المؤلفون: Dakota R. Robarts, Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy, Norman Lee, Hartmut Jaeschke, Sumedha Gunewardena, Stephen A. Whelan, John A. Hanover, Natasha E. Zachara, Chad Slawson, Udayan Apte

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 5, Pp 1510-1529 (2022)

مصطلحات موضوعية: Cell Death, HNF4alpha, Proliferation, Partial Hepatectomy, Regeneration, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X22000145; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/ea3c4596c6654707b658a0f0be83e403

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المؤلفون: Mingyang Shao, Qing Xu, Menglin Chen, Xiaoyue Cao, Chuan Li, Hong Bu, Yuwei Chen, Yuke Shu, Zhenru Wu, Gang Guo, Yuping Gong, Yongjie Zhou, Yujun Shi

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 633-651 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Adenosine, FoxM1, forkhead box M1, IRE1α, inositol requiring enzyme 1 alpha, XBP1, X-box-binding protein 1, STAT, signal transducers and activators of transcription, RNA Stability, Mettl3, methyltransferase-like 3, Alkbh5, ALKB family member 5 protein, Apoptosis, RC799-869, AST, aspartate aminotransferase, WTAP, Wilms’ tumor 1-associated protein, Endoplasmic Reticulum, UPR, unfolded protein response, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, Homeostasis, TUDCA, tauroursodeoxycholate, BrdU, 5-bromo-2-deoxyuridine, eIF2α, eukaryotic translation initiator factor 2α, Original Research, Mice, Knockout, N6-methyladenosine, Chemistry, Gastroenterology, PI3K, phosphatidylinositol 3-kinase, Methylation, Diseases of the digestive system. Gastroenterology, Cell cycle, Endoplasmic Reticulum Stress, Liver regeneration, Cell biology, UTR, untranslated region, medicine.anatomical_structure, Liver, PHx, partial hepatectomy, Organ Specificity, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, FTO, fat mass and obesity-associated protein, ATF6, activating transcription factor 6, AMPK, adenosine 5′-monophosphate-activated protein kinase, JAK, janus kinase, ER, endoplasmic reticulum, Taurochenodeoxycholic Acid, PAS, periodic acid–Schiff, Necrosis, 03 medical and health sciences, ALT, alanine aminotransferase, TM, tunicamycin, medicine, Act D, actinomycin, Animals, Hepatectomy, RNA, Messenger, Cell Proliferation, Messenger RNA, Hepatology, Endoplasmic reticulum, CDS, coding sequence, Mettl14, Methyltransferases, FC, fold change, m6A, N6-methyladenosine, WT, wild-type, Liver Regeneration, m6A-seq, m6A sequencing, 030104 developmental biology, MRNA Sequencing, Hepatocytes, Unfolded protein response, EIF3A, eukaryotic translation initiation factor 3 subunit A, HCC, hepatocellular carcinoma, Peptides, Transcriptome, PERK, protein kinase R-like endoplasmic reticulum kinase, Chop, C/EBP-homologous protein, MAPK, mitogen-activated protein kinase, Gene Deletion

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07948b84c6263e6b798b7056d5735a81
https://doi.org/10.1016/j.jcmgh.2021.04.001

المؤلفون: Adolfo Odriozola, Mariana Castro Dias, Daniel Candinas, Tural Yarahmadov, Fadi Jebbawi, Mikio Furuse, Benoît Zuber, Alex Odermatt, Cristina Gómez Castellà, Urban Deutsch, Adrian Keogh, Riccardo Tombolini, Deborah Stroka, Britta Engelhardt, Daniel Sánchez-Taltavull, Felix Alexander Baier

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 745-767 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Baier, Felix Alexander; Sánchez-Taltavull, Daniel; Yarahmadov, Tural; Castellà, Cristina Gómez; Jebbawi, Fadi; Keogh, Adrian; Tombolini, Riccardo; Odriozola, Adolfo; Castro Dias, Mariana; Deutsch, Urban; Furuse, Mikio; Engelhardt, Britta; Zuber, Benoît; Odermatt, Alex; Candinas, Daniel; Keogh-Stroka, Deborah M. (2021). Loss of claudin-3 impairs hepatic metabolism, biliary barrier function and cell proliferation in the murine liver. Cellular and molecular gastroenterology and hepatology, 12(2), pp. 745-767. Elsevier 10.1016/j.jcmgh.2021.04.003 <http://dx.doi.org/10.1016/j.jcmgh.2021.04.003>

