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المؤلفون: James A. Pearson, F. Susan Wong, Joanne Davies, Stephanie J. Hanna, Li Wen, Terri C. Thayer
المصدر: Diabetes. 70:529-537
مصطلحات موضوعية: 0301 basic medicine, Stromal cell, biology, Chemistry, Endocrinology, Diabetes and Metabolism, Peripheral tolerance, CD28, 030209 endocrinology & metabolism, Major histocompatibility complex, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Internal Medicine, biology.protein, Lymph node stromal cell, Cancer research, Cytotoxic T cell, CD8, Proinsulin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::379f334a990a8f4d80e1856c38585319
https://doi.org/10.2337/db19-1050 -
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المؤلفون: Josephine H. Li, Jose C. Florez, Ewan R. Pearson, Adem Y. Dawed, Lukasz Szczerbinski, Varinderpal Kaur, Jennifer N. Todd
المصدر: Diabetes
مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Genotype, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Genome-wide association study, Type 2 diabetes, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Internal Medicine, Humans, Hypoglycemic Agents, Medicine, Genetic Predisposition to Disease, Glycemic, Glycated Hemoglobin, business.industry, Insulin, nutritional and metabolic diseases, Genetics/Genomes/Proteomics/Metabolomics, medicine.disease, 3. Good health, Metformin, Sulfonylurea Compounds, Treatment Outcome, 030104 developmental biology, Diabetes Mellitus, Type 2, Pharmacogenetics, Female, business, Genome-Wide Association Study, Glipizide, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f42d08d38146e4bceda77275033fc3b
https://doi.org/10.2337/db20-0530 -
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المؤلفون: Sook Wah Yee, Skylar W. Marvel, Hetal Shah, Tammy M. Havener, Michiaki Kubo, MetGen Investigators, John B. Buse, Accord, He Gao, Alessandro Doria, Kaixin Zhou, Monique M. Hedderson, Ewan R. Pearson, Mark A. Herman, ACCORDion Investigators, John Jack, Josyf C. Mychaleckyi, Kathleen M. Giacomini, Howard L. McLeod, Michael J. Wagner, Alison A. Motsinger-Reif, Daniel M. Rotroff
المصدر: Diabetes. 67:1428-1440
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, PRPF31, endocrine system diseases, Endocrinology, Diabetes and Metabolism, Type 2 diabetes, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Diabetes mellitus, Internal Medicine, Medicine, business.industry, Genetic variants, nutritional and metabolic diseases, Total body, medicine.disease, 3. Good health, Metformin, Clinical trial, 030104 developmental biology, Endocrinology, 030220 oncology & carcinogenesis, Knockout mouse, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a0f29570193e2168220a458852d8f26b
https://doi.org/10.2337/db17-1164 -
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المؤلفون: Tracy D. Vozheiko, Malathi Kandarpa, Scott A. Soleimanpour, Gemma L. Pearson, Biaoxin Chai, Xueying Liu, Robert C. Piper
المصدر: Diabetes
مصطلحات موضوعية: 0301 basic medicine, biology, Ubiquitin, Chemistry, Effector, Mitochondrial Turnover, Ubiquitin-Protein Ligases, Endocrinology, Diabetes and Metabolism, Mitophagy, Mitochondrion, Mitochondria, Cell biology, Deubiquitinating enzyme, Ubiquitin ligase, 03 medical and health sciences, 030104 developmental biology, Mediator, Islet Studies, Insulin Secretion, Autophagy, Internal Medicine, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5226a6549a550e3509b98f4a6f843a2e
https://doi.org/10.2337/db17-0321 -
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المؤلفون: David Price, Terri C. Thayer, Dimitri Kakabadse, F. Susan Wong, Joanne Davies, James E. McLaren, Peter Huw Morgan, Kristin Ladell, James A. Pearson, Li Wen, Evy De Leenheer, Amy Phillips, Kelly L. Miners
المصدر: Diabetes
مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, Receptors, Antigen, T-Cell, alpha-beta, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, T cell, Antibody Affinity, Mice, Transgenic, CD8-Positive T-Lymphocytes, Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Antigen, Mice, Inbred NOD, Internal Medicine, medicine, Animals, Insulin, Cytotoxic T cell, Proinsulin, NOD mice, T-cell receptor, R1, Cell biology, Diabetes Mellitus, Type 1, 030104 developmental biology, medicine.anatomical_structure, Immunology, Immunology and Transplantation, CD8, 030215 immunology
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6e8d51cc0e444193b985867b1a1620
https://doi.org/10.2337/db15-1498 -
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المؤلفون: Anna Murray, Francesca Frau, Dennis O. Mook-Kanamori, Samuel E. Jones, Andrianos M. Yiorkas, Michael N. Weedon, Rachel M. Freathy, Andrew R. Wood, Andrew T. Hattersley, Ewan R. Pearson, Harald Staiger, Hanieh Yaghootkar, Robin N Beaumont, Caroline Hayward, Marcus A. Tuke, Alexandra I. F. Blakemore, Hans-Ulrich Häring, Norbert Stefan, Renée de Mutsert, Anubha Mahajan, Archie Campbell, Timothy M. Frayling, Jessica Tyrrell, Jürgen Machann, Karla V. Allebrandt, Yingjie Ji, Jimmy D. Bell, Naeimeh Atabaki-Pasdar, Katherine S. Ruth, E. Louise Thomas, Paul W. Franks
