المؤلفون: Mehwish Nawaz, Haji Muhammad Shoaib Khan, Naveed Akhtar, Wajeeha Arshad

المصدر: Journal of Cosmetic Dermatology. 19:1667-1675

مصطلحات موضوعية: food.ingredient, Erythema, Flavonoid, Placebo-controlled study, Human skin, Dermatology, Melanin, 030207 dermatology & venereal diseases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, food, medicine, Humans, Phenols, Cinnamomum, Skin, chemistry.chemical_classification, integumentary system, Traditional medicine, Plant Extracts, Plant Leaves, Sebum, chemistry, 030220 oncology & carcinogenesis, Female, medicine.symptom, Cosmeceutical, Cinnamomum tamala

الوصف: Background Phenolic and flavonoid compounds found in plants alleviate the photo-damaging skin conditions by playing a major role in skin rejuvenation. Aims The aim of the study was to explore the cosmeceutical effects of Cinnamomum tamala extract. Objective Recent research was aimed to quantify phenols and flavonoids in the natural extract of C tamala leaves, to develop its phyto-cosmetic emulgel and to assess effects of emulgel on healthy human skin. Method Phenols and flavonoids in C tamala (CT) extract were quantified by using ELISA assay. Emulgel formulation loaded with 4% C tamala (CT emulgel) was developed, and its cosmetic effects were evaluated on the cheeks of 13 healthy female test volunteers by comparing with placebo (base). Facial parameters including melanin, erythema, sebum, and visible facial pores (size and area) were studied by using Mexameter® , Sebumeter® , and VisioFace® at regular interval for 90 days. Results Total phenolic content and total flavonoids content of C tamala leaves extract were found to be 73.08 ± 0.0078 mg GAE/g and 52.63 ± 0.0060 mg QE/g CT extract respectively. As compared to placebo (base), CT emulgel was found to be significantly (P ≤ .05) effective in minimizing skin photo-damaging effects by reducing the levels of melanin, erythema, and sebum and size and count of both fine and large facial pores. Conclusion Cinnamomum tamala leaves extract, being a rich source of phenols and flavonoids minimized the photo-damaging effects by reducing skin melanin, erythema, and excess sebum; improving the skin imperfections by reducing facial pore count and area as assessed by advanced imaging and bioengineering techniques.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4eae74c5ac42d589b4597a8f6172c2
https://doi.org/10.1111/jocd.13198

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.