المؤلفون: Broutian TR; Biomedical Sciences Graduate Program, Ohio State University, Columbus, OH, 43210, United States., Jiang B; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States., Li J; Division of Medical Oncology, Department of Internal Medicine, Ohio State University, Columbus, OH, 43210, United States., Akagi K; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States., Gui S; Division of Medical Oncology, Department of Internal Medicine, Ohio State University, Columbus, OH, 43210, United States., Zhou Z; Division of Medical Oncology, Department of Internal Medicine, Ohio State University, Columbus, OH, 43210, United States., Xiao W; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States., Symer DE; Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States. Electronic address: desymer@mdanderson.org., Gillison ML; Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, 77030, United States. Electronic address: mgillison@mdanderson.org.

المصدر: Cancer letters [Cancer Lett] 2020 Apr 28; Vol. 476, pp. 23-33. Date of Electronic Publication: 2020 Jan 17.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Head and Neck Neoplasms/*genetics , Human papillomavirus 16/*genetics , Papillomavirus Infections/*complications , Proto-Oncogene Proteins c-pim-1/*genetics , Squamous Cell Carcinoma of Head and Neck/*genetics , Virus Integration/*genetics, Animals ; Apoptosis ; Cell Proliferation ; Female ; Head and Neck Neoplasms/pathology ; Head and Neck Neoplasms/virology ; Humans ; Mice ; Mice, Nude ; Papillomavirus Infections/genetics ; Papillomavirus Infections/virology ; Prognosis ; Proto-Oncogene Proteins c-pim-1/antagonists & inhibitors ; Squamous Cell Carcinoma of Head and Neck/pathology ; Squamous Cell Carcinoma of Head and Neck/virology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

المؤلفون: Cao L; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, PR China., Wang F; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China., Li S; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China., Wang X; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China., Huang D; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China., Jiang R; Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, PR China; Key Laboratory of Cancer Prevention and Therapy, Tianjin, PR China; Department of Thoracic Oncology, Tianjin Lung Cancer Center, Tianjin Cancer Institute & Hospital, Tianjin Medical University, Tianjin, 300060, PR China. Electronic address: jiangricheng@tjmuch.com.

المصدر: Cancer letters [Cancer Lett] 2019 Mar 01; Vol. 444, pp. 116-126. Date of Electronic Publication: 2018 Dec 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma of Lung/*secondary , Carcinoma, Non-Small-Cell Lung/*pathology , Lung Neoplasms/*pathology , Neoplasm Recurrence, Local/*pathology , Proto-Oncogene Proteins c-met/*metabolism , Proto-Oncogene Proteins c-pim-1/*metabolism, Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/metabolism ; Animals ; Apoptosis ; Carcinoma, Non-Small-Cell Lung/genetics ; Carcinoma, Non-Small-Cell Lung/metabolism ; Cell Proliferation ; Female ; Follow-Up Studies ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Lymphatic Metastasis ; Male ; Mice ; Mice, Nude ; Middle Aged ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/metabolism ; Prognosis ; Proto-Oncogene Mas ; Proto-Oncogene Proteins c-met/genetics ; Proto-Oncogene Proteins c-pim-1/genetics ; Retrospective Studies ; Signal Transduction ; Survival Rate ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

المؤلفون: Zheng J; Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC, USA; Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, China., Sha Y; Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC, USA., Roof L; Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, USA., Foreman O; Genentech Research Oncology, Genentech Inc., San Francisco, CA, USA., Lazarchick J; Department of Pathology, Medical University of South Carolina, Charleston, SC, USA., Venkta JK; Division of Hematology and Oncology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA., Kozlowski C; Genentech Safety Assessment Pathology, Genentech Inc, San Francisco, CA, USA., Gasparetto C; Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC, USA., Chao N; Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC, USA., Ebens A; Genentech Research Oncology, Genentech Inc., San Francisco, CA, USA., Hu J; Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, China. Electronic address: drjiandahu@163.com., Kang Y; Division of Hematologic Malignancies and Cellular Therapy, Department of Medicine, Duke University Medical Center, Durham, NC, USA. Electronic address: yubin.kang@duke.edu.