المصدر: Ji, Y, Yiorkas, A M, Frau, F, Mook-kanamori, D, Staiger, H, Thomas, E L, Atabaki-pasdar, N, Campbell, A, Tyrrell, J, Jones, S E, Beaumont, R N, Wood, A R, Tuke, M A, Ruth, K S, Mahajan, A, Murray, A, Freathy, R M, Weedon, M N, Hattersley, A T, Hayward, C, Machann, J, Häring, H, Franks, P, De Mutsert, R, Pearson, E, Stefan, N, Frayling, T M, Allebrandt, K V, Bell, J D, Blakemore, A I & Yaghootkar, H 2018, ' Genome-Wide and Abdominal MRI-Imaging Data Provides Evidence that a Genetically Determined Favourable Adiposity Phenotype is Characterized by Lower Ectopic Liver Fat and Lower Risk of Type 2 Diabetes, Heart Disease and Hypertension ', Diabetes, pp. db180708 . https://doi.org/10.2337/db18-0708
Diabetes, 68(1), 207-219
Diabetes 68, 207-219 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, Endocrinology, Diabetes and Metabolism, LOCI, Adipose tissue, Type 2 diabetes, Body fat percentage, 0302 clinical medicine, 11 Medical and Health Sciences, Adiposity, INSULIN-RESISTANCE, ASSOCIATION, Middle Aged, Magnetic Resonance Imaging, Hypertension, Female, Life Sciences & Biomedicine, Adult, medicine.medical_specialty, Intra-Abdominal Fat, Heart Diseases, METABOLICALLY-OBESE, 030209 endocrinology & metabolism, Endocrinology & Metabolism, 03 medical and health sciences, Insulin resistance, BETA-CELL FUNCTION, Internal medicine, GLYCEMIC TRAITS, Internal Medicine, medicine, Humans, Obesity, METAANALYSIS, NORMAL-WEIGHT, Aged, Science & Technology, IDENTIFICATION, business.industry, Waist-Hip Ratio, medicine.disease, BODY-MASS INDEX, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 2, Metabolic syndrome, business, Body mass index, Genome-Wide Association Study
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be59e4aad6752ff15c4ada85e41ded8
https://pubmed.ncbi.nlm.nih.gov/30352878 -
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المؤلفون: Peter Easton, Joanne Boldison, Stephanie J. Hanna, Lai Khai Siew, James A. Pearson, Adrian Tsui, Li Wen, Terri C. Thayer, Sartaj Ahmed, F. Susan Wong, Evy De Leenheer, Joanne Davies
المصدر: Diabetes. 65(11)
مصطلحات موضوعية: 0301 basic medicine, Male, Adoptive cell transfer, Endocrinology, Diabetes and Metabolism, Mice, Transgenic, Biology, CD8-Positive T-Lymphocytes, 03 medical and health sciences, Epitopes, Mice, 0302 clinical medicine, Mice, Inbred NOD, Internal Medicine, Lymph node stromal cell, Cytotoxic T cell, Animals, Insulin, Proinsulin, NOD mice, Cell Proliferation, Mice, Knockout, Peripheral tolerance, Flow Cytometry, R1, Tolerance induction, CTL, 030104 developmental biology, Diabetes Mellitus, Type 1, 030220 oncology & carcinogenesis, Immunology, Cancer research, Female
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8422e6a2efec236558049c58081aaf66
https://pubmed.ncbi.nlm.nih.gov/27495224 -
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المؤلفون: Julie A. Mangada, Aldo A. Rossini, Todd Pearson, Laurence B. Peterson, Michael A. Brehm, Dale L. Greiner, David V. Serreze, Linda S. Wicker, Leonard D. Shultz
المصدر: Diabetes
مصطلحات موضوعية: Cytotoxicity, Immunologic, Endocrinology, Diabetes and Metabolism, CD40 Ligand, Islets of Langerhans Transplantation, Nod, Biology, medicine.disease_cause, Autoimmunity, Islets of Langerhans, Mice, Mice, Congenic, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Internal Medicine, medicine, Animals, Transplantation, Homologous, 030304 developmental biology, NOD mice, Mice, Inbred C3H, 0303 health sciences, geography, geography.geographical_feature_category, Graft Survival, Antibodies, Monoclonal, Interleukin, Flow Cytometry, Islet, 3. Good health, Killer Cells, Natural, Transplantation, Tolerance induction, Diabetes Mellitus, Type 1, Immunology, Immunology and Transplantation, CD8, 030215 immunology
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المؤلفون: Graham P. Leese, Andrew D. Morris, Mark I. McCarthy, Andrew T. Hattersley, Alex S. F. Doney, Colin N. A. Palmer, Charlotte H. Kimber, Louise A. Donnelly, Peter T. Donnan, Kaixin Zhou, Ewan R. Pearson
المصدر: Diabetes
Zhou, K, Donnelly, L A, Kimber, C H, Donnan, P T, Doney, A S F, Leese, G, Hattersley, A T, McCarthy, M I, Morris, A D, Palmer, C N A & Pearson, E R 2009, ' Reduced-function SLC22A1 polymorphisms encoding organic cation transporter 1 and glycemic response to metformin : A GoDARTS study ', Diabetes, vol. 58, no. 6, pp. 1434-1439 . https://doi.org/10.2337/db08-0896مصطلحات موضوعية: Research design, Drug, Blood Glucose, Male, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, Renal function, 030209 endocrinology & metabolism, Type 2 diabetes, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Genetics, Humans, Hypoglycemic Agents, Treatment Failure, 030304 developmental biology, Glycemic, media_common, Sequence Deletion, Glycated Hemoglobin, 0303 health sciences, Organic cation transport proteins, Polymorphism, Genetic, biology, Dose-Response Relationship, Drug, business.industry, nutritional and metabolic diseases, Genetic Variation, Middle Aged, medicine.disease, Metformin, 3. Good health, Endocrinology, Amino Acid Substitution, Diabetes Mellitus, Type 2, biology.protein, Regression Analysis, Female, business, medicine.drug, Octamer Transcription Factor-1
وصف الملف: application/pdf