المؤلفون: D. Volanschi, G. Foletti

المصدر: European Neurology. 34:87-89

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Alpha (ethology), Electroencephalography, Lamotrigine, Audiology, Central nervous system disease, Humans, Medicine, Evoked Potentials, Computerized eeg, Cerebral Cortex, Epilepsy, medicine.diagnostic_test, Triazines, business.industry, Signal Processing, Computer-Assisted, Dominant frequency, Middle Aged, medicine.disease, Anticonvulsant, Neurology, Anesthesia, Anticonvulsants, Drug Therapy, Combination, Female, Neurology (clinical), business, Lennox–Gastaut syndrome, medicine.drug

الوصف: In 12 adults with typical Lennox-Gastaut syndrome and partial epilepsies with secondary bilateral synchrony unsatisfactorily controlled by current antiepileptic drugs, the following computerized background EEG parameters were studied before and during beneficial antiepileptic effect of lamotrigine addition: absolute and relative spectral power density; alpha/theta index; dominant frequency of occipital alpha, theta and delta bands. The only significant influence of lamotrigine addition was a moderate decrease of the median and mean absolute delta power (p0.01). We concluded there was a poor influence of therapeutic doses of lamotrigine on the background diffuse slow dysrhythmias characteristic to severe early encephalopathies which engender both severe secondary epilepsies and different degrees of mental handicap.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb2f515d0bcc38fc2876cf08db59913
https://doi.org/10.1159/000119518

المؤلفون: Shang-Yeong Kwan, I-Hui Lee, Ming-Shung Su

المصدر: European neurology. 45(2)

مصطلحات موضوعية: Male, medicine.medical_specialty, Electrodiagnosis, medicine.diagnostic_test, business.industry, Electroencephalography, Neurological disorder, medicine.disease, Epilepsy, Reflex, Central nervous system disease, Eating, Neurology, Convulsion, medicine, Humans, Neurology (clinical), medicine.symptom, business, Psychiatry, Child, Lennox–Gastaut syndrome, Monitoring, Physiologic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b902b11f1678b190e0bb522fc2bf852
https://pubmed.ncbi.nlm.nih.gov/11244278

المؤلفون: Leopold Saltuari, Gerhard Bauer, Franz Aichner

المصدر: European Neurology. 22:344-350

مصطلحات موضوعية: Adult, Pediatrics, medicine.medical_specialty, Adolescent, Electrodiagnosis, Epilepsies, Myoclonic, Late onset, Electroencephalography, Epilepsy, medicine, Humans, Child, Evoked Potentials, Brain Diseases, medicine.diagnostic_test, business.industry, medicine.disease, Epileptic drop attack, Epilepsy, Absence, Neurology, Anesthesia, Brain Damage, Chronic, Epilepsies, Partial, Neurology (clinical), business, Lennox–Gastaut syndrome

الوصف: 26 adult epileptic patients with diffuse slow spikes and waves and start of seizures after the age of 6 years were analyzed. The seizure spectrum encompasses generalized and focal seizures. The occurrence of several types of seizures is the rule. Epileptic drop attacks are most characteristic. Atonic, tonic and myoclonic features may be present in this type of seizure. Neurological and mental deficits are common. Compared with Lennox-Gastaut syndrome of children, the degree of intellectual impairment is relatively mild. As to the etiology a primary and a secondary group can be distinguished. Genetic predisposition seems to play a crucial role in the primary group.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd7e823b54d6104d2fe6c5cfce57304
https://doi.org/10.1159/000115581