مصطلحات موضوعية: 0301 basic medicine, Aging, Muricholic acid, RC799-869, Single-Cell RNA Sequencing, chemistry.chemical_compound, 0302 clinical medicine, Claudin-3, UMI, unique molecular identifiers, Original Research, Mice, Knockout, scRNA-seq, single-cell RNA sequencing, CA, cholic acid, Bile acid, Tight junction, Tight Junction, Chemistry, Liver cell, Gastroenterology, Diseases of the digestive system. Gastroenterology, mRNA, messenger RNA, Liver regeneration, 3. Good health, Cell biology, TJ, tight junction, medicine.anatomical_structure, Liver, PHx, partial hepatectomy, Hepatocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, Bile Acid, ALT, alanine-aminotransferase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, Taurochenodeoxycholic acid, 610 Medicine & health, Tight Junctions, 03 medical and health sciences, medicine, Animals, Hepatectomy, Claudin, Cell Proliferation, ALP, alkaline phosphatase, Hepatology, Gene Expression Profiling, pHH3, phosphohistone H3, Lipid Metabolism, Liver Regeneration, Mice, Inbred C57BL, 030104 developmental biology, Gene Expression Regulation, Hepatocytes, AST, aspartate-aminotransferase, 570 Life sciences, biology, Bile Ducts, Gene Deletion, DAPI, 4′,6-diamidino-2-phenylindole

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bffc6cf475451c7410cb92d0d752071
https://doi.org/10.1016/j.jcmgh.2021.04.003

المؤلفون: Yanjun Jiang, Meenasri Kumbaji, Amber M. D'Souza, Sheeniza Shah, Leila Valanejad, Ashley Cast, Rebekah Karns, Mary Wright, David B. Smithrud, Soona Shin, Kyle Lewis, Nikolai A. Timchenko

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 3, Pp 239-255 (2018)

مصطلحات موضوعية: Hepatoblastoma, Male, 0301 basic medicine, Tumor-Suppressor Proteins, Gankyrin, Proliferation, C/EBP, CCAAT/enhancer binding protein, GLKO, Gankyrin liver-specific knock-out, BrdU, bromodeoxyuridine, Mice, Genes, Tumor Suppressor, Rb, retinoblastoma, Carbon Tetrachloride, Original Research, Cancer, Mice, Knockout, Liver injury, Benzenesulfonates, Liver Neoplasms, Gastroenterology, Progenitor Cells, Opn, osteopontin, mRNA, messenger RNA, 3. Good health, Gene Expression Regulation, Neoplastic, Editorial, medicine.anatomical_structure, Liver, Hepatocyte, Liver cancer, RT-PCR, reverse-transcriptase polymerase chain reaction, Carcinoma, Hepatocellular, PH, partial hepatectomy, PCNA, proliferating cell nuclear antigen, Down-Regulation, Protein degradation, Biology, LKO, liver-specific knock-out, HNF4α, hepatocyte nuclear factor 4α, cDNA, complementary DNA, 03 medical and health sciences, FXR, farnesoid X receptor, UPS, ubiquitin proteasome system, TSP, tumor-suppressor protein, Cell Line, Tumor, medicine, Animals, Humans, lcsh:RC799-869, CUGBP1, CUG triplet repeat binding protein 1, Cell Proliferation, Hepatology, Oncogene, Tumor Suppressor Proteins, Triazoles, medicine.disease, WT, wild-type, MicroRNAs, 030104 developmental biology, 2D, 2-dimensional, Cancer cell, Hepatocytes, Cancer research, biology.protein, lcsh:Diseases of the digestive system. Gastroenterology, Gank, Gankyrin, HCC, hepatocellular carcinoma, Co-IP, co-immunoprecipitation, Transcription Factors, DEN, diethylnitrosamine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a827d10be77fd53d2b878a033f12355
https://doi.org/10.1016/j.jcmgh.2018.05.007

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المؤلفون: D'Souza AM; Department of Oncology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Jiang Y; Huffington Center on Aging, Baylor College of Medicine, Houston, Texas., Cast A; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Valanejad L; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Wright M; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Lewis K; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Kumbaji M; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Shah S; Department of Chemistry, University of Cincinnati, Cincinnati, Ohio., Smithrud D; Department of Chemistry, University of Cincinnati, Cincinnati, Ohio., Karns R; Department of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Shin S; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio., Timchenko N; Department of Surgery, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

المصدر: Cellular and molecular gastroenterology and hepatology [Cell Mol Gastroenterol Hepatol] 2018 May 24; Vol. 6 (3), pp. 239-255. Date of Electronic Publication: 2018 May 24 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Gastroenterological Association Country of Publication: United States NLM ID: 101648302 Publication Model: eCollection Cited Medium: Internet ISSN: 2352-345X (Electronic) Linking ISSN: 2352345X NLM ISO Abbreviation: Cell Mol Gastroenterol Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular/*pathology , Hepatoblastoma/*pathology , Hepatocytes/*pathology , Liver Neoplasms/*pathology , Transcription Factors/*metabolism , Tumor Suppressor Proteins/*metabolism, Animals ; Benzenesulfonates/pharmacology ; Carbon Tetrachloride/pharmacology ; Carcinoma, Hepatocellular/metabolism ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Hepatoblastoma/metabolism ; Hepatocytes/drug effects ; Humans ; Liver Neoplasms/metabolism ; Male ; Mice ; Mice, Knockout ; Transcription Factors/genetics ; Triazoles/pharmacology