المؤلفون: Ng WH; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore 168583, Singapore., Soo KC; Division of Surgery and Surgical Oncology, National Cancer Centre Singapore, Singapore 168583, Singapore., Huynh H; Laboratory of Molecular Endocrinology, National Cancer Centre Singapore, Singapore 168583, Singapore.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 26; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use, Humans ; Animals ; Mice ; Sorafenib/pharmacology ; Sorafenib/therapeutic use ; Vinorelbine/pharmacology ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis ; Cell Line, Tumor ; Cell Proliferation ; Xenograft Model Antitumor Assays

المؤلفون: Rodríguez-Medina C; Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, 35019 Las Palmas de Gran Canaria, Spain., Stuckey R; Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, 35019 Las Palmas de Gran Canaria, Spain., Bilbao-Sieyro C; Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, 35019 Las Palmas de Gran Canaria, Spain.; Morphology Department, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain., Gómez-Casares MT; Hematology Department, Hospital Universitario de Gran Canaria Dr. Negrín, 35019 Las Palmas de Gran Canaria, Spain.; Department of Medical Sciences, Universidad de Las Palmas de Gran Canaria, 35016 Las Palmas de Gran Canaria, Spain.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 24; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Myeloid, Acute*/drug therapy , Leukemia, Myeloid, Acute*/genetics , Leukemia, Myeloid, Acute*/pathology , Antineoplastic Agents*/therapeutic use , Sulfonamides*, Adult ; Humans ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Biomarkers

المؤلفون: Leśniak M; Student Scientific Society of Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-093 Lublin, Poland., Lipniarska J; Student Scientific Society of Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-093 Lublin, Poland., Majka P; Student Scientific Society of Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-093 Lublin, Poland., Lejman M; Independent Laboratory of Genetic Diagnostics, Medical University of Lublin, 20-093 Lublin, Poland., Zawitkowska J; Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, 20-093 Lublin, Poland.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 24; Vol. 24 (23). Date of Electronic Publication: 2023 Nov 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/therapeutic use , Leukemia, Myeloid, Acute*/pathology , Hematologic Neoplasms*/drug therapy , Hematologic Neoplasms*/etiology, Adult ; Humans ; Child ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Proto-Oncogene Proteins c-bcl-2

المؤلفون: Rizzuto A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Pirrera A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Gigliotta E; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Mancuso S; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Vullo C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Camarda GM; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Rotolo C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Roppolo A; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Spoto C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Gentile M; Hematology Unit, 'Annunziata' Hospital of Cosenza, 87100 Cosenza, Italy.; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy., Botta C; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy., Siragusa S; Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (ProMISE), University of Palermo, 90141 Palermo, Italy.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 09; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 09.

نوع المنشور: Systematic Review; Meta-Analysis; Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/genetics , Antineoplastic Agents*/therapeutic use, Humans ; Network Meta-Analysis ; Randomized Controlled Trials as Topic ; Antibodies, Monoclonal/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Biology

المؤلفون: Fuentealba-Manosalva O; Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5110566, Chile., Mansilla M; Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5110566, Chile., Buelvas N; Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5110566, Chile., Martin-Martin A; Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5110566, Chile., Torres CG; Departamento de Ciencias Clínicas, Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile.; Laboratorio Centralizado de Investigación Veterinaria (LaCIV), Facultad de Ciencias Veterinarias y Pecuarias, Universidad de Chile, Santiago 8820808, Chile., López-Muñoz RA; Instituto de Farmacología y Morfofisiología, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Valdivia 5110566, Chile.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 03; Vol. 24 (11). Date of Electronic Publication: 2023 Jun 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology, Animals ; Dogs ; Celecoxib/pharmacology ; Drug Therapy, Combination ; Software ; Drug Combinations ; Drug Synergism ; Antineoplastic Combined Chemotherapy Protocols/pharmacology

المؤلفون: Hines JB; Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA., Bowar B; Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA., Levine E; Booth School of Business, University of Chicago, Chicago, IL 60637, USA., Esposito A; Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA., Garassino MC; Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA., Bestvina CM; Department of Medicine, Section of Hematology/Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 May 29; Vol. 24 (11). Date of Electronic Publication: 2023 May 29.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/etiology , Lung Neoplasms*/etiology , Antineoplastic Agents*/adverse effects, United States ; Humans ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use