المصدر: Cancer letters [Cancer Lett] 2019 Jan; Vol. 440-441, pp. 1-10. Date of Electronic Publication: 2018 Oct 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Ikaros Transcription Factor/*metabolism , Multiple Myeloma/*drug therapy , Multiple Myeloma/*metabolism , Peptide Hydrolases/*metabolism , Protein Kinase Inhibitors/*pharmacology , Proto-Oncogene Proteins c-pim-1/*antagonists & inhibitors, Adaptor Proteins, Signal Transducing ; Animals ; Down-Regulation/drug effects ; Humans ; Imidazoles/pharmacology ; Lenalidomide/pharmacology ; Mice ; Mice, Inbred C57BL ; Multiple Myeloma/enzymology ; Peptide Hydrolases/biosynthesis ; Proteasome Endopeptidase Complex/metabolism ; Proto-Oncogene Proteins c-pim-1/metabolism ; Pyridazines/pharmacology ; Signal Transduction/drug effects ; Ubiquitin-Protein Ligases ; Xenograft Model Antitumor Assays

المؤلفون: Hsu JL; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan., Leong PK; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan., Ho YF; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan., Hsu LC; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan., Lu PH; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan., Chen CS; Division of Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA., Guh JH; School of Pharmacy, National Taiwan University, No. 1, Sect. 1, Jen-Ai Road, Taipei 100, Taiwan. Electronic address: jhguh@ntu.edu.tw.

المصدر: Cancer letters [Cancer Lett] 2012 Jun 28; Vol. 319 (2), pp. 214-222. Date of Electronic Publication: 2012 Jan 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: DNA End-Joining Repair/*drug effects , Histones/*genetics , Paclitaxel/*pharmacology , Prostatic Neoplasms/*genetics , Proto-Oncogene Proteins c-pim-1/*genetics, Apoptosis/genetics ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Helicases/metabolism ; DNA-Binding Proteins/metabolism ; Drug Resistance, Neoplasm/drug effects ; Gene Knockdown Techniques ; Humans ; Ku Autoantigen ; Male ; Microtubules/genetics ; Prostatic Neoplasms/drug therapy ; Proto-Oncogene Proteins c-pim-1/antagonists & inhibitors

المؤلفون: Jin L; Department of Clinical Laboratory Medicine, Juntendo University School of Medicine, Tokyo, Japan., Tabe Y, Lu H, Borthakur G, Miida T, Kantarjian H, Andreeff M, Konopleva M

المصدر: Cancer letters [Cancer Lett] 2013 Feb 01; Vol. 329 (1), pp. 45-58. Date of Electronic Publication: 2012 Oct 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Phosphoinositide-3 Kinase Inhibitors*, Antineoplastic Agents/*pharmacology , Bone Marrow/*drug effects , Indazoles/*pharmacology , Leukemia, Myeloid, Acute/*pathology , Niacinamide/*analogs & derivatives , Phenylurea Compounds/*pharmacology , Sulfonamides/*pharmacology , fms-Like Tyrosine Kinase 3/*antagonists & inhibitors, Apoptosis/drug effects ; Bone Marrow/metabolism ; Cell Hypoxia/drug effects ; Cellular Microenvironment/drug effects ; Coculture Techniques ; Enzyme Inhibitors/pharmacology ; Humans ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Mutation ; Myeloid Cell Leukemia Sequence 1 Protein ; Niacinamide/pharmacology ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-pim-1/genetics ; Proto-Oncogene Proteins c-pim-1/metabolism ; Sorafenib ; Stromal Cells/drug effects ; Stromal Cells/metabolism ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism

المؤلفون: Zang C; Charité-Universitätsmedizin Berlin, Department of Oncology and Hematology, Berlin, Germany., Eucker J, Liu H, Müller A, Possinger K, Scholz CW

المصدر: Cancer letters [Cancer Lett] 2013 Oct 10; Vol. 339 (2), pp. 288-97. Date of Electronic Publication: 2012 Nov 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*/drug effects , Phosphoinositide-3 Kinase Inhibitors*, Lymphoma, Large B-Cell, Diffuse/*genetics , Lymphoma, Large B-Cell, Diffuse/*metabolism , Proto-Oncogene Proteins c-bcl-2/*genetics , TOR Serine-Threonine Kinases/*antagonists & inhibitors, Adaptor Proteins, Signal Transducing/metabolism ; Cell Cycle Checkpoints/drug effects ; Cell Cycle Checkpoints/genetics ; Cell Cycle Proteins ; Cell Death/genetics ; Cell Line, Tumor ; Everolimus ; Humans ; Imidazoles/pharmacology ; Myeloid Cell Leukemia Sequence 1 Protein ; NF-kappa B/metabolism ; Phosphatidylinositol 3-Kinase/metabolism ; Phosphoproteins/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-akt/metabolism ; Proto-Oncogene Proteins c-pim-1/metabolism ; Quinolines/pharmacology ; RNA Interference ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Signal Transduction ; Sirolimus/analogs & derivatives ; Sirolimus/pharmacology ; TOR Serine-Threonine Kinases/metabolism

