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المصدر: Molecules
Volume 25
Issue 11
Molecules, Vol 25, Iss 2593, p 2593 (2020)مصطلحات موضوعية: Models, Molecular, Protein Conformation, Pharmaceutical Science, Pyrazole, 01 natural sciences, DNA gyrase, Analytical Chemistry, chemistry.chemical_compound, Amide, Drug Discovery, Dihydrofolate reductase, Moiety, Topoisomerase II Inhibitors, Schiff base, biology, Molecular Structure, Hep G2 Cells, DHFR, Anti-Bacterial Agents, Molecular Docking Simulation, Chemistry (miscellaneous), Enzyme inhibitor, MCF-7 Cells, Molecular Medicine, Schiff bases, Bacillus subtilis, Staphylococcus aureus, Stereochemistry, enzyme inhibitor, Microbial Sensitivity Tests, 010402 general chemistry, Article, lcsh:QD241-441, Structure-Activity Relationship, Bacterial Proteins, lcsh:Organic chemistry, antiproliferative, Cell Line, Tumor, Escherichia coli, Humans, Physical and Theoretical Chemistry, Cell Proliferation, pyrazole moiety, Binding Sites, 010405 organic chemistry, Organic Chemistry, Active site, molecular docking, 0104 chemical sciences, Tetrahydrofolate Dehydrogenase, chemistry, biology.protein, Folic Acid Antagonists, Pyrazoles, antimicrobial, Drug Screening Assays, Antitumor
وصف الملف: application/pdf
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المؤلفون: Amnon Kohen, Kalani Karunaratne, Michael Choi
المصدر: Molecules, Vol 21, Iss 5, p 654 (2016)
Molecules (Basel, Switzerland)مصطلحات موضوعية: 0301 basic medicine, Pharmaceutical Science, mechanism, Flavin group, thymidylate synthase, Biology, 010402 general chemistry, Infections, 01 natural sciences, Thymidylate synthase, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, lcsh:Organic chemistry, Multienzyme Complexes, Flavins, antibiotic, Drug Discovery, Dihydrofolate reductase, Thymidine Monophosphate, Humans, Physical and Theoretical Chemistry, chemistry.chemical_classification, Thymidine monophosphate, Bacteria, Organic Chemistry, biology.organism_classification, flavin, 0104 chemical sciences, 3. Good health, Anti-Bacterial Agents, De novo synthesis, Kinetics, Tetrahydrofolate Dehydrogenase, enzyme, 030104 developmental biology, Enzyme, Biochemistry, chemistry, Chemistry (miscellaneous), biology.protein, Molecular Medicine, DNA
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المؤلفون: Mary Henry, Richard A. Bunce, William W. Barrow, Christina R. Bourne, K. Darrell Berlin, Esther W. Barrow, Philip C. Bourne, N. Prasad Muddala, Baskar Nammalwar
المصدر: Molecules
Volume 19
Issue 3
Pages 3231-3246
Molecules (Basel, Switzerland)
Molecules, Vol 19, Iss 3, Pp 3231-3246 (2014)مصطلحات موضوعية: Models, Molecular, antibiotic resistance, Antibiotics, Molecular Conformation, Pharmaceutical Science, 2,4-diaminopyrimidine, 01 natural sciences, Analytical Chemistry, Stereocenter, chemistry.chemical_compound, Heck reaction, dihydrofolate reductase (DHFR), Drug Discovery, antifolates, Moiety, media_common, 0303 health sciences, biology, Biological activity, Gram-positive bacteria, 3. Good health, Bacillus anthracis, Biochemistry, Chemistry (miscellaneous), Molecular Medicine, Protein Binding, Drug, medicine.drug_class, media_common.quotation_subject, Microbial Sensitivity Tests, Article, lcsh:QD241-441, 03 medical and health sciences, Antibiotic resistance, lcsh:Organic chemistry, medicine, Physical and Theoretical Chemistry, Binding Sites, 010405 organic chemistry, 030306 microbiology, Organic Chemistry, biology.organism_classification, 0104 chemical sciences, Tetrahydrofolate Dehydrogenase, Pyrimidines, Diaminopyrimidine, chemistry, Folic Acid Antagonists
وصف الملف: application/pdf
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