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1
المؤلفون: M. Cayón-Blanco, C. García-Figueras-Mateos
المصدر: Clinical Nutrition. 38:S164-S165
مصطلحات موضوعية: Pediatrics, medicine.medical_specialty, Nutrition and Dietetics, Quality of life (healthcare), business.industry, Weight loss, Medicine, medicine.symptom, Critical Care and Intensive Care Medicine, business
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2
المؤلفون: C. García-Figueras-Mateos, M. Cayón-Blanco
المصدر: Clinical Nutrition. 37:S167
مصطلحات موضوعية: Glycosuria, medicine.medical_specialty, Energy loss, Nutrition and Dietetics, business.industry, Type 2 Diabetes Mellitus, Critical Care and Intensive Care Medicine, chemistry.chemical_compound, Endocrinology, chemistry, Weight loss, Internal medicine, medicine, Dapagliflozin, medicine.symptom, business
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3
المؤلفون: Maite Figueras, Gemma Fuster, Sílvia Busquets, Francisco J. López-Soriano, Josep M. Argilés, Paola Costelli, Neus Carbó, Mireia Olivan, Elisabet Ametller
المصدر: Clinical Nutrition. 26:239-244
مصطلحات موضوعية: Male, medicine.medical_specialty, Cachexia, Muscle Proteins, Resveratrol, Protein degradation, Critical Care and Intensive Care Medicine, Carcinoma, Lewis Lung, Mice, Random Allocation, chemistry.chemical_compound, Fish Oils, In vivo, Internal medicine, Stilbenes, Animals, Medicine, Rats, Wistar, Muscle, Skeletal, Sarcoma, Yoshida, Wasting, Nutrition and Dietetics, business.industry, Body Weight, NF-kappa B, Skeletal muscle, Lewis lung carcinoma, Neoplasms, Experimental, Organ Size, medicine.disease, Rats, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, chemistry, Biochemistry, Docosahexaenoic acid, medicine.symptom, Energy Intake, business
الوصف: Summary Background & aims Resveratrol has been reported to have antitumoural effects and recently it has been demonstrated that resveratrol partially blocks skeletal muscle wasting by interfering with NF- κ B activation. We decided to investigate the potential anti-wasting properties of resveratrol on different models of cancer cachexia in experimental animals. Methods and results Incubations of isolated extensor digitorum longus muscles in the presence of 30μM of resveratrol caused a significant decrease in the rate of protein degradation. However, administration of resveratrol in vivo to both rats bearing the Yoshida AH-130 ascites hepatoma (at the dose of 1mg/kg body weight) and mice bearing the Lewis lung carcinoma (at two different doses, 5 and 25mg/kg body weight) had no effect on skeletal muscle mass or body weight in tumour-bearing rodents. In addition, a combination of resveratrol (3mg/kg body weight) and fish oil was also unable to induce any changes in skeletal muscle weights. Conclusions It is therefore concluded from this study that resveratrol is unable to influence muscle mass in vivo and has no potential role as anticachectic agent for the treatment of muscle wasting associated with tumour growth.
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4
المؤلفون: M. Cayón, C. García-Figueras, M. Serrano
المصدر: Clinical Nutrition. 33:S61-S62
مصطلحات موضوعية: medicine.medical_specialty, Nutrition and Dietetics, business.industry, Cancer, Nutritional status, Critical Care and Intensive Care Medicine, medicine.disease, Dysphagia, Internal medicine, medicine, Physical therapy, In patient, medicine.symptom, Association (psychology), business
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5
المؤلفون: A. Rafecas-Renau, F. Pi-Siques, A. Sitges-Serra, P. Puig-Gris, A. Bianchi-Cardona, J. Colomer, J. Figueras-Felip
المصدر: Clinical Nutrition. 5:117-121
مصطلحات موضوعية: medicine.medical_specialty, Nitrogen balance, Nutrition and Dietetics, business.industry, medicine.medical_treatment, Critical Care and Intensive Care Medicine, Blood proteins, Surgery, law.invention, Regimen, Parenteral nutrition, Randomized controlled trial, Weight loss, law, medicine, medicine.symptom, Elective surgery, business, Saline
الوصف: To study the potential benefits of hypocaloric peripheral parenteral nutrition (HPPN) in medium to high risk surgical patients we compared this regimen with standard fluid therapy during the postoperative period. Seventy patients were randomised to receive HPPN, consisting of 1 g of amino acids and 2 g of polyols (sorbitol and xylitol) per Kg per day (n = 41), or 1500 ml of 5% glucose and 1500 ml of saline (n = 29). There were no differences in length of hospital stay, postoperative complications or weight loss between the two groups. Concentrations of short and long half-life plasma proteins were similar in both groups. Nitrogen balance was negative and the nitrogen retention was low (60%) in the HPPN group. We conclude that there are no discernible clinical advantages in giving HPPN postoperatively to patients undergoing medium or major severity elective surgery.