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21
المؤلفون: Mark E. Bowen, Tsutomu Matsui, Jasmin Weisemann, Andreas Rummel, Rongsheng Jin, Kwok-Ho Lam, Kay Perry, Zhuojun Guo, Nadja Krez
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Lam, Kwok-Ho; Guo, Zhuojun; Krez, Nadja; Matsui, Tsutomu; Perry, Kay; Weisemann, Jasmin; et al.(2018). A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1.. Nature communications, 9(1), 5367. doi: 10.1038/s41467-018-07789-4. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/99m85024
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Endosome, medicine.medical_treatment, Science, Protein domain, Neurotoxins, General Physics and Astronomy, Endosomes, Crystallography, X-Ray, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Cytosol, Viral Envelope Proteins, Protein Domains, MD Multidisciplinary, medicine, Amino Acid Sequence, Botulinum Toxins, Type A, lcsh:Science, Peptide sequence, Molecular switch, Neurons, Liposome, Multidisciplinary, Protease, Chemistry, Vesicle, General Chemistry, Intracellular Membranes, Hydrogen-Ion Concentration, Recombinant Proteins, 030104 developmental biology, Liposomes, Biophysics, lcsh:Q, Sequence Alignment, Hydrophobic and Hydrophilic Interactions
وصف الملف: application/pdf
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المصدر: Parasites & Vectors, Vol 11, Iss 1, Pp 1-16 (2018)
Parasites & Vectorsمصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Parasite Encystment, Opisthokont, Gene duplication, Pseudogene, Protozoan Proteins, Endosomes, Saccharomyces cerevisiae, Flagellum, medicine.disease_cause, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, Stress, Physiological, Encystation, medicine, Functional divergence, Giardia lamblia, lcsh:RC109-216, Amino Acid Sequence, Trophozoites, NSF, Gene, Phylogeny, biology, integumentary system, α-SNAP, Research, Genetic Complementation Test, biology.organism_classification, Subcellular localization, Cell biology, Cell Compartmentation, Vesicular transport protein, Soluble N-Ethylmaleimide-Sensitive Factor Attachment Proteins, 030104 developmental biology, Infectious Diseases, SNARE, Oxidative stress, Parasitology
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المؤلفون: Jonathan Stuckey, Pengfei Wang, Jason Gorman, Mallika Sastry, Phinikoula S. Katsamba, Wei Shi, Alexandra Nazzari, Micah Rapp, Arne Schön, Tyler Stephens, David D. Ho, Jude Bimela, Yaroslav Tsybovsky, Shuishu Wang, Tongqing Zhou, Lawrence Shapiro, John R. Mascola, Jeffrey C. Boyington, Gwo-Yu Chuang, Adam S. Olia, I-Ting Teng, Richard A. Friesner, Baoshan Zhang, Jared M. Sampson, Gabriele Cerutti, Peter D. Kwong
المصدر: Cell Host & Microbe
bioRxivمصطلحات موضوعية: receptor-binding domain (RBD), Endosome, Cryo-electron microscopy, Protein domain, Trimer, Plasma protein binding, Endosomes, pH-dependent switch, Biology, Microbiology, Article, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Viral entry, Virology, Humans, Amino Acid Sequence, Binding site, Peptide sequence, Pandemics, 030304 developmental biology, 0303 health sciences, Binding Sites, SARS-CoV-2, type 1 fusion machine, Cryoelectron Microscopy, structural rearrangement, COVID-19, Hydrogen-Ion Concentration, Antibodies, Neutralizing, Spike Glycoprotein, Coronavirus, Biophysics, Receptors, Virus, Parasitology, Angiotensin-Converting Enzyme 2, endosomal entry, 030217 neurology & neurosurgery, hormones, hormone substitutes, and hormone antagonists, ACE2 receptor, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88be1a20b596474f1bf53112475fea25
http://europepmc.org/articles/PMC7670890 -
24
المؤلفون: Stephen C. Kales, A. Kurt Gamperl, Collen Ryan, Kazuhiro Fujiki, Brian Dixon, Aaron P. Frenette, Marije Booman
