المؤلفون: Martinez RS; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Salji MJ; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Rushworth L; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Ntala C; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Rodriguez Blanco G; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Hedley A; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Clark W; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Peixoto P; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France.; EPIGENExp, (EPIgenetics and GENe EXPression Technical Platform), Besançon, France., Hervouet E; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France.; EPIGENExp, (EPIgenetics and GENe EXPression Technical Platform), Besançon, France., Renaude E; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, Besançon, France.; EPIGENExp, (EPIgenetics and GENe EXPression Technical Platform), Besançon, France., Kung SHY; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Vancouver Prostate Centre, Vancouver, British Columbia, Canada., Galbraith LCA; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Nixon C; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Lilla S; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., MacKay GM; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Fazli L; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Vancouver Prostate Centre, Vancouver, British Columbia, Canada., Gaughan L; Northern Institute for Cancer Research, The Medical School, Newcastle University, Newcastle upon Tyne, United Kingdom., Sumpton D; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom., Gleave ME; Department of Urologic Sciences, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.; Vancouver Prostate Centre, Vancouver, British Columbia, Canada., Zanivan S; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom., Blomme A; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom. h.leung@beatson.gla.ac.uk a.blomme@uliege.be., Leung HY; CRUK Beatson Institute, Garscube Estate, Glasgow, United Kingdom. h.leung@beatson.gla.ac.uk a.blomme@uliege.be.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, United Kingdom.

المصدر: Cancer research [Cancer Res] 2021 Jul 01; Vol. 81 (13), pp. 3664-3678. Date of Electronic Publication: 2021 May 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Biomarkers, Tumor/*metabolism , Cell Cycle Proteins/*metabolism , Large Neutral Amino Acid-Transporter 1/*metabolism , Prostatic Neoplasms, Castration-Resistant/*pathology , TOR Serine-Threonine Kinases/*metabolism, Activating Transcription Factor 4/genetics ; Activating Transcription Factor 4/metabolism ; Animals ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Cycle Proteins/genetics ; Cell Proliferation ; Humans ; Large Neutral Amino Acid-Transporter 1/genetics ; Male ; Mechanistic Target of Rapamycin Complex 1/genetics ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Metabolome ; Mice ; Mice, Nude ; Prognosis ; Prostatic Neoplasms, Castration-Resistant/genetics ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Proteome ; Survival Rate ; TOR Serine-Threonine Kinases/genetics ; Transcriptome ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays