المؤلفون: Anne-Marie Lambeir, An Bracke, Ingrid De Meester, Emilie De Hert, Pieter Van der Veken

المصدر: Biochemical pharmacology

مصطلحات موضوعية: Cell, Angiotensin-Converting Enzyme Inhibitors, Carboxypeptidases, Pharmacology, Cleavage (embryo), Biochemistry, Umbilical vein, Prolyl endopeptidase, Renin–angiotensin system, medicine, Human Umbilical Vein Endothelial Cells, Humans, Biology, Aorta, Cells, Cultured, chemistry.chemical_classification, Pharmacology. Therapy, Angiotensin II, Angiotensin III, Chemistry, medicine.anatomical_structure, Enzyme, chemistry, Angiotensin-converting enzyme 2, Human medicine, Peptides, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6fd8d2e540d04e26aab529ff06c8e85
https://pubmed.ncbi.nlm.nih.gov/34418354

المؤلفون: Aurélie Breuer, Mégane Van Gysel, Benjamin Le Calvé, Thomas Dal Maso, Johan Wouters, Carine Michiels, Sébastien Marx

المصدر: Biochemical Pharmacology. 162:224-236

مصطلحات موضوعية: Thiosemicarbazones, 0301 basic medicine, Programmed cell death, Paclitaxel, Taxol, Chemosensitizer, Antineoplastic Agents, Apoptosis, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Hypoxia, Etoposide, Cancer, Pharmacology, Oncogene, Chemistry, Drug Synergism, Hep G2 Cells, Hypoxia (medical), DNA Fingerprinting, Cell Hypoxia, 030104 developmental biology, Mechanism of action, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, medicine.symptom, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd9d8d6e6cac71a6bea5ead6a192247
https://doi.org/10.1016/j.bcp.2019.01.004

المؤلفون: Johannes A. Kroes, Sander Wilhelm Zielhuis, E.N. Van Roon, A. ten Brinke

المصدر: Biochemical pharmacology. 179

مصطلحات موضوعية: 0301 basic medicine, Male, SEVERE ALLERGIC-ASTHMA, Omalizumab, INHALED CORTICOSTEROIDS, Biochemistry, Biomarkers, Pharmacological, chemistry.chemical_compound, DOUBLE-BLIND, 0302 clinical medicine, Reslizumab, QUALITY-OF-LIFE, Anti-Asthmatic Agents, Precision Medicine, ELECTRONIC NOSE, Antibodies, Monoclonal, Benralizumab, Dupilumab, Treatment Outcome, Breath Tests, 030220 oncology & carcinogenesis, Female, Inflammation Mediators, Drug Monitoring, medicine.drug, EXHALED NITRIC-OXIDE, medicine.medical_specialty, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, medicine, Humans, IGE, Intensive care medicine, Asthma, Pharmacology, Biological Products, business.industry, MEPOLIZUMAB, SERUM INFLIXIMAB, Immunoglobulin E, medicine.disease, RHEUMATOID-ARTHRITIS, Clinical trial, 030104 developmental biology, chemistry, Exhaled nitric oxide, Interleukin-5, business, Mepolizumab, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f8c9f196e25497995d0194b1d167f9
https://pubmed.ncbi.nlm.nih.gov/32305434

المؤلفون: Gustav van Niekerk, Ben Loos, Anna-Mart Engelbrecht, Jade Peres, Tanja Davis, Sharon Prince

المصدر: Biochemical Pharmacology. 148:174-183

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Cell cycle checkpoint, Breast Neoplasms, Biochemistry, Caspase 7, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, Doxorubicin, Cellular localization, Pharmacology, Antibiotics, Antineoplastic, Chemistry, Membrane Proteins, Cancer, medicine.disease, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Female, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39e4c4c8dff7dae6a01d6d9425e269c7
https://doi.org/10.1016/j.bcp.2018.01.012

المؤلفون: Sharon Prince, Serah Kimani, Ikponmwosa Irene, Selwyn F. Mapolie, Adrienne L. Edkins, Suparna Chakraborty, André du Toit, K.N. ArulJothi, Letícia V. Costa-Lotufo, Angelique Blanckenberg, Annick van Niekerk, Ben Loos, Jo de la Mare

المصدر: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Paclitaxel, Breast Neoplasms, Chick Embryo, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Breast cancer, medicine, Animals, Humans, Pharmacology, Cisplatin, Chemistry, CÉLULAS CULTIVADAS DE TUMOR, Cancer, Cell cycle, medicine.disease, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell, MCF-7 Cells, Neoplastic Stem Cells, Cancer research, Female, Stem cell, Palladium, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab3d9be99b4a88e1da735029146295e
https://doi.org/10.1016/j.bcp.2021.114598

المؤلفون: Henk L. Dekker, Elisa Giovannetti, Marcello Tiseo, Patrick Pauwels, Filip Lardon, Christian Rolfo, Kaylee Keller, Rob Ruijtenbeek, Alessandro Leonetti, Niccola Funel, Godefridus J. Peters, Nele Van Der Steen

المساهمون: Medical oncology laboratory, AGEM - Re-generation and cancer of the digestive system, CCA - Cancer biology and immunology

المصدر: Biochemical pharmacology
van der Steen, N, Leonetti, A, Keller, K, Dekker, H, Funel, N, Lardon, F, Ruijtenbeek, R, Tiseo, M, Rolfo, C, Pauwels, P, Peters, G J & Giovannetti, E 2019, ' Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line ', Biochemical Pharmacology, vol. 166, pp. 128-138 . https://doi.org/10.1016/j.bcp.2019.05.014
Biochemical Pharmacology, 166, 128-138. Elsevier Inc.

