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المؤلفون: Rebecca L. Beavil, Kamila J. Pacholarz, Charlotte E. Mills, Perdita E. Barran, Nicholas H. F. Fine, Sally D. Poppitt, Anne Thea McGill, Pratik Choudhary, Guo Cai Huang, J. Kennedy Cruickshank, Sophie R. Sayers, Marta P. Silvestre, Paul W. Caton, Gareth G. Lavery, David J. Hodson, Sam Butterworth
المصدر: Diabetologia
Sayers, S R, Beavil, R L, Fine, N H F, Huang, G C, Choudhary, P, Pacholarz, K J, Barran, P E, Butterworth, S, Mills, C E, Cruickshank, J K, Silvestre, M P, Poppitt, S D, McGill, A T, Lavery, G G, Hodson, D J & Caton, P W 2020, ' Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes ', Diabetologia, vol. 63, no. 2, pp. 313-323 . https://doi.org/10.1007/s00125-019-05029-y
Sayers, S R, Beavil, R L, Fine, N H F, Huang, G C, Choudhary, P, Pacholarz, K J, Barran, P E, Butterworth, S, Mills, C E, Cruickshank, J K, Silvestre, M P, Poppitt, S D, McGill, A-T, Lavery, G G, Hodson, D J & Caton, P W 2020, ' Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes ', Diabetologia, vol. 63, no. 2, pp. 313-323 . https://doi.org/10.1007/s00125-019-05029-yمصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Immunoblotting, Nicotinamide phosphoribosyltransferase, 030209 endocrinology & metabolism, Type 2 diabetes, Alpha cell, Calcium in biology, Mass Spectrometry, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, Structure-Activity Relationship, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Animals, Humans, eNAMPT, Nicotinamide Phosphoribosyltransferase, Cells, Cultured, Inflammation, Chemistry, Reverse Transcriptase Polymerase Chain Reaction, Pancreatic islets, Insulin, Insulin secretion, Extracellularnicotinamide phosphoribosyltransferase, medicine.disease, Glucagon, NAD, 3. Good health, Beta cell, 030104 developmental biology, Endocrinology, medicine.anatomical_structure, Diabetes Mellitus, Type 2, Cytokines, Somatostatin
وصف الملف: application/pdf
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المؤلفون: N. Scholz, Martin Busch, R. G. Bretzel, Dietrich Grönemeyer, T. Linn, B. Santosa, S. Aygen
المصدر: Diabetologia. 43:1257-1265
مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, High-protein diet, Biology, Carbohydrate metabolism, medicine.disease_cause, Glucagon, chemistry.chemical_compound, Surveys and Questionnaires, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Humans, Insulin, Pancreas, Pancreatic hormone, Glucose tolerance test, Glycogen, medicine.diagnostic_test, Gluconeogenesis, Calorimetry, Indirect, Glucose Tolerance Test, Glucose clamp technique, Deuterium, Glucose, Endocrinology, Liver, chemistry, Glucose Clamp Technique, Female, Dietary Proteins, Energy Intake, Oxidation-Reduction
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المؤلفون: Helena Elding Larsson, Bo Ahrén
المصدر: Diabetologia. 43:194-202
مصطلحات موضوعية: medicine.medical_specialty, Time Factors, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Arginine, Glucagon, White People, Cohort Studies, Impaired glucose tolerance, chemistry.chemical_compound, Predictive Value of Tests, Internal medicine, Glucose Intolerance, Insulin Secretion, Internal Medicine, Humans, Insulin, Medicine, Prospective Studies, Pancreatic hormone, Sweden, Analysis of Variance, geography, Glucose tolerance test, geography.geographical_feature_category, medicine.diagnostic_test, business.industry, Glucagon secretion, Glucose Tolerance Test, Middle Aged, Islet, medicine.disease, Postmenopause, Endocrinology, L-Glucose, chemistry, Body Constitution, Regression Analysis, Female, business, Follow-Up Studies
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المؤلفون: Bo Ahrén, Helena Elding Larsson