المؤلفون: Kotmayer L; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., László T; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Mikala G; South-Pest Central Hospital, National Institute of Hematology and Infectology, 1097 Budapest, Hungary., Kiss R; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Lévay L; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Hegyi LL; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Gróf S; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Nagy T; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary., Barna G; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Farkas P; Department of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary., Weisinger J; Department of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary., Nagy Z; Department of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary., Balogh A; Department of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary., Masszi T; Department of Internal Medicine and Hematology, Semmelweis University, 1085 Budapest, Hungary., Demeter J; Department of Internal Medicine and Oncology, Semmelweis University, 1085 Budapest, Hungary., Sulák A; 2nd Department of Internal Medicine and Cardiology Center, University of Szeged, 6725 Szeged, Hungary., Kohl Z; 1st Department of Internal Medicine, Clinical Centre, University of Pécs, 7622 Pécs, Hungary., Alizadeh H; 1st Department of Internal Medicine, Clinical Centre, University of Pécs, 7622 Pécs, Hungary., Egyed M; Kaposi Mór University Teaching Hospital of County Somogy, 7400 Kaposvár, Hungary., Pettendi P; Hetényi Géza Hospital, Clinic of County Jász-Nagykun-Szolnok, 5000 Szolnok, Hungary., Gergely L; Division of Hematology, Department of Internal Medicine, University of Debrecen, 4032 Debrecen, Hungary., Plander M; Markusovszky University Teaching Hospital, 9700 Szombathely, Hungary., Pauker Z; Borsod-Abaúj-Zemplén County Hospital and University Teaching Hospital, 3515 Miskolc, Hungary., Masszi A; National Institute of Oncology, 1122 Budapest, Hungary., Matolcsy A; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.; Department of Laboratory Medicine, Karolinska Institute, 171 77 Solna, Sweden., Szász R; Division of Hematology, Department of Internal Medicine, University of Debrecen, 4032 Debrecen, Hungary., Bödör C; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary., Alpár D; HCEMM-SE Molecular Oncohematology Research Group, Department of Pathology and Experimental Cancer Research, Semmelweis University, 1085 Budapest, Hungary.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 18; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Leukemia, Lymphocytic, Chronic, B-Cell*/drug therapy , Leukemia, Lymphocytic, Chronic, B-Cell*/genetics , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/therapeutic use, Humans ; Drug Resistance, Neoplasm/genetics ; Recurrence ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Bridged Bicyclo Compounds, Heterocyclic/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Mutation ; Proto-Oncogene Proteins c-bcl-2/genetics ; Disease Progression

المؤلفون: Smolobochkin A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Niyazova D; Laboratory of Engineering Profile, Department of Engineering Technology, Korkyt Ata Kyzylorda University, Ayteke bi Str., 29A, Kyzylorda 120014, Kazakhstan., Gazizov A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Syzdykbayev M; Laboratory of Engineering Profile, Department of Engineering Technology, Korkyt Ata Kyzylorda University, Ayteke bi Str., 29A, Kyzylorda 120014, Kazakhstan.; Nazarbayev Intellectual School Chemical-Biological Direction in Kyzylorda, Sultan Beybars Str., 6, Kyzylorda 120014, Kazakhstan., Voloshina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Amerhanova S; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Lyubina A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Neganova M; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia.; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Severnij pr., 1, Chernogolovka 142432, Russia., Aleksandrova Y; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia.; Institute of Physiologically Active Compounds at Federal Research Center of Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences, Severnij pr., 1, Chernogolovka 142432, Russia., Babaeva O; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Voronina J; N.S. Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninskii pr., 31, Moscow 119071, Russia., Appazov N; Laboratory of Engineering Profile, Department of Engineering Technology, Korkyt Ata Kyzylorda University, Ayteke bi Str., 29A, Kyzylorda 120014, Kazakhstan.; Limited Liability Partnership «DPS-Kyzylorda», Amangeldi Str., 112A, Kyzylorda 120014, Kazakhstan., Sinyashin O; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Alabugin I; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia.; Department of Chemistry and Biochemistry, Florida State University, Chieftan Way Str., 95, Tallahassee, FL 32306-3290, USA., Burilov A; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia., Pudovik M; Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov Str., 8, Kazan 420088, Russia.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 18; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Apoptosis*/drug effects, Humans ; Cell Line, Tumor ; Methane/analogs & derivatives ; Methane/chemistry ; Methane/pharmacology ; Cell Proliferation/drug effects ; Xanthenes/pharmacology ; Xanthenes/chemistry

المؤلفون: Powała A; Department of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, 1 Stefana Banacha, 02-097 Warsaw, Poland., Żołek T; Department of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, 1 Stefana Banacha, 02-097 Warsaw, Poland., Brown G; School of Biomedical Sciences, Institute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK., Kutner A; Department of Drug Chemistry Pharmaceutical and Biomedical Analysis, Faculty of Pharmacy, Medical University of Warsaw, 1 Stefana Banacha, 02-097 Warsaw, Poland.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 16; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, Calcitriol*/metabolism , Receptors, Calcitriol*/agonists , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry, Humans ; Animals ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Calcitriol/pharmacology ; Calcitriol/analogs & derivatives ; Calcitriol/chemistry ; Structure-Activity Relationship ; Vitamin D/analogs & derivatives ; Vitamin D/pharmacology ; Vitamin D/chemistry

المؤلفون: Tagari EV; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Sifnaiou E; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Tsolis T; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece., Garoufis A; Laboratory of Inorganic Chemistry, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.; Institute of Materials Science and Computing, University Research Centre of Ioannina (URCI), 45110 Ioannina, Greece.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 13; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , DNA*/chemistry , DNA*/metabolism, Humans ; Ligands ; Organoplatinum Compounds/pharmacology ; Organoplatinum Compounds/chemistry ; Organoplatinum Compounds/chemical synthesis ; Cell Line, Tumor ; Hydrolysis ; Platinum/chemistry ; Platinum/pharmacology ; A549 Cells