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تسجيل الدخول للوصول الكامل.

المؤلفون: Hari M; Discovery Oncology, Wyeth, 401 North Middletown Road, Room 4709, Building 200, Pearl River, NY 10965, USA., Loganzo F, Annable T, Tan X, Musto S, Morilla DB, Nettles JH, Snyder JP, Greenberger LM

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2006 Feb; Vol. 5 (2), pp. 270-8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*therapeutic use , Carcinoma, Squamous Cell/*drug therapy , Drug Resistance, Neoplasm/*genetics , Paclitaxel/*therapeutic use , Tubulin/*genetics, ATP Binding Cassette Transporter, Subfamily B, Member 1/antagonists & inhibitors ; Amino Acid Substitution/genetics ; Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Aspartic Acid/chemistry ; Aspartic Acid/genetics ; Carcinoma, Squamous Cell/genetics ; Cell Line, Tumor ; Docetaxel ; Epothilones/chemistry ; Epothilones/therapeutic use ; Glutamic Acid/chemistry ; Glutamic Acid/genetics ; Humans ; Mice ; Mice, Nude ; Microtubules/genetics ; Microtubules/metabolism ; Paclitaxel/analogs & derivatives ; Paclitaxel/chemistry ; Point Mutation ; Protein Conformation ; Taxoids/chemistry ; Taxoids/therapeutic use ; Tubulin/chemistry ; Verapamil/analogs & derivatives ; Verapamil/pharmacology

المؤلفون: Loganzo F; Oncology Research, Wyeth Research, 401 North Middletown Road, 200/4709, Pearl River, NY 10965, USA. loganzf@wyeth.com, Hari M, Annable T, Tan X, Morilla DB, Musto S, Zask A, Kaplan J, Minnick AA Jr, May MK, Ayral-Kaloustian S, Poruchynsky MS, Fojo T, Greenberger LM

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2004 Oct; Vol. 3 (10), pp. 1319-27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm* , Point Mutation*, Antineoplastic Agents/*pharmacology , Oligopeptides/*pharmacology , Tubulin/*metabolism, ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; ATP Binding Cassette Transporter, Subfamily G, Member 2 ; ATP-Binding Cassette Transporters/biosynthesis ; Adenosine Triphosphate/chemistry ; Alanine/chemistry ; Animals ; Cell Line, Tumor ; Cell Proliferation ; Codon ; DNA Damage ; DNA, Complementary/metabolism ; Depsipeptides ; Dimerization ; Doxorubicin/pharmacology ; Humans ; Mice ; Mice, Nude ; Mitoxantrone/pharmacology ; Models, Molecular ; Multidrug Resistance-Associated Proteins/biosynthesis ; Mutation ; Neoplasm Proteins/biosynthesis ; Neoplasm Transplantation ; Protein Conformation ; Sequence Analysis, DNA ; Sodium Azide/pharmacology ; Time Factors ; Tubulin/chemistry ; Vinblastine/pharmacology

المؤلفون: Sampath D; Wyeth Research, Department of Oncology, Pearl River, NY 10965, USA. sampatd1@wyeth.com, Discafani CM, Loganzo F, Beyer C, Liu H, Tan X, Musto S, Annable T, Gallagher P, Rios C, Greenberger LM

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2003 Sep; Vol. 2 (9), pp. 873-84.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Print ISSN: 1535-7163 (Print) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*pharmacology , Neoplasms, Experimental/*pathology , Paclitaxel/*pharmacology , Taxoids/*pharmacology, ATP Binding Cassette Transporter, Subfamily B/antagonists & inhibitors ; ATP Binding Cassette Transporter, Subfamily B/metabolism ; Administration, Oral ; Animals ; Cell Division/drug effects ; Docetaxel ; Female ; Humans ; Inhibitory Concentration 50 ; Mice ; Mice, Nude ; Microtubules/drug effects ; Neoplasms, Experimental/metabolism ; Paclitaxel/analogs & derivatives ; Tubulin/biosynthesis ; Tubulin/drug effects ; Tubulin/isolation & purification ; Tumor Cells, Cultured