المصدر: Diabetologia. 42:936-943
مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Arginine, Glucagon, Dexamethasone, Islets of Langerhans, chemistry.chemical_compound, Insulin resistance, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Humans, Insulin, Infusions, Intravenous, Glucocorticoids, Pancreatic hormone, Glycated Hemoglobin, Glucose tolerance test, medicine.diagnostic_test, Chemistry, Glucagon secretion, Fasting, Glucose Tolerance Test, Middle Aged, Glucose clamp technique, medicine.disease, Postmenopause, Endocrinology, L-Glucose, Glucose Clamp Technique, Female, Insulin Resistance
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المؤلفون: Yasser Abdel-Wahab, Peter R. Flatt, Finbarr O'Harte, JM Conlon
المصدر: Diabetologia. 41:1187-1193
مصطلحات موضوعية: medicine.medical_specialty, Glycosylation, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Molecular Sequence Data, Glucagon-Like Peptides, Radioimmunoassay, Peptide, Biology, Glucagon, Cell Line, Islets of Langerhans, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Antibody Specificity, Glucagon-Like Peptide 1, Glycation, Internal medicine, Insulin Secretion, Intestine, Small, Internal Medicine, medicine, Animals, Insulin, Amino Acid Sequence, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Edman degradation, Biological activity, Glucagon-like peptide-1, Peptide Fragments, Rats, Endocrinology, Biochemistry, L-Glucose, chemistry, Sequence Analysis
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المؤلفون: Emmanuel Disse, Andrea Mari, Fabrice Bonnet, Maurice Laville, Kurt Højlund, Christian Anderwald, Pier Marco Piatti, B. Balkau
المساهمون: Foie, métabolismes et cancer, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), EU [QLG1-CT-2001-01252], AstraZeneca (Sweden), Merck Serono, France, Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Diabetologia (Berl.) 55 (2012): 3228–3237. doi:10.1007/s00125-012-2701-3
info:cnr-pdr/source/autori:Bonnet, F.;Disse, E.;Laville, M.;Mari, A.;Hojlund, K.;Anderwald, C.H.;Piatti, P.;Balkau, B./titolo:Moderate alcohol consumption is associated with improved insulin sensitivity, reduced basal insulin secretion rate and lower fasting glucagon concentration in healthy women/doi:10.1007%2Fs00125-012-2701-3/rivista:Diabetologia (Berl.)/anno:2012/pagina_da:3228/pagina_a:3237/intervallo_pagine:3228–3237/volume:55
Diabetologia
Diabetologia, Springer Verlag, 2012, 55 (12), pp.3228-37. ⟨10.1007/s00125-012-2701-3⟩
Bonnet, F, Disse, E, Laville, M, Mari, A, Hojlund, K, Anderwald, C H, Piatti, P, Balkau, B & RISC Study Group 2012, ' Moderate alcohol consumption is associated with improved insulin sensitivity, reduced basal insulin secretion rate and lower fasting glucagon concentration in healthy women ', Diabetologia, vol. 55, no. 12, pp. 3228-37 . https://doi.org/10.1007/s00125-012-2701-3
Diabetologia, 2012, 55 (12), pp.3228-37. ⟨10.1007/s00125-012-2701-3⟩مصطلحات موضوعية: Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Alcohol, Blood Pressure, Type 2 diabetes, Insulin clearance, MESH: Glucose Clamp Technique, chemistry.chemical_compound, 0302 clinical medicine, Surveys and Questionnaires, Insulin, 030212 general & internal medicine, Glucose tolerance test, MESH: Middle Aged, medicine.diagnostic_test, Insulin secretion, MESH: Glucagon, MESH: Blood Pressure, Fasting, Glucose clamp technique, Middle Aged, 3. Good health, MESH: Insulin Resistance, Female, Alcohol consumption, Adult, medicine.medical_specialty, Alcohol Drinking, MESH: Glucose Tolerance Test, MESH: Fasting, 030209 endocrinology & metabolism, MESH: Insulin, Glucagon, 03 medical and health sciences, Insulin resistance, Internal medicine, Internal Medicine, medicine, Humans, MESH: Humans, business.industry, MESH: Questionnaires, MESH: Adult, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology, Glucose Tolerance Test, medicine.disease, Endocrinology, chemistry, Glucose Clamp Technique, Women's Health, Insulin Resistance, business, MESH: Women's Health, MESH: Female, MESH: Alcohol Drinking
