المؤلفون: Goldberg L; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Negi V; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Chung YJ; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Onozawa M; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Zhu YJ; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Walker RL; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Pierce R; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Patel DP; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Krausz KW; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Gonzalez FJ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Goodell MA; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas., Rodriguez BAT; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.; Valo Health, Boston, Massachusetts., Meltzer PS; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland., Aplan PD; Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland. aplanp@mail.nih.gov.

المصدر: Cancer research [Cancer Res] 2021 Oct 01; Vol. 81 (19), pp. 5033-5046. Date of Electronic Publication: 2021 Jul 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Homeodomain Proteins/*metabolism , Isocitrate Dehydrogenase/*genetics , Isocitrate Dehydrogenase/*metabolism , Nuclear Pore Complex Proteins/*metabolism , Oncogene Proteins, Fusion/*metabolism , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*etiology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*metabolism , Thymocytes/*metabolism, Animals ; Biomarkers, Tumor ; Cell Differentiation/genetics ; Cell Line, Tumor ; Computational Biology/methods ; DNA Methylation ; Disease Models, Animal ; Disease Susceptibility ; Gene Expression Profiling ; Heterografts ; Humans ; Immunophenotyping ; Mice ; Mice, Transgenic ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/mortality ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Thymocytes/pathology ; Transcriptome

المؤلفون: Das B; Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, California. dfelsher@stanford.edu bdas@kavikrishnalab.org.; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Experimental Therapeutics, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, Massachusetts.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts., Pal B; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Experimental Therapeutics, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, Massachusetts.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts., Bhuyan R; Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, California.; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Experimental Therapeutics, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, Massachusetts.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts., Li H; Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, California.; Department of Experimental Therapeutics, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, Massachusetts.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts., Sarma A; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Dr. B. Borooah Cancer Institute, Guwahati, Assam, India., Gayan S; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Experimental Therapeutics, Thoreau Laboratory for Global Health, M2D2, University of Massachusetts, Lowell, Massachusetts.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts., Talukdar J; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India., Sandhya S; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India., Bhuyan S; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India., Gogoi G; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Immunology and Infectious Diseases, Forsyth Institute, Cambridge, Massachusetts.; Department of Pathology, Assam Medical College, Dibrugarh, Assam, India., Gouw AM; Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, California., Baishya D; Department of Cancer and Stem Cell Biology, KaviKrishna Laboratory, Guwahati Biotech Park, Indian Institute of Technology, Guwahati, Assam, India.; Department of Bioengineering and Technology, Gauhati University, Guwahati, Assam, India., Gotlib JR; Division of Hematology, Stanford Cancer Institute, Stanford, California., Kataki AC; Dr. B. Borooah Cancer Institute, Guwahati, Assam, India., Felsher DW; Division of Oncology, Departments of Medicine and Pathology, Stanford University School of Medicine, Stanford, California. dfelsher@stanford.edu bdas@kavikrishnalab.org.

المصدر: Cancer research [Cancer Res] 2019 Aug 15; Vol. 79 (16), pp. 4015-4025. Date of Electronic Publication: 2019 Jul 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*metabolism , Nanog Homeobox Protein/*metabolism , Neoplastic Stem Cells/*pathology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*pathology , Proto-Oncogene Proteins c-myc/*genetics , SOXB1 Transcription Factors/*metabolism, ATP Binding Cassette Transporter, Subfamily G, Member 2/genetics ; ATP Binding Cassette Transporter, Subfamily G, Member 2/metabolism ; Animals ; Antigens, Ly/genetics ; Antigens, Ly/metabolism ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Gene Expression Regulation, Neoplastic ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, SCID ; Mice, Transgenic ; Nanog Homeobox Protein/genetics ; Neoplasm Proteins/genetics ; Neoplasm Proteins/metabolism ; Neoplastic Stem Cells/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Promoter Regions, Genetic ; Proto-Oncogene Proteins c-myc/metabolism ; Reactive Oxygen Species/metabolism ; SOXB1 Transcription Factors/genetics ; Xenograft Model Antitumor Assays

