathione Peroxidase/*metabolism, Amino Acid Sequence ; Animals ; Binding Sites/genetics ; Catalytic Domain/genetics ; Drosophila melanogaster/enzymology ; Glutathione Peroxidase/genetics ; Humans ; Hydrogen Bonding ; Isoenzymes/chemistry ; Isoenzymes/genetics ; Isoenzymes/metabolism ; Kinetics ; Mass Spectrometry ; Models, Molecular ; Molecular Sequence Data ; Molecular Structure ; Mutation ; Protein Structure, Secondary ; Protein Structure, Tertiary ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Homology, Amino Acid ; Thioredoxin-Disulfide Reductase/chemistry ; Thioredoxin-Disulfide Reductase/genetics ; Thioredoxin-Disulfide Reductase/metabolism

المؤلفون: Maiorino M; Department of Biological Chemistry, University of Padova, I-35121 Padova, Italy. matilde.maiorino@unipd.it, Ursini F, Bosello V, Toppo S, Tosatto SC, Mauri P, Becker K, Roveri A, Bulato C, Benazzi L, De Palma A, Flohé L

المصدر: Journal of molecular biology [J Mol Biol] 2007 Jan 26; Vol. 365 (4), pp. 1033-46. Date of Electronic Publication: 2006 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Print ISSN: 0022-2836 (Print) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Glutathione Peroxidase/*chemistry , Thioredoxins/*chemistry, Amino Acid Sequence ; Animals ; Dimerization ; Disulfides/chemistry ; Drosophila melanogaster ; Kinetics ; Models, Chemical ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Peroxidases/chemistry ; Peroxiredoxins ; Sequence Homology, Amino Acid ; Substrate Specificity