المؤلفون: Lee D; Department of Pathology, The University of Hong Kong, Hong Kong., Xu IM; Department of Pathology, The University of Hong Kong, Hong Kong., Chiu DK; Department of Pathology, The University of Hong Kong, Hong Kong., Leibold J; Memorial Sloan Kettering Cancer Center, New York, NY., Tse AP; Department of Pathology, The University of Hong Kong, Hong Kong., Bao MH; Department of Pathology, The University of Hong Kong, Hong Kong., Yuen VW; Department of Pathology, The University of Hong Kong, Hong Kong., Chan CY; Department of Pathology, The University of Hong Kong, Hong Kong., Lai RK; Department of Pathology, The University of Hong Kong, Hong Kong., Chin DW; Department of Pathology, The University of Hong Kong, Hong Kong., Chan DF; Department of Pathology, The University of Hong Kong, Hong Kong., Cheung TT; Department of Surgery, The University of Hong Kong, Hong Kong.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong., Chok SH; Department of Surgery, The University of Hong Kong, Hong Kong.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong., Wong CM; Department of Pathology, The University of Hong Kong, Hong Kong.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong., Lowe SW; Memorial Sloan Kettering Cancer Center, New York, NY., Ng IO; Department of Pathology, The University of Hong Kong, Hong Kong.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong., Wong CC; Department of Pathology, The University of Hong Kong, Hong Kong.; State Key Laboratory for Liver Research, The University of Hong Kong, Hong Kong.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2019 Apr; Vol. 69 (4), pp. 1768-1786. Date of Electronic Publication: 2019 Mar 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Auranofin/*therapeutic use , Carcinoma, Hepatocellular/*metabolism , Liver Neoplasms/*metabolism , Oxidative Stress/*drug effects , Thioredoxin Reductase 1/*metabolism, Animals ; Antineoplastic Agents/therapeutic use ; Auranofin/pharmacology ; Carcinoma, Hepatocellular/drug therapy ; Drug Screening Assays, Antitumor ; Hep G2 Cells ; Humans ; Kelch-Like ECH-Associated Protein 1/metabolism ; Liver Neoplasms/drug therapy ; Mice ; NF-E2-Related Factor 2/metabolism ; Sorafenib/therapeutic use ; Thioredoxin Reductase 1/antagonists & inhibitors