المؤلفون: Shu Y; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Molecular Oncology Laboratory, Departments of Surgery and Orthopaedic Surgery, The University of Chicago Medical Center, Chicago, Illinois., Wang Y; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Lv WQ; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Peng DY; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Li J; Institute of Biochemistry and Cell Biochemistry, Shanghai Institute of Biomedical Sciences, Shanghai, China., Zhang H; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Jiang GJ; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Yang BJ; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Liu S; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Zhang J; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Chen YH; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Tang S; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Wan KX; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Yuan JT; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Guo W; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Fu G; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Qi XK; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Liu ZD; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Liu HY; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Department of Hematology, The Children's Hospital of Chongqing Medical University, Chongqing, China., Yang C; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Molecular Oncology Laboratory, Departments of Surgery and Orthopaedic Surgery, The University of Chicago Medical Center, Chicago, Illinois., Zhang LH; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Molecular Oncology Laboratory, Departments of Surgery and Orthopaedic Surgery, The University of Chicago Medical Center, Chicago, Illinois., Liu FJ; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China., Yu J; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Department of Hematology, The Children's Hospital of Chongqing Medical University, Chongqing, China., Zhang PH; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.; Clinical Laboratory Center, The Children's Hospital of Chongqing Medical University, Chongqing, China., Qu B; Department of Biophysics, Center for Integrative Physiology and Molecular Medicine, School of Medicine, Saarland University, Homburg, Germany., Zhao H; School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China., He TC; Molecular Oncology Laboratory, Departments of Surgery and Orthopaedic Surgery, The University of Chicago Medical Center, Chicago, Illinois. zoulin74@126.com tche@uchicago.edu., Zou L; Center for Clinical Molecular Medicine, The Children's Hospital of Chongqing Medical University, Chongqing, China. zoulin74@126.com tche@uchicago.edu.; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Chongqing, China.; Key Laboratory of Pediatrics in Chongqing, Chongqing Stem Cell Therapy Engineering Center, Chongqing, China.

المصدر: Cancer research [Cancer Res] 2020 Mar 01; Vol. 80 (5), pp. 988-998. Date of Electronic Publication: 2019 Dec 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs/*metabolism , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics , Receptor, Notch1/*metabolism , Tumor Suppressor Proteins/*genetics , beta-Arrestin 1/*genetics, 3' Untranslated Regions/genetics ; Adolescent ; Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Child ; Child, Preschool ; Female ; Gene Expression Regulation, Leukemic ; Humans ; Male ; Mice ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Proteolysis ; RNA-Seq ; Signal Transduction/genetics ; Tumor Suppressor Proteins/metabolism ; Xenograft Model Antitumor Assays ; beta-Arrestin 1/metabolism

المؤلفون: Ross J; Institut de recherches cliniques de Montréal (IRCM), Hematopoiesis and Cancer Unit, Montréal, Quebec, Canada., Rashkovan M; Institut de recherches cliniques de Montréal (IRCM), Hematopoiesis and Cancer Unit, Montréal, Quebec, Canada., Fraszczak J; Institut de recherches cliniques de Montréal (IRCM), Hematopoiesis and Cancer Unit, Montréal, Quebec, Canada., Joly-Beauparlant C; Bioinformatic Platform, Faculty of Medicine, Université Laval, Québec, Canada., Vadnais C; Institut de recherches cliniques de Montréal (IRCM), Hematopoiesis and Cancer Unit, Montréal, Quebec, Canada., Winkler R; Department of Biochemistry, Aging Research Center (ARC), Friedrich-Schiller-University Jena, Jena, Germany., Droit A; Bioinformatic Platform, Faculty of Medicine, Université Laval, Québec, Canada., Kosan C; Department of Biochemistry, Aging Research Center (ARC), Friedrich-Schiller-University Jena, Jena, Germany., Möröy T; Institut de recherches cliniques de Montréal (IRCM), Hematopoiesis and Cancer Unit, Montréal, Quebec, Canada. Tarik.Moroy@ircm.qc.ca.; Department of Microbiology, Immunology, and Infectiology, Université de Montréal, Montréal, Quebec, Canada.

المصدر: Cancer research [Cancer Res] 2019 Aug 15; Vol. 79 (16), pp. 4184-4195. Date of Electronic Publication: 2019 Jul 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Cytarabine/*pharmacology , Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Protein Inhibitors of Activated STAT/*genetics , Ubiquitin-Protein Ligases/*genetics, Animals ; Antimetabolites, Antineoplastic/pharmacology ; Female ; Gene Expression Regulation, Neoplastic ; Genes, myc ; Mice, Transgenic ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Protein Domains ; Protein Inhibitors of Activated STAT/metabolism ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Ubiquitin-Protein Ligases/metabolism

المؤلفون: Sulima SO; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Kampen KR; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Vereecke S; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Pepe D; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Fancello L; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Verbeeck J; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium., Dinman JD; Department of Cell Biology and Molecular Genetics, University of Maryland, College Park, Maryland., De Keersmaecker K; Department of Oncology, KU Leuven, LKI - Leuven Cancer Institute, Leuven, Belgium. kim.dekeersmaecker@kuleuven.be.

المصدر: Cancer research [Cancer Res] 2019 Jan 15; Vol. 79 (2), pp. 320-327. Date of Electronic Publication: 2018 Nov 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics , Ribosomes/*genetics, Animals ; Cell Line, Tumor ; Cell Proliferation/genetics ; Humans ; Male ; Mice ; Mice, Transgenic ; Mutagenesis ; Mutation ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; Ribosomal Protein L10 ; Ribosomal Proteins/genetics ; Ribosomal Proteins/metabolism ; Ribosomes/metabolism ; Ribosomes/pathology

المؤلفون: Yang F; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Feng W; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Wang H; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Wang L; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Liu X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Wang R; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Chen C; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Yang X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Zhang D; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Ren Q; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China., Zheng G; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China. zhengggtjchn@aliyun.com.