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المؤلفون: E. Xu, Christopher J. Rhodes, Lixin Li, Victor Wong, Q Wang, Patricia L. Brubaker
المصدر: Diabetologia. 47(3)
مصطلحات موضوعية: medicine.medical_specialty, Programmed cell death, Endocrinology, Diabetes and Metabolism, Apoptosis, Biology, Protein Serine-Threonine Kinases, Cell Line, Wortmannin, chemistry.chemical_compound, Islets of Langerhans, Glucagon-Like Peptide 1, Internal medicine, Proto-Oncogene Proteins, Insulin Secretion, Internal Medicine, medicine, Staurosporine, Animals, Insulin, Protein Precursors, Protein kinase A, Protein kinase B, Cell growth, Kinase, Reverse Transcriptase Polymerase Chain Reaction, Glucagon, Molecular biology, Peptide Fragments, Endocrinology, chemistry, PRKCB1, Proto-Oncogene Proteins c-akt, Cell Division, medicine.drug
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المؤلفون: David M. Smith, David G.A. Morgan, Rohit N. Kulkarni, RM Wang, Z.L. Wang, Mohammad A. Ghatei, Stephen R. Bloom, James D. Hurley, Allan E. Karlsen
المصدر: Diabetologia. 41(12)
مصطلحات موضوعية: medicine.medical_specialty, Swine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Pertussis toxin, Adenylyl cyclase, Iodine Radioisotopes, chemistry.chemical_compound, Glucagon-Like Peptide 1, Insulin receptor substrate, Internal medicine, mental disorders, Insulin Secretion, Internal Medicine, medicine, Cyclic AMP, Tumor Cells, Cultured, Animals, Insulin, Neuropeptide Y, Peptide YY, Protein Precursors, Receptor, BIBP-3226, Isoproterenol, Neuropeptide Y receptor, Blotting, Northern, Glucagon, humanities, Peptide Fragments, Rats, Receptors, Neuropeptide Y, Pancreatic Neoplasms, Endocrinology, Glucose, chemistry, Adenylyl Cyclase Inhibitors, Insulinoma, Adenylyl Cyclases
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المؤلفون: Helena Elding Larsson, Bo Ahrén
المصدر: Diabetologia. 41(7)
مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, Arginine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Biology, Glucagon, Body Mass Index, chemistry.chemical_compound, Islets of Langerhans, Internal medicine, Insulin Secretion, Internal Medicine, medicine, Humans, Insulin, Pancreatic hormone, Glycated Hemoglobin, geography, geography.geographical_feature_category, Glucagon secretion, Reproducibility of Results, Fasting, Glucose clamp technique, Middle Aged, Islet, Endocrinology, Glucose, L-Glucose, chemistry, Glucose Clamp Technique, Female
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المؤلفون: Helena Elding Larsson, Bo Ahrén
المصدر: Diabetologia. 39(9)
مصطلحات موضوعية: Blood Glucose, medicine.medical_specialty, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Normal Distribution, Arginine, Body Mass Index, Impaired glucose tolerance, chemistry.chemical_compound, Random Allocation, Internal medicine, Glucose Intolerance, Insulin Secretion, Internal Medicine, medicine, Humans, Insulin, Pancreatic hormone, Glucose tolerance test, geography, geography.geographical_feature_category, medicine.diagnostic_test, business.industry, Glucagon secretion, nutritional and metabolic diseases, Glucose clamp technique, Glucose Tolerance Test, Middle Aged, Islet, medicine.disease, Glucagon, Endocrinology, L-Glucose, chemistry, Glucose Clamp Technique, Female, business, hormones, hormone substitutes, and hormone antagonists
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