المؤلفون: Kumada H; Department of Hepatology, Toranomon Hospital, Tokyo, Japan. kumahiro@toranomon.gr.jp., Watanabe T; Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan., Suzuki F; Department of Hepatology, Toranomon Hospital, Tokyo, Japan., Ikeda K; Department of Hepatology, Toranomon Hospital, Tokyo, Japan., Sato K; Department of Medicine and Molecular Science, Gunma University Hospital, Maebashi, Japan., Toyoda H; Department of Gastroenterology, Ogaki Municipal Hospital, Gifu, Japan., Atsukawa M; Department of Internal Medicine, Nippon Medical School, Tokyo, Japan., Ido A; Department of Human and Environmental Sciences, Kagoshima University Hospital, Kagoshima, Japan., Takaki A; Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan., Enomoto N; The First Department of Internal Medicine, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan., Kato K; AbbVie Inc., North Chicago, IL, USA., Alves K; AbbVie Inc., North Chicago, IL, USA., Burroughs M; AbbVie Inc., North Chicago, IL, USA., Redman R; AbbVie Inc., North Chicago, IL, USA., Pugatch D; AbbVie Inc., North Chicago, IL, USA., Pilot-Matias TJ; AbbVie Inc., North Chicago, IL, USA., Krishnan P; AbbVie Inc., North Chicago, IL, USA., Oberoi RK; AbbVie Inc., North Chicago, IL, USA., Xie W; AbbVie Inc., North Chicago, IL, USA., Chayama K; Department of Gastroenterology and Metabolism, Institute of Biomedical and Health Sciences, Hiroshima University Hospital, Hiroshima, Japan.

المصدر: Journal of gastroenterology [J Gastroenterol] 2018 Apr; Vol. 53 (4), pp. 566-575. Date of Electronic Publication: 2017 Oct 20.

نوع المنشور: Clinical Trial, Phase III; Journal Article; Multicenter Study

بيانات الدورية: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*therapeutic use , Benzimidazoles/*therapeutic use , Hepacivirus/*genetics , Hepatitis C, Chronic/*drug therapy , Quinoxalines/*therapeutic use , Renal Insufficiency/*complications , Sulfonamides/*therapeutic use, Adolescent ; Adult ; Aged ; Aminoisobutyric Acids ; Antiviral Agents/adverse effects ; Benzimidazoles/adverse effects ; Cyclopropanes ; Drug Therapy, Combination ; Female ; Genotype ; Hepacivirus/isolation & purification ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/virology ; Humans ; Lactams, Macrocyclic ; Leucine/analogs & derivatives ; Male ; Middle Aged ; Proline/analogs & derivatives ; Pyrrolidines ; Quinoxalines/adverse effects ; RNA, Viral/blood ; Sulfonamides/adverse effects ; Sustained Virologic Response ; Treatment Failure ; Treatment Outcome ; Young Adult

المؤلفون: Chayama K; Hiroshima University Hospital, Hiroshima, Japan. chayama@hiroshima-u.ac.jp., Suzuki F; Toranomon Hospital, Tokyo, Japan., Karino Y; JA Hokkaido P.W.F.A.C Sapporo-Kosei General Hospital, Sapporo, Japan., Kawakami Y; Hiroshima University Hospital, Hiroshima, Japan., Sato K; Gunma University Hospital, Maebashi, Japan., Atarashi T; JA Hokkaido P.W.F.A.C Obihiro-Kosei General Hospital, Obihiro, Japan., Naganuma A; NHO Takasaki General Medical Center, Takasaki, Japan., Watanabe T; St. Marianna University School of Medicine, Kawasaki, Japan., Eguchi Y; Saga University Hospital, Saga, Japan., Yoshiji H; Nara Medical University Hospital, Kashihara, Japan., Seike M; Oita University Hospital, Yufu, Japan., Takei Y; Mie University Hospital, Tsu, Japan., Kato K; AbbVie Inc, North Chicago, IL, USA., Alves K; AbbVie Inc, North Chicago, IL, USA., Burroughs M; AbbVie Inc, North Chicago, IL, USA., Redman R; AbbVie Inc, North Chicago, IL, USA., Pugatch DL; AbbVie Inc, North Chicago, IL, USA., Pilot-Matias TJ; AbbVie Inc, North Chicago, IL, USA., Krishnan P; AbbVie Inc, North Chicago, IL, USA., Oberoi RK; AbbVie Inc, North Chicago, IL, USA., Xie W; AbbVie Inc, North Chicago, IL, USA., Kumada H; Toranomon Hospital, Tokyo, Japan.

