المؤلفون: Mingyang Shao, Qing Xu, Menglin Chen, Xiaoyue Cao, Chuan Li, Hong Bu, Yuwei Chen, Yuke Shu, Zhenru Wu, Gang Guo, Yuping Gong, Yongjie Zhou, Yujun Shi

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 633-651 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Adenosine, FoxM1, forkhead box M1, IRE1α, inositol requiring enzyme 1 alpha, XBP1, X-box-binding protein 1, STAT, signal transducers and activators of transcription, RNA Stability, Mettl3, methyltransferase-like 3, Alkbh5, ALKB family member 5 protein, Apoptosis, RC799-869, AST, aspartate aminotransferase, WTAP, Wilms’ tumor 1-associated protein, Endoplasmic Reticulum, UPR, unfolded protein response, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Homeostasis, TUDCA, tauroursodeoxycholate, BrdU, 5-bromo-2-deoxyuridine, eIF2α, eukaryotic translation initiator factor 2α, Original Research, Mice, Knockout, N6-methyladenosine, Chemistry, Gastroenterology, PI3K, phosphatidylinositol 3-kinase, Methylation, Diseases of the digestive system. Gastroenterology, Cell cycle, Endoplasmic Reticulum Stress, Liver regeneration, Cell biology, UTR, untranslated region, medicine.anatomical_structure, Liver, PHx, partial hepatectomy, Organ Specificity, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, FTO, fat mass and obesity-associated protein, ATF6, activating transcription factor 6, AMPK, adenosine 5′-monophosphate-activated protein kinase, JAK, janus kinase, ER, endoplasmic reticulum, Taurochenodeoxycholic Acid, PAS, periodic acid–Schiff, Necrosis, 03 medical and health sciences, ALT, alanine aminotransferase, TM, tunicamycin, medicine, Act D, actinomycin, Animals, Hepatectomy, RNA, Messenger, Cell Proliferation, Messenger RNA, Hepatology, Endoplasmic reticulum, CDS, coding sequence, Mettl14, Methyltransferases, FC, fold change, m6A, N6-methyladenosine, WT, wild-type, Liver Regeneration, m6A-seq, m6A sequencing, 030104 developmental biology, MRNA Sequencing, Hepatocytes, Unfolded protein response, EIF3A, eukaryotic translation initiation factor 3 subunit A, HCC, hepatocellular carcinoma, Peptides, Transcriptome, PERK, protein kinase R-like endoplasmic reticulum kinase, Chop, C/EBP-homologous protein, MAPK, mitogen-activated protein kinase, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07948b84c6263e6b798b7056d5735a81
https://doi.org/10.1016/j.jcmgh.2021.04.001

المؤلفون: Adolfo Odriozola, Mariana Castro Dias, Daniel Candinas, Tural Yarahmadov, Fadi Jebbawi, Mikio Furuse, Benoît Zuber, Alex Odermatt, Cristina Gómez Castellà, Urban Deutsch, Adrian Keogh, Riccardo Tombolini, Deborah Stroka, Britta Engelhardt, Daniel Sánchez-Taltavull, Felix Alexander Baier

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 745-767 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Baier, Felix Alexander; Sánchez-Taltavull, Daniel; Yarahmadov, Tural; Castellà, Cristina Gómez; Jebbawi, Fadi; Keogh, Adrian; Tombolini, Riccardo; Odriozola, Adolfo; Castro Dias, Mariana; Deutsch, Urban; Furuse, Mikio; Engelhardt, Britta; Zuber, Benoît; Odermatt, Alex; Candinas, Daniel; Keogh-Stroka, Deborah M. (2021). Loss of claudin-3 impairs hepatic metabolism, biliary barrier function and cell proliferation in the murine liver. Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745-767. Elsevier 10.1016/j.jcmgh.2021.04.003 <http://dx.doi.org/10.1016/j.jcmgh.2021.04.003>

مصطلحات موضوعية: 0301 basic medicine, Aging, Muricholic acid, RC799-869, Single-Cell RNA Sequencing, chemistry.chemical_compound, 0302 clinical medicine, Claudin-3, UMI, unique molecular identifiers, Original Research, Mice, Knockout, scRNA-seq, single-cell RNA sequencing, CA, cholic acid, Bile acid, Tight junction, Tight Junction, Chemistry, Liver cell, Gastroenterology, Diseases of the digestive system. Gastroenterology, mRNA, messenger RNA, Liver regeneration, 3. Good health, Cell biology, TJ, tight junction, medicine.anatomical_structure, Liver, PHx, partial hepatectomy, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, Bile Acid, ALT, alanine-aminotransferase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, Taurochenodeoxycholic acid, 610 Medicine & health, Tight Junctions, 03 medical and health sciences, medicine, Animals, Hepatectomy, Claudin, Cell Proliferation, ALP, alkaline phosphatase, Hepatology, Gene Expression Profiling, pHH3, phosphohistone H3, Lipid Metabolism, Liver Regeneration, Mice, Inbred C57BL, 030104 developmental biology, Gene Expression Regulation, Hepatocytes, AST, aspartate-aminotransferase, 570 Life sciences, biology, Bile Ducts, Gene Deletion, DAPI, 4′,6-diamidino-2-phenylindole

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bffc6cf475451c7410cb92d0d752071
https://doi.org/10.1016/j.jcmgh.2021.04.003