المؤلفون: Stefan L. Zimmerman, Joao A.C. Lima, Hugh Calkins, Irfan M. Khurram, Hiroshi Ashikaga, Saman Nazarian, Vadim Zipunnikov, Kotaro Fukumoto, Mohammadali Habibi, John Rickard, Joseph E. Marine, David D. Spragg

المصدر: Circulation: Cardiovascular Imaging. 8

مصطلحات موضوعية: medicine.medical_specialty, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Magnetic resonance imaging, Atrial fibrillation, Strain rate, medicine.disease, Ablation, Fibrosis, Internal medicine, Predictive value of tests, medicine, Cardiology, Radiology, Nuclear Medicine and imaging, Sinus rhythm, Cardiology and Cardiovascular Medicine, business, Chi-squared distribution

الوصف: Background— Atrial fibrillation (AF) is associated with left atrial (LA) structural and functional changes. Cardiac magnetic resonance late gadolinium enhancement (LGE) and feature-tracking are capable of noninvasive quantification of LA fibrosis and myocardial motion, respectively. We sought to examine the association of phasic LA function with LA enhancement in patients with AF. Methods and Results— LA structure and function was measured in 90 patients with AF (age 61±10 years; 76% men) referred for ablation and 14 healthy volunteers. Peak global longitudinal LA strain, LA systolic strain rate, and early and late diastolic strain rates were measured using cine–cardiac magnetic resonance images acquired during sinus rhythm. The degree of LGE was quantified. Compared with patients with paroxysmal AF (60% of cohort), those with persistent AF had larger maximum LA volume index (56±17 versus 49±13 mL/m 2 ; P =0.036), and increased LGE (27.1±11.7% versus 36.8±14.8%; P P P P Conclusions— Increased LA enhancement is associated with decreased LA reservoir, conduit, and booster pump functions. Phasic measurement of LA function using feature-tracking cardiac magnetic resonance may add important information about the physiological importance of LA fibrosis.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b385f9037af71abe45ded2635ed7398d
https://doi.org/10.1161/circimaging.114.002769