المصدر: Molecular immunology. 129
مصطلحات موضوعية: 0301 basic medicine, Cytoplasm, Glycosylation, Transcription, Genetic, Lineage (evolution), T-Lymphocytes, Immunology, Antigen presentation, Endosomes, Major histocompatibility complex, 03 medical and health sciences, 0302 clinical medicine, Cross-Priming, biology.animal, Gadus, Animals, Amino Acid Sequence, Antigens, Molecular Biology, Antigen Presentation, Genome, biology, Gadiformes, Histocompatibility Antigens Class I, Vertebrate, Haddock, biology.organism_classification, 030104 developmental biology, Gadus morhua, Evolutionary biology, biology.protein, Atlantic cod, beta 2-Microglobulin, Sequence Alignment, 030215 immunology, Signal Transduction
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25
المؤلفون: Jean-François Côté, Daniel Figeys, Stéphanie Duval, Deeptee Seebun, Janice Mayne, Islam E. Elkholi, Nabil G. Seidah, Rui Chen, Afnan Abu-Thuraia
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 11, Iss 8, Pp 1-15 (2020)مصطلحات موضوعية: Proteomics, Cancer Research, Endosome, Immunology, Triple Negative Breast Neoplasms, Endosomes, Biochemistry, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Amino Acid Sequence, Subtilisins, lcsh:QH573-671, Furin, 030304 developmental biology, 0303 health sciences, biology, lcsh:Cytology, Tumor Suppressor Proteins, HEK 293 cells, Cancer, Cell migration, Cell Biology, Proteases, Actin cytoskeleton, medicine.disease, Phenotype, Cell biology, Neoplasm Proteins, Protein Transport, HEK293 Cells, 030220 oncology & carcinogenesis, biology.protein, Disease Progression, Hepatocytes, Proprotein Convertases, Protein Processing, Post-Translational
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26
المؤلفون: Shuangshuang Ji, Hao Fei, Xiaolong Chen, Hanjie Liu, Ang Li
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: conformation, Conformational change, LAMP-1, lysosomal-associated membrane protein 1, Peptide, CMP-Neu5Ac, cytidine 5′-monophospho-N-acetylneuraminic acid, ANS-Na, sodium 8-Anilino-1-naphthalenesulfonate, Biochemistry, 3Fax-Neu5Ac, 3Fax-Peracetyl Neu5Ac, Cell membrane, Gly-lit, glycolithocholic acid, anion sensitivity, chemistry.chemical_classification, IgG, Immunoglobulin G, Chemistry, BafA1, bafilomycin A1, CPP, cell-penetrating peptides, CAPs, cationic amphipathic peptides, Peptide Conformation, medicine.anatomical_structure, Membrane, TFE, 2,2,2-trifluoroethanol, FITC, fluorescein isothiocyanate, Hydrophobic and Hydrophilic Interactions, Research Article, IC50, the half inhibitory concentration, Anions, LAMP-2, lysosomal-associated membrane protein 2, cationic amphipathic peptides, CLSM, confocal laser scanning microscope, Endosomes, NY, nystatin, PI, propidium iodide, PBS, phosphate buffer saline, EIPA, amiloride, LUVs, large unilamellar vesicles, SAP, saporin, Amphiphile, medicine, Membrane activity, Amino Acid Sequence, CPZ, chlorpromazine, Molecular Biology, IC20, the 20% inhibitory concentration, hydrophobicity, endosomolytic delivery, Cell Membrane, Cell Biology, Lysosomal-Associated Membrane Protein 1, PSA, polysialic acid, GRAVY, the grand average of hydropathy, Biophysics, LC50, the half leakage concentration, DOPC, dioleoyl phosphatidylcholine, Peptides, DOPG, dioleoyl phosphatidylglycerole
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e5bcc1c77a58618c41d844f8e23287
https://doi.org/10.1016/j.jbc.2021.101364 -
27
المؤلفون: Dobner, Jochen, Simons, Indra M., Willbold, Dieter, Rufinatscha, Kerstin, Hänsch, Sebastian, Schwarten, Melanie, Weiergräber, Oliver H., Abdollahzadeh, Iman, Gensch, Thomas, Bode, Johannes G., Hoffmann, Silke
المصدر: Cells
Volume 9
Issue 5
Cells, Vol 9, Iss 1296, p 1296 (2020)
