المؤلفون: Zidan A; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire ave., Silver Spring, MD 20903, USA. Electronic address: Ahmed.Zidan@fda.hhs.gov., Kotamarthy L; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire ave., Silver Spring, MD 20903, USA; Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey., Ramachandran R; Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey., Ashraf M; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire ave., Silver Spring, MD 20903, USA., O'Connor T; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, 10903 New Hampshire ave., Silver Spring, MD 20903, USA.

المصدر: International journal of pharmaceutics [Int J Pharm] 2022 Jul 25; Vol. 623, pp. 121964. Date of Electronic Publication: 2022 Jun 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Metoprolol* , Technology, Pharmaceutical*/methods, Delayed-Action Preparations ; Drug Compounding/methods ; Particle Size ; Tablets

المؤلفون: Kotamarthy L; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA; Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, USA., Feng X; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA., Alayoubi A; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA., Kumar Bolla P; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA., Ramachandran R; Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey, USA., Ashraf M; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA., O'Connor T; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA., Zidan A; Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center for Drug Evaluation and Research, U.S. Food and Drug Administration, USA. Electronic address: Ahmed.Zidan@fda.hhs.gov.

المصدر: International journal of pharmaceutics [Int J Pharm] 2022 Apr 05; Vol. 617, pp. 121598. Date of Electronic Publication: 2022 Feb 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Excipients* , Metoprolol*, Drug Compounding ; Particle Size ; Solubility ; Tablets ; Technology, Pharmaceutical

المؤلفون: Monteyne T; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: Tinne.Monteyne@UGent.be., Adriaensens P; Laboratory of Applied and Analytical Chemistry, Institute of Material Science, Hasselt University, Campus Diepenbeek, Agoralaan, Building D, Diepenbeek, Belgium. Electronic address: Peter.Adriaensens@UHasselt.be., Brouckaert D; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: Davinia.Brouckaert@UGent.be., Remon JP; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: JeanPaul.Remon@UGent.be., Vervaet C; Laboratory of Pharmaceutical Technology, Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: Chris.Vervaet@UGent.be., De Beer T; Laboratory of Pharmaceutical Process Analytical Technology, Department of Pharmaceutical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: Thomas.DeBeer@UGent.be.

المصدر: International journal of pharmaceutics [Int J Pharm] 2016 Oct 15; Vol. 512 (1), pp. 158-167. Date of Electronic Publication: 2016 Jul 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Metoprolol/*pharmacokinetics , Polyethylene Glycols/*chemistry , Stearic Acids/*chemistry, Crystallization ; Delayed-Action Preparations/chemistry ; Delayed-Action Preparations/pharmacokinetics ; Drug Compounding/methods ; Drug Liberation ; Drug Stability ; Metoprolol/chemistry

المؤلفون: Vanhoorne V; Laboratory of Pharmaceutical Technology, Ghent University, Belgium., Vanbillemont B; Laboratory of Pharmaceutical Technology, Ghent University, Belgium., Vercruysse J; Laboratory of Pharmaceutical Technology, Ghent University, Belgium., De Leersnyder F; Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium., Gomes P; Laboratory of Nanotechnology, Centro Universitário Franciscano, Brazil., Beer TD; Laboratory of Pharmaceutical Process Analytical Technology, Ghent University, Belgium., Remon JP; Laboratory of Pharmaceutical Technology, Ghent University, Belgium., Vervaet C; Laboratory of Pharmaceutical Technology, Ghent University, Belgium. Electronic address: chris.vervaet@ugent.be.

المصدر: International journal of pharmaceutics [Int J Pharm] 2016 May 30; Vol. 505 (1-2), pp. 61-8. Date of Electronic Publication: 2016 Mar 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Excipients/*chemistry , Hypromellose Derivatives/*chemistry , Metoprolol/*administration & dosage , Technology, Pharmaceutical/*methods, Chemistry, Pharmaceutical/methods ; Delayed-Action Preparations ; Drug Liberation ; Metoprolol/chemistry ; Particle Size ; Solubility ; Starch/chemistry ; Tablets ; Temperature ; Tensile Strength ; Water/chemistry

المؤلفون: Zur M; Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel., Cohen N; Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel., Agbaria R; Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel., Dahan A; Department of Clinical Pharmacology, School of Pharmacy, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel. Electronic address: arikd@bgu.ac.il.

المصدر: International journal of pharmaceutics [Int J Pharm] 2015 Jul 15; Vol. 489 (1-2), pp. 304-10. Date of Electronic Publication: 2015 May 06.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Delayed-Action Preparations/*pharmacokinetics , Glipizide/*pharmacokinetics , Hypoglycemic Agents/*pharmacokinetics , Intestinal Mucosa/*metabolism , Metoprolol/*pharmacokinetics, Animals ; Biopharmaceutics ; Caco-2 Cells ; Delayed-Action Preparations/administration & dosage ; Delayed-Action Preparations/chemistry ; Glipizide/administration & dosage ; Glipizide/chemistry ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/chemistry ; Intestinal Absorption ; Male ; Membranes, Artificial ; Metoprolol/administration & dosage ; Metoprolol/chemistry ; Permeability ; Rats, Wistar ; Solubility

المؤلفون: Li L; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Wang L; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Li J; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Jiang S; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Wang Y; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Zhang X; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Ding J; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Yu T; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China., Mao S; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: maoshirui@syphu.edu.cn.

