عنوان ترانسليتريتد: Dose de tolérance à l'irradiation des tissus sain: les testicules.

المؤلفون: Champetier C; Service de Radiothérapie, Hôpital de la Timone, 264 rue Saint-Pierre, 13005 Marseille, France. c.champetier@live.fr, Gross E, Pointreau Y, Zaccariotto A, Dubergé T, Guerder C, Ortholan C, Chauvet B

المصدر: Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique [Cancer Radiother] 2010 Jul; Vol. 14 (4-5), pp. 376-8. Date of Electronic Publication: 2010 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: France NLM ID: 9711272 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1769-6658 (Electronic) Linking ISSN: 12783218 NLM ISO Abbreviation: Cancer Radiother Subsets: MEDLINE

مواضيع طبية MeSH: Radiation Tolerance*, Radiotherapy/*adverse effects , Testis/*radiation effects, Adult ; Child ; Humans ; Hypogonadism/diagnostic imaging ; Infertility, Male/diagnostic imaging ; Infertility, Male/prevention & control ; Male ; Organ Preservation/methods ; Puberty/radiation effects ; Radionuclide Imaging ; Radiotherapy/methods ; Radiotherapy Dosage/standards ; Risk Assessment ; Testis/anatomy & histology ; Testis/physiology ; Truth Disclosure

مستخلص: Although there is very little evidence for direct irradiation of the testes, they may receive significant doses, especially in the treatment of pelvic tumors in adults and in pediatrics. The exocrine function of the testis seems to be more sensitive to radiotherapy. There is a risk of sterility, even after low doses of radiation. In the adult or the child who has reached puberty, we should propose a self-preservation of semen prior to radiotherapy. In pre-pubescent children, the problem is more delicate. In all cases, it is necessary to limit the dose to the testicles without affecting the coverage of tumour volume. Patients and/or their caregivers should be systematically informed of the risk of infertility related to irradiation.
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