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, Lung Neoplasms, Antineoplastic Agents, Biochemistry, 03 medical and health sciences, Erlotinib Hydrochloride, 0302 clinical medicine, Crizotinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Epidermal growth factor receptor, Phosphorylation, Lung cancer, Protein kinase B, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Aged, Pharmacology, biology, Chemistry, Pharmacology. Therapy, Drug Synergism, Cell cycle, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, ErbB Receptors, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Erlotinib, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::198c1da7976161631dcc7ca088486798
https://hdl.handle.net/10067/1611930151162165141

المؤلفون: Adriaan P. IJzerman, Xue Yang, Laura H. Heitman, Daan van der Es, Majlen A. Dilweg, Dion Osemwengie, Lindsey Burggraaff

المصدر: Biochemical Pharmacology
Biochemical Pharmacology, 180, 114144

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.drug_class, adenosine A(1) receptor, Biochemistry, Partial agonist, 03 medical and health sciences, Adenosine A1 receptor, 0302 clinical medicine, G protein-coupled receptors, Radioligand binding, medicine, Inverse agonist, Receptor, G protein-coupled receptor, Pharmacology, Chemistry, Covalent ligand, Adenosine, Label-free assay, 030104 developmental biology, Docking (molecular), 030220 oncology & carcinogenesis, Biophysics, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356f1c997d125d8ef7860671f3d6cef5
https://doi.org/10.1016/j.bcp.2020.114144

المؤلفون: Palle Christophersen, Jacobsen Thomas Amos, Dan Peters, Altair Brito dos Santos, Philip K. Ahring, Jessica Klein, Karin Sandager-Nielsen, Marloes van Hout, Kristi A. Kohlmeier, Anders A. Jensen, Siganya Thaneshwaran, Tino Dyhring, Dipak Vasantrao Amrutkar

المصدر: Biochemical Pharmacology. 174:113786

مصطلحات موضوعية: Male, 0301 basic medicine, Agonist, Patch-Clamp Techniques, medicine.drug_class, Dopamine, Drug Evaluation, Preclinical, Action Potentials, Substantia nigra, Receptors, Nicotinic, Biochemistry, Rats, Sprague-Dawley, Mice, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Mesencephalon, medicine, Animals, Humans, Neurotoxin, Calcium Signaling, Nicotinic Agonists, Rats, Wistar, Pharmacology, Dose-Response Relationship, Drug, Chemistry, Pars compacta, Dopaminergic, Rats, HEK293 Cells, Neuroprotective Agents, 030104 developmental biology, Nicotinic agonist, medicine.anatomical_structure, nervous system, Dopaminergic pathways, 030220 oncology & carcinogenesis, Oocytes, Neuroscience, Protein Binding, Synaptosomes, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::869843e3bb718d143298dc648d94624c
https://doi.org/10.1016/j.bcp.2019.113786

المؤلفون: Anders A. Jensen, Altair Brito dos Santos, Palle Christophersen, Marloes van Hout, Philip K. Ahring, Jessica Klein, Siganya Thaneshwaran, Kristi A. Kohlmeier, David T. Brown, Tino Dyhring

المصدر: Biochemical Pharmacology. 174:113788

مصطلحات موضوعية: 0301 basic medicine, Nicotine, Patch-Clamp Techniques, Allosteric modulator, Dopamine, Action Potentials, Substantia nigra, Receptors, Nicotinic, Biochemistry, Rats, Sprague-Dawley, Mice, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, medicine, Animals, Humans, Calcium Signaling, Rats, Wistar, Receptor, Acetylcholine receptor, Pharmacology, Chemistry, Pars compacta, Dopaminergic Neurons, Dopaminergic, Brain, HEK293 Cells, Neuroprotective Agents, 030104 developmental biology, Nicotinic agonist, nervous system, 030220 oncology & carcinogenesis, Oocytes, Neuroscience, Synaptosomes, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ad3a4f1057989d191fba4c58996368
https://doi.org/10.1016/j.bcp.2019.113788

المؤلفون: Matthias Grill, Melanie Patt, Julien Boccard, Alex Odermatt, Serge Rudaz, Katharina Beck, Mohamed Salah, Chris J. van Koppen, Víctor González-Ruiz, Rolf W. Hartmann, Tobias Di Marco, Marie-Christin Jäger

المصدر: Biochemical Pharmacology, Vol. 172 (2020) P. 113781

مصطلحات موضوعية: 0301 basic medicine, Steroid biosynthesis, medicine.medical_specialty, Cell Survival, Adrenal Gland Neoplasms, Dehydroepiandrosterone, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Anabolic Agents, 0302 clinical medicine, Cytochrome P-450 Enzyme System, Cell Line, Tumor, Internal medicine, Adrenal Glands, Humans, Medicine, Mestanolone, H295R, Adrenal gland, Pharmacology, ddc:615, business.industry, Mesterolone, Clostebol, Cardiovascular disease, Androgen receptor, 030104 developmental biology, Endocrinology, Gene Expression Regulation, chemistry, 030220 oncology & carcinogenesis, Hypertension, Oxymetholone, Androgens, Methenolone, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669320a52bd3683d731c8bb698ca9b73
https://doi.org/10.1016/j.bcp.2019.113781