المصدر: International journal of pharmaceutics [Int J Pharm] 2014 Dec 10; Vol. 476 (1-2), pp. 253-65. Date of Electronic Publication: 2014 Oct 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Chitosan/*chemistry , Metoprolol/*analogs & derivatives , Polymers/*chemistry , Theophylline/*administration & dosage, Anions ; Calorimetry, Differential Scanning ; Chemistry, Pharmaceutical/methods ; Delayed-Action Preparations ; Drug Liberation ; Gastrointestinal Tract/metabolism ; Hydrogen-Ion Concentration ; Metoprolol/administration & dosage ; Metoprolol/chemistry ; Solubility ; Spectroscopy, Fourier Transform Infrared ; Tablets ; Theophylline/chemistry

المؤلفون: Haaser M; School of Pharmacy, University of Otago, Dunedin, New Zealand; Cavendish Laboratories, University of Cambridge, Cambridge, United Kingdom; TeraView Ltd., Cambridge, United Kingdom., Karrout Y, Velghe C, Cuppok Y, Gordon KC, Pepper M, Siepmann J, Rades T, Taday PF, Strachan CJ

المصدر: International journal of pharmaceutics [Int J Pharm] 2013 Dec 05; Vol. 457 (2), pp. 521-6. Date of Electronic Publication: 2013 May 27.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Terahertz Imaging*, Methylcellulose/*analogs & derivatives , Metoprolol/*analogs & derivatives , Technology, Pharmaceutical/*methods, Delayed-Action Preparations/chemistry ; Hypromellose Derivatives ; Methylcellulose/chemistry ; Metoprolol/chemistry ; Microscopy, Electron, Scanning ; Surface Properties

المؤلفون: Van Renterghem J; Laboratory of Pharmaceutical Technology, Ottergemsesteenweg 460, 9000 Ghent, Belgium. Electronic address: jeroen.vanrenterghem@ugent.be., Van de Steene S; Laboratory of Pharmaceutical Process Analytical Technology, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Digkas T; Laboratory of Pharmaceutical Process Analytical Technology, Ottergemsesteenweg 460, 9000 Ghent, Belgium., Richter M; Thermo Fisher Scientific, Dieselstraße 4, 76227 Karlsruhe, Germany., Vervaet C; Laboratory of Pharmaceutical Technology, Ottergemsesteenweg 460, 9000 Ghent, Belgium., De Beer T; Laboratory of Pharmaceutical Process Analytical Technology, Ottergemsesteenweg 460, 9000 Ghent, Belgium.

المصدر: International journal of pharmaceutics [Int J Pharm] 2019 Oct 05; Vol. 569, pp. 118587. Date of Electronic Publication: 2019 Aug 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Delayed-Action Preparations/*chemistry , Technology, Pharmaceutical/*methods, Drug Liberation ; Metoprolol/chemistry ; Polymethacrylic Acids/chemistry

المؤلفون: Lowinger MB; College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA; MRL, Merck & Co, Inc., 126 E. Lincoln Ave, Rahway, NJ 07065, USA. Electronic address: michael.lowinger@utexas.edu., Ormes JD; MRL, Merck & Co, Inc., 126 E. Lincoln Ave, Rahway, NJ 07065, USA., Su Y; MRL, Merck & Co, Inc., 126 E. Lincoln Ave, Rahway, NJ 07065, USA., Small JH; MRL, Merck & Co, Inc., 126 E. Lincoln Ave, Rahway, NJ 07065, USA., Williams RO 3rd; College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA., Zhang F; College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Austin, TX 78712, USA. Electronic address: feng.zhang@austin.utexas.edu.

المصدر: International journal of pharmaceutics [Int J Pharm] 2019 Sep 10; Vol. 568, pp. 118550. Date of Electronic Publication: 2019 Jul 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Membranes, Artificial*, Polyurethanes/*chemistry, Dextrans/chemistry ; Diffusion ; Drug Implants ; Emtricitabine/chemistry ; Fluorescein-5-isothiocyanate/analogs & derivatives ; Fluorescein-5-isothiocyanate/chemistry ; Hydrophobic and Hydrophilic Interactions ; Ibuprofen/chemistry ; Metoprolol/chemistry ; Molecular Weight ; Permeability ; Porosity

المؤلفون: Zhao N; Division of Product Quality Research, Office of Testing and Research, Center for Drug Evaluation and Research (CDER), Food and Drug Administration (FDA), United States., Zidan A, Tawakkul M, Sayeed VA, Khan M

المصدر: International journal of pharmaceutics [Int J Pharm] 2010 Nov 30; Vol. 401 (1-2), pp. 25-31. Date of Electronic Publication: 2010 Sep 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Adrenergic beta-Antagonists/*chemistry , Metoprolol/*analogs & derivatives, Adrenergic beta-Antagonists/standards ; Chemistry, Pharmaceutical ; Delayed-Action Preparations ; Metoprolol/chemistry ; Metoprolol/standards ; Quality Control ; Spectroscopy, Near-Infrared ; Tablets