المصدر: Journal of gastroenterology [J Gastroenterol] 2018 Apr; Vol. 53 (4), pp. 557-565. Date of Electronic Publication: 2017 Sep 25.

نوع المنشور: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial

بيانات الدورية: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*therapeutic use , Benzimidazoles/*therapeutic use , Hepatitis C, Chronic/*drug therapy , Liver Cirrhosis/*drug therapy , Quinoxalines/*therapeutic use , Sulfonamides/*therapeutic use, Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Aminoisobutyric Acids ; Anilides/therapeutic use ; Antiviral Agents/adverse effects ; Antiviral Agents/blood ; Benzimidazoles/adverse effects ; Benzimidazoles/blood ; Carbamates/therapeutic use ; Cyclopropanes ; Drug Administration Schedule ; Drug Combinations ; Drug Therapy, Combination ; Female ; Hepacivirus/genetics ; Hepacivirus/isolation & purification ; Hepatitis C, Chronic/blood ; Hepatitis C, Chronic/complications ; Hepatitis C, Chronic/virology ; Humans ; Lactams, Macrocyclic ; Leucine/analogs & derivatives ; Liver Cirrhosis/blood ; Liver Cirrhosis/virology ; Macrocyclic Compounds/therapeutic use ; Male ; Middle Aged ; Proline/analogs & derivatives ; Pyrrolidines ; Quinoxalines/adverse effects ; Quinoxalines/blood ; RNA, Viral/blood ; Ritonavir/therapeutic use ; Sulfonamides/adverse effects ; Sulfonamides/blood ; Sustained Virologic Response ; Valine ; Viral Nonstructural Proteins/genetics

المؤلفون: Tamaki Y; Division of Metabolism and Biosystemic Science, Department of Internal Medicine, Asahikawa Medical College, Asahikawa, Hokkaido, Japan., Nakade Y, Yamauchi T, Makino Y, Yokohama S, Okada M, Aso K, Kanamori H, Ohashi T, Sato K, Nakao H, Haneda M, Yoneda M

المصدر: Journal of gastroenterology [J Gastroenterol] 2013 Apr; Vol. 48 (4), pp. 491-503. Date of Electronic Publication: 2012 Aug 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer International Country of Publication: Japan NLM ID: 9430794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-5922 (Electronic) Linking ISSN: 09441174 NLM ISO Abbreviation: J Gastroenterol Subsets: MEDLINE

مواضيع طبية MeSH: Angiotensin II Type 1 Receptor Blockers/*therapeutic use , Anticarcinogenic Agents/*therapeutic use , Benzimidazoles/*therapeutic use , Benzoates/*therapeutic use , Carcinoma, Hepatocellular/*prevention & control , Fatty Liver/*drug therapy , Liver Neoplasms, Experimental/*prevention & control, Amino Acids/administration & dosage ; Animals ; Carcinoma, Hepatocellular/etiology ; Cell Transformation, Neoplastic/drug effects ; Choline Deficiency/complications ; Diet/adverse effects ; Drug Evaluation, Preclinical/methods ; Fatty Liver/complications ; Fatty Liver/metabolism ; Fatty Liver/pathology ; Gene Expression Regulation/drug effects ; Hypoxia-Inducible Factor 1, alpha Subunit/biosynthesis ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Liver/blood supply ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Liver Neoplasms, Experimental/etiology ; Male ; Neovascularization, Pathologic/etiology ; Neovascularization, Pathologic/prevention & control ; Non-alcoholic Fatty Liver Disease ; Rats ; Rats, Wistar ; Telmisartan ; Vascular Endothelial Growth Factor A/biosynthesis ; Vascular Endothelial Growth Factor A/genetics