المؤلفون: Lashen A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Nottingham University Hospital, City Campus, Nottingham NG5 1PB, UK., Alqahtani S; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Shoqafi A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Algethami M; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Jeyapalan JN; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Faculty of Medicine and Health Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK., Mongan NP; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Faculty of Medicine and Health Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA., Rakha EA; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Nottingham University Hospital, City Campus, Nottingham NG5 1PB, UK., Madhusudan S; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Oncology, Nottingham University Hospitals, Nottingham NG5 1PB, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 May 06; Vol. 25 (9). Date of Electronic Publication: 2024 May 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Cyclin-Dependent Kinase 2*/metabolism , Cyclin-Dependent Kinase 2*/genetics , Breast Neoplasms*/pathology , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Breast Neoplasms*/mortality , Carcinoma, Intraductal, Noninfiltrating*/pathology , Carcinoma, Intraductal, Noninfiltrating*/genetics , Carcinoma, Intraductal, Noninfiltrating*/metabolism, Humans ; Female ; Prognosis ; Middle Aged ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Neoplasm Staging ; Carcinoma, Ductal, Breast/pathology ; Carcinoma, Ductal, Breast/metabolism ; Carcinoma, Ductal, Breast/genetics ; Carcinoma, Ductal, Breast/mortality ; Aged ; Gene Expression Regulation, Neoplastic ; Neoplasm Invasiveness ; Tumor Suppressor Protein p53/metabolism ; Tumor Suppressor Protein p53/genetics

المؤلفون: Lashen A; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Nottingham University Hospital, City Campus, Nottingham NG5 1PB, UK., Algethami M; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Alqahtani S; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Shoqafi A; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Sheha A; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Jeyapalan JN; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Faculty of Medicine and Health Sciences, Centre for Cancer Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK., Mongan NP; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Faculty of Medicine and Health Sciences, Centre for Cancer Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK.; Department of Pharmacology, Weill Cornell Medicine, New York, NY 10065, USA., Rakha EA; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Madhusudan S; Naaz Coker Ovarian Cancer Research Centre, Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Oncology, Nottingham University Hospitals, Nottingham NG5 1PB, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 05; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Retinoblastoma* , Ovarian Neoplasms*/genetics , Retinal Neoplasms*, Female ; Humans ; Carcinoma, Ovarian Epithelial ; Cyclin D1/genetics ; Cyclin-Dependent Kinase 2/genetics ; Ubiquitin-Protein Ligases ; Retinoblastoma Binding Proteins/genetics

المؤلفون: Kurozumi S; Department of Breast Surgery, International University of Health and Welfare, Chiba 286-8520, Japan.; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Seki N; Department of Functional Genomics, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan., Narusawa E; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Honda C; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Tokuda S; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Nakazawa Y; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Yokobori T; Initiative for Advanced Research, Gunma University, Gunma 371-8511, Japan., Katayama A; Department of Diagnostic Pathology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Mongan NP; Biodiscovery Institute, Faculty of Medicine and Health Sciences, University of Nottingham, Nottingham NG7 2RD, UK., Rakha EA; Academic Unit for Translational Medical Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK.; Pathology Department, Hamad Medical Corporation, Doha P.O. Box 3050, Qatar., Oyama T; Department of Diagnostic Pathology, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Fujii T; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Shirabe K; Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma 371-8511, Japan., Horiguchi J; Department of Breast Surgery, International University of Health and Welfare, Chiba 286-8520, Japan.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 19; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , Breast Neoplasms*/genetics, Humans ; Female ; Breast ; Cluster Analysis ; Computational Biology

المؤلفون: Alblihy A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Ali R; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Algethami M; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Ritchie AA; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Shoqafi A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Alqahtani S; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Mesquita KA; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Toss MS; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Ordóñez-Morán P; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Jeyapalan JN; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK.; Faculty of Medicine and Health Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington LE12 5RD, UK., Dekker L; Nottingham Biodiscovery Institute, School of Pharmacy, University of Nottingham, Nottingham NG7 3RD, UK., Salerno M; North West Cancer Research Institute, School of Medical and Health Sciences, Bangor University, Bangor LL57 2UW, UK., Hartsuiker E; North West Cancer Research Institute, School of Medical and Health Sciences, Bangor University, Bangor LL57 2UW, UK., Grabowska AM; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Rakha EA; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK.; Department of Pathology, Nottingham University Hospitals, City Campus, Nottingham NG5 1PB, UK., Mongan NP; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK., Madhusudan S; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham NG7 3RD, UK.; Department of Oncology, Nottingham University Hospitals, Nottingham NG5 1PB, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 30; Vol. 24 (13). Date of Electronic Publication: 2023 Jun 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins*/metabolism , Ovarian Neoplasms*/drug therapy , Ovarian Neoplasms*/genetics, Humans ; Female ; MRE11 Homologue Protein/genetics ; MRE11 Homologue Protein/metabolism ; HeLa Cells ; Precision Medicine ; BRCA2 Protein/metabolism ; DNA Repair ; Cell Line, Tumor