المؤلفون: Blanco-Aparicio C; Spanish National Cancer Research Centre, Madrid, Spain., Collazo AM, Oyarzabal J, Leal JF, Albarán MI, Lima FR, Pequeño B, Ajenjo N, Becerra M, Alfonso P, Reymundo MI, Palacios I, Mateos G, Quiñones H, Corrionero A, Carnero A, Pevarello P, Lopez AR, Fominaya J, Pastor J, Bischoff JR

المصدر: Cancer letters [Cancer Lett] 2011 Jan 28; Vol. 300 (2), pp. 145-53. Date of Electronic Publication: 2010 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/metabolism , Phosphoinositide-3 Kinase Inhibitors*, Antineoplastic Agents/*pharmacology , Cell Proliferation/*drug effects , Proto-Oncogene Proteins c-pim-1/*antagonists & inhibitors , Pyridazines/*pharmacology, Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Synergism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Humans ; Immunoblotting ; Indazoles/pharmacology ; Pyridazines/chemistry ; Sulfonamides/pharmacology

المؤلفون: Zhengqiu Zhou, Keiko Akagi, Shanying Gui, Weihong Xiao, Jingfeng Li, Tatevik Broutian, Bo Jiang, David E. Symer, Maura L. Gillison

المصدر: Cancer Lett

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Cell cycle checkpoint, Virus Integration, PIM1, Mice, Nude, Apoptosis, medicine.disease_cause, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Proto-Oncogene Proteins c-pim-1, medicine, Tumor Cells, Cultured, Animals, Humans, Epidermal growth factor receptor, Cell Proliferation, Gene knockdown, Human papillomavirus 16, biology, Kinase, Squamous Cell Carcinoma of Head and Neck, Papillomavirus Infections, Cancer, medicine.disease, Prognosis, Head and neck squamous-cell carcinoma, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, Head and Neck Neoplasms, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Female, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd791bbd284dbabb66af99f78ae57624
https://pubmed.ncbi.nlm.nih.gov/31958486

المؤلفون: Richeng Jiang, Shouying Li, Lianjing Cao, Dingzhi Huang, Xinyue Wang, Fan Wang

المصدر: Cancer letters. 444

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, C-Met, Lung Neoplasms, PIM1, Mice, Nude, Adenocarcinoma of Lung, Apoptosis, Biology, Proto-Oncogene Mas, Metastasis, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Proto-Oncogene Proteins c-pim-1, Carcinoma, Non-Small-Cell Lung, medicine, Tumor Cells, Cultured, Animals, Humans, EIF4B, Cell Proliferation, Retrospective Studies, Cell growth, Kinase, Middle Aged, Proto-Oncogene Proteins c-met, medicine.disease, Prognosis, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Survival Rate, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Lymphatic Metastasis, Cancer research, Adenocarcinoma, Female, Signal transduction, Neoplasm Recurrence, Local, Follow-Up Studies, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890b5a1be40eb9e4338571f72245d410
https://pubmed.ncbi.nlm.nih.gov/30583073

المؤلفون: Anja Müller, Christian Scholz, Hongyu Liu, Jan Eucker, Kurt Possinger, Chuanbing Zang

المصدر: Cancer letters. 339(2)

مصطلحات موضوعية: Cancer Research, Programmed cell death, Cell Cycle Proteins, Biology, mTORC2, Proto-Oncogene Proteins c-pim-1, immune system diseases, hemic and lymphatic diseases, Cell Line, Tumor, medicine, Humans, Everolimus, Phosphorylation, Protein kinase B, PI3K/AKT/mTOR pathway, B cell, Adaptor Proteins, Signal Transducing, Phosphoinositide-3 Kinase Inhibitors, Sirolimus, Cell Death, TOR Serine-Threonine Kinases, EIF4E, RPTOR, Imidazoles, NF-kappa B, Ribosomal Protein S6 Kinases, 70-kDa, Cell Cycle Checkpoints, Phosphoproteins, Cell biology, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Oncology, Proto-Oncogene Proteins c-bcl-2, Quinolines, Myeloid Cell Leukemia Sequence 1 Protein, RNA Interference, Lymphoma, Large B-Cell, Diffuse, Translation initiation complex, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b13d4ca69d2f3bb14b0e2814161bdd7
https://pubmed.ncbi.nlm.nih.gov/23200668