Cells 9(5), 1296-(2020). doi:10.3390/cells9051296مصطلحات موضوعية: Astrophysics::High Energy Astrophysical Phenomena, EGFR, GABARAP, Endosomes, Models, Biological, Article, ddc:570, Cell Line, Tumor, Humans, genome editing, Amino Acid Sequence, Phosphorylation, Transport Vesicles, lcsh:QH301-705.5, Adaptor Proteins, Signal Transducing, Fluorescent Dyes, degradation, Epidermal Growth Factor, Sequence Homology, Amino Acid, Autophagy-Related Protein 8 Family, receptor trafficking, Endocytosis, ErbB Receptors, HEK293 Cells, Gene Expression Regulation, lcsh:Biology (General), Proteolysis, Apoptosis Regulatory Proteins, Lysosomes, Atg8, Microtubule-Associated Proteins, Proteasome Inhibitors, Signal Transduction
وصف الملف: application/pdf
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المؤلفون: Fang Sun, Yuewen Han, Jean-Marc Sabatier, Yingliang Wu, Minjun Gao, Zhijian Cao, Lixia Miao, Zhiqiang Xia, Luyao Wang
المساهمون: Wuhan University [China], Institut de neurophysiopathologie (INP), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Viruses, Vol 12, Iss 3, p 295 (2020)
Viruses
Viruses, MDPI, 2020, 12 (3), pp.295. ⟨10.3390/v12030295⟩
Volume 12
Issue 3
Viruses, 2020, 12 (3), pp.295. ⟨10.3390/v12030295⟩مصطلحات موضوعية: 0301 basic medicine, topology, Endosome, [SDV]Life Sciences [q-bio], 030106 microbiology, lcsh:QR1-502, mechanism, Endosomes, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Dengue virus, Virus Replication, Topology, medicine.disease_cause, Antiviral Agents, Article, lcsh:Microbiology, Zika virus, 03 medical and health sciences, Virology, Chlorocebus aethiops, Organelle, medicine, Animals, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Amino Acid Sequence, Vero Cells, antiviral functional residues, biology, Zika Virus Infection, Chemistry, Cell Membrane, ifitm1, Membrane Proteins, Zika Virus, biology.organism_classification, Antigens, Differentiation, Transmembrane protein, 3. Good health, Cytosol, HEK293 Cells, 030104 developmental biology, Infectious Diseases, Cytoplasm, Interferons, Sequence Alignment, Intracellular
وصف الملف: application/pdf
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المؤلفون: Boning, Cao, Zhongqiang, Xia, Changying, Liu, Wei, Fan, Shuai, Zhang, Qiao, Liu, Zhonghuai, Xiang, Aichun, Zhao
المصدر: International Journal of Molecular Sciences
مصطلحات موضوعية: Models, Molecular, Na+, K+/H+ antiporters, homology modeling, Arabidopsis, Reproducibility of Results, Endosomes, Saccharomyces cerevisiae, Salt Tolerance, Plants, Genetically Modified, Antiporters, Article, Evolution, Molecular, ion transport, Structure-Activity Relationship, mulberry, Phenotype, Mutation, salt-stress, Amino Acid Sequence, Morus, Hydrophobic and Hydrophilic Interactions, Conserved Sequence, Plant Proteins
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المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)مصطلحات موضوعية: 0301 basic medicine, Aging, T-Lymphocytes, Antigen presentation, Receptors, Antigen, T-Cell, lcsh:Medicine, Mice, Transgenic, Human leukocyte antigen, Endosomes, Biology, Cross Reactions, Major histocompatibility complex, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, Influenza A Virus, H1N1 Subtype, Orthomyxoviridae Infections, Immunity, Animals, Amino Acid Sequence, lcsh:Science, Late endosome, Multidisciplinary, Innate immune system, Polymorphism, Genetic, Influenza A Virus, H3N2 Subtype, lcsh:R, Vaccination, Histocompatibility Antigens Class II, virus diseases, Acquired immune system, Survival Analysis, Mice, Inbred C57BL, 030104 developmental biology, Influenza Vaccines, 030220 oncology & carcinogenesis, Immunology, biology.protein, lcsh:Q, Influenza virus, Lysosomes
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