المؤلفون: Jin L; Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, Tokyo, Japan., Tabe Y, Lu H, Borthakur G, Miida T, Kantarjian H, Andreeff M, Konopleva M

المصدر: Cancer letters [Cancer Lett] 2013 Feb 01; Vol. 329 (1), pp. 45-58. Date of Electronic Publication: 2012 Oct 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Phosphoinositide-3 Kinase Inhibitors*, Antineoplastic Agents/*pharmacology , Bone Marrow/*drug effects , Indazoles/*pharmacology , Leukemia, Myeloid, Acute/*pathology , Niacinamide/*analogs & derivatives , Phenylurea Compounds/*pharmacology , Sulfonamides/*pharmacology , fms-Like Tyrosine Kinase 3/*antagonists & inhibitors, Apoptosis/drug effects ; Bone Marrow/metabolism ; Cell Hypoxia/drug effects ; Cellular Microenvironment/drug effects ; Coculture Techniques ; Enzyme Inhibitors/pharmacology ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Mutation ; Myeloid Cell Leukemia Sequence 1 Protein ; Niacinamide/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-pim-1/genetics ; Proto-Oncogene Proteins c-pim-1/metabolism ; Sorafenib ; Stromal Cells/drug effects ; Stromal Cells/metabolism ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism

المؤلفون: Blanco-Aparicio C; Spanish National Cancer Research Centre, Madrid, Spain., Collazo AM, Oyarzabal J, Leal JF, Albarán MI, Lima FR, Pequeño B, Ajenjo N, Becerra M, Alfonso P, Reymundo MI, Palacios I, Mateos G, Quiñones H, Corrionero A, Carnero A, Pevarello P, Lopez AR, Fominaya J, Pastor J, Bischoff JR

المصدر: Cancer letters [Cancer Lett] 2011 Jan 28; Vol. 300 (2), pp. 145-53. Date of Electronic Publication: 2010 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/metabolism , Phosphoinositide-3 Kinase Inhibitors*, Antineoplastic Agents/*pharmacology , Cell Proliferation/*drug effects , Proto-Oncogene Proteins c-pim-1/*antagonists & inhibitors , Pyridazines/*pharmacology, Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Synergism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Humans ; Immunoblotting ; Indazoles/pharmacology ; Pyridazines/chemistry ; Sulfonamides/pharmacology