المؤلفون: Xu Q; Department of Oncology, Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA., Kaur J; Department of Biology, Georgia State University, Atlanta, GA 30303, USA., Wylie D; Center for Biomedical Research Support, The University of Texas at Austin, Austin, TX 78705, USA., Mittal K; Department of Biology, Georgia State University, Atlanta, GA 30303, USA., Li H; Department of Mathematics and Statistics, Georgia State University, Atlanta, GA 30303, USA., Kolachina R; Department of Biology, Georgia State University, Atlanta, GA 30303, USA., Aleskandarany M; University of Nottingham and Nottingham University Hospitals, Nottingham NG7 2UH, UK., Toss MS; University of Nottingham and Nottingham University Hospitals, Nottingham NG7 2UH, UK., Green AR; University of Nottingham and Nottingham University Hospitals, Nottingham NG7 2UH, UK., Yang J; Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78705, USA.; Departments of Diagnostic Medicine, Biomedical Engineering, and Oncology, The University of Texas at Austin, Austin, TX 78705, USA., Yankeelov TE; Department of Oncology, Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA.; Oden Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78705, USA.; Departments of Diagnostic Medicine, Biomedical Engineering, and Oncology, The University of Texas at Austin, Austin, TX 78705, USA., Bhattarai S; Department of Biology, Georgia State University, Atlanta, GA 30303, USA., Janssen EAM; Department of Pathology, Stavanger University Hospital, 4011 Stavanger, Norway., Kong J; Department of Mathematics and Statistics, Georgia State University, Atlanta, GA 30303, USA., Rakha EA; University of Nottingham and Nottingham University Hospitals, Nottingham NG7 2UH, UK., Kowalski J; Department of Oncology, Livestrong Cancer Institutes, The University of Texas at Austin, Austin, TX 78712, USA., Aneja R; Department of Biology, Georgia State University, Atlanta, GA 30303, USA.; Department of Clinical and Diagnostic Sciences, School of Health Professions, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2022 Nov 01; Vol. 23 (21). Date of Electronic Publication: 2022 Nov 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Triple Negative Breast Neoplasms*/pathology, Humans ; Bayes Theorem ; Neoplasm Recurrence, Local/genetics ; Neoplasm Recurrence, Local/pathology ; Lymphocytes, Tumor-Infiltrating ; Lymph Nodes/pathology ; Biomarkers, Tumor/metabolism

المؤلفون: Alfarsi LH; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK., El-Ansari R; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK., Craze ML; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK., Masisi BK; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK., Mohammed OJ; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK., Ellis IO; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.; Cellular Pathology, Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK., Rakha EA; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.; Cellular Pathology, Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Road, Nottingham NG5 1PB, UK., Green AR; Nottingham Breast Cancer Research Centre, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham Biodiscovery Institute, University Park, Nottingham NG7 2RD, UK.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2020 Feb 19; Vol. 21 (4). Date of Electronic Publication: 2020 Feb 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Hormonal/*therapeutic use , Biomarkers, Tumor/*metabolism , Breast Neoplasms/*metabolism , Fusion Regulatory Protein 1, Heavy Chain/*metabolism , Gene Expression Regulation, Neoplastic/*drug effects , Large Neutral Amino Acid-Transporter 1/*metabolism , Receptors, Estrogen/*metabolism, Biomarkers, Tumor/genetics ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Proliferation/genetics ; Cohort Studies ; Drug Resistance, Neoplasm/genetics ; Female ; Fusion Regulatory Protein 1, Heavy Chain/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Gene Knockdown Techniques ; Humans ; Kaplan-Meier Estimate ; Large Neutral Amino Acid-Transporter 1/genetics ; Middle Aged ; Neoplasm Metastasis/genetics ; Prognosis ; RNA, Small Interfering ; Regression Analysis ; Tamoxifen/pharmacology ; Tamoxifen/therapeutic use