المصدر: Cancer research [Cancer Res] 2020 Sep 01; Vol. 80 (17), pp. 3677-3691. Date of Electronic Publication: 2020 Jul 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Macrophages/*immunology , Macrophages/*pathology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*immunology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*pathology, Animals ; Mice ; Mice, Knockout ; Monocytes/immunology ; Monocytes/pathology

المؤلفون: Rao SS; Merck Research Laboratories, Boston, Massachusetts 02115, USA., O'Neil J, Liberator CD, Hardwick JS, Dai X, Zhang T, Tyminski E, Yuan J, Kohl NE, Richon VM, Van der Ploeg LH, Carroll PM, Draetta GF, Look AT, Strack PR, Winter CG

المصدر: Cancer research [Cancer Res] 2009 Apr 01; Vol. 69 (7), pp. 3060-8. Date of Electronic Publication: 2009 Mar 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid Precursor Protein Secretases/*antagonists & inhibitors , Cyclic S-Oxides/*pharmacology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*metabolism , Protease Inhibitors/*pharmacology , Receptor, Notch1/*antagonists & inhibitors , Retinoblastoma Protein/*metabolism , Thiadiazoles/*pharmacology, Cell Line, Tumor ; Cyclin-Dependent Kinase 4/antagonists & inhibitors ; Cyclin-Dependent Kinase Inhibitor p19/biosynthesis ; Cyclin-Dependent Kinase Inhibitor p27 ; G1 Phase/drug effects ; G1 Phase/genetics ; Gene Expression Profiling ; Humans ; Intracellular Signaling Peptides and Proteins/metabolism ; Phosphorylation ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Receptor, Notch1/genetics ; Receptor, Notch1/metabolism ; S Phase/drug effects ; S Phase/genetics ; Signal Transduction/drug effects ; Transcription, Genetic ; Transfection

المؤلفون: Silva A; Instituto de Medicina Molecular, Faculdade de Medicina da Univer, Lisbon, Portugal., Laranjeira AB, Martins LR, Cardoso BA, Demengeot J, Yunes JA, Seddon B, Barata JT

المصدر: Cancer research [Cancer Res] 2011 Jul 15; Vol. 71 (14), pp. 4780-9. Date of Electronic Publication: 2011 May 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Interleukin-7/*metabolism , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*pathology, Animals ; Cell Growth Processes/physiology ; Cell Survival/physiology ; Cyclin-Dependent Kinase Inhibitor p27/metabolism ; Disease Models, Animal ; Disease Progression ; Down-Regulation ; Humans ; Interleukin-7/blood ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Receptors, Interleukin-7/biosynthesis ; Receptors, Interleukin-7/genetics ; Transplantation, Heterologous ; Tumor Microenvironment ; Up-Regulation

المؤلفون: Appert A; Medical Research Council Laboratory of Molecular Biology, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom., Nam CH, Lobato N, Priego E, Miguel RN, Blundell T, Drynan L, Sewell H, Tanaka T, Rabbitts T

المصدر: Cancer research [Cancer Res] 2009 Jun 01; Vol. 69 (11), pp. 4784-90.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Validation Study

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Aptamers, Peptide/*pharmacology , DNA-Binding Proteins/*antagonists & inhibitors , DNA-Binding Proteins/*physiology , Drug Delivery Systems/*methods , Metalloproteins/*antagonists & inhibitors , Metalloproteins/*physiology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*genetics, Adaptor Proteins, Signal Transducing ; Amino Acid Sequence ; Animals ; Aptamers, Peptide/metabolism ; Aptamers, Peptide/therapeutic use ; CHO Cells ; Cricetinae ; Cricetulus ; DNA-Binding Proteins/genetics ; DNA-Binding Proteins/metabolism ; Humans ; LIM Domain Proteins ; Metalloproteins/genetics ; Metalloproteins/metabolism ; Mice ; Mice, Transgenic ; Models, Molecular ; Molecular Sequence Data ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Protein Binding/genetics ; Protein Interaction Domains and Motifs/genetics ; Tumor Cells, Cultured ; Zinc Fingers/genetics ; Zinc Fingers/physiology

المؤلفون: Chiarini F; Department of Human Anatomy, University of Bologna, Bologna, Italy., Grimaldi C, Ricci F, Tazzari PL, Evangelisti C, Ognibene A, Battistelli M, Falcieri E, Melchionda F, Pession A, Pagliaro P, McCubrey JA, Martelli AM

المصدر: Cancer research [Cancer Res] 2010 Oct 15; Vol. 70 (20), pp. 8097-107. Date of Electronic Publication: 2010 Sep 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Imidazoles/*therapeutic use , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Quinolines/*therapeutic use, Animals ; Antineoplastic Agents/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Apoptosis/drug effects ; Autophagy/drug effects ; Cell Cycle/drug effects ; Cell Division/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Coculture Techniques ; Flow Cytometry ; Humans ; Jurkat Cells/drug effects ; Mice ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Stromal Cells/drug effects