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المؤلفون: Zheng W; Department of Immunology, Harvard Medical School, Boston, MA, USA., Zhao W; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, School of Medicine, Sun Yat-sen University, Guangzhou, China.; Department of Microbiology, Harvard Medical School, Boston, MA, USA., Wu M; Department of Immunology, Harvard Medical School, Boston, MA, USA., Song X; Department of Immunology, Harvard Medical School, Boston, MA, USA., Caro F; Department of Microbiology, Harvard Medical School, Boston, MA, USA., Sun X; Department of Immunology, Harvard Medical School, Boston, MA, USA., Gazzaniga F; Department of Immunology, Harvard Medical School, Boston, MA, USA., Stefanetti G; Department of Immunology, Harvard Medical School, Boston, MA, USA.; Department of Chemistry, University of Milan, Milan, Italy., Oh S; Department of Immunology, Harvard Medical School, Boston, MA, USA., Mekalanos JJ; Department of Microbiology, Harvard Medical School, Boston, MA, USA., Kasper DL; Department of Immunology, Harvard Medical School, Boston, MA, USA. dennis_kasper@hms.harvard.edu.

المصدر: Nature [Nature] 2020 Jan; Vol. 577 (7791), pp. 543-548. Date of Electronic Publication: 2020 Jan 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies/*immunology , Enterotoxigenic Escherichia coli/*immunology , Escherichia coli Infections/*immunology , Escherichia coli Infections/*prevention & control , Immunity, Maternally-Acquired/*immunology , Infant, Newborn/*immunology , Microbiota/*immunology , Milk, Human/*immunology, Animals ; Antibodies/blood ; Antibodies/metabolism ; Breast Feeding ; Cross Reactions/immunology ; Escherichia coli Infections/microbiology ; Female ; Humans ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Immunoglobulin G/metabolism ; Male ; Mice ; Mothers ; Pantoea/immunology ; Receptors, Fc/immunology ; Receptors, Fc/metabolism ; Symbiosis/immunology

المؤلفون: Rivera-Chávez F; Department of Microbiology, Harvard Medical School, Boston, MA, USA., Mekalanos JJ; Department of Microbiology, Harvard Medical School, Boston, MA, USA. john_mekalanos@hms.harvard.edu.

المصدر: Nature [Nature] 2019 Aug; Vol. 572 (7768), pp. 244-248. Date of Electronic Publication: 2019 Jul 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cholera Toxin/*pharmacology , Host-Pathogen Interactions/*drug effects , Vibrio cholerae/*drug effects , Vibrio cholerae/*metabolism, Animals ; Cholera/metabolism ; Cholera/microbiology ; Citric Acid Cycle/drug effects ; Fatty Acids/chemistry ; Fatty Acids/metabolism ; Heme/metabolism ; Lactic Acid/metabolism ; Mice ; Rabbits ; Sequence Analysis, RNA ; Transcriptome/drug effects ; Transcriptome/genetics ; Vibrio cholerae/genetics

المؤلفون: Whiteley AT; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Eaglesham JB; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., de Oliveira Mann CC; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Morehouse BR; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Lowey B; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Nieminen EA; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA., Danilchanka O; Department of Microbiology, Harvard Medical School, Boston, MA, USA.; Merck Research Laboratories, Merck & Co. Inc., Kenilworth, NJ, USA., King DS; HHMI Mass Spectrometry Laboratory, University of California, Berkeley, Berkeley, CA, USA., Lee ASY; Department of Biology, Brandeis University, Waltham, MA, USA., Mekalanos JJ; Department of Microbiology, Harvard Medical School, Boston, MA, USA. john_mekalanos@hms.harvard.edu., Kranzusch PJ; Department of Microbiology, Harvard Medical School, Boston, MA, USA. philip_kranzusch@dfci.harvard.edu.; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA, USA. philip_kranzusch@dfci.harvard.edu.; Parker Institute for Cancer Immunotherapy at Dana-Farber Cancer Institute, Boston, MA, USA. philip_kranzusch@dfci.harvard.edu.

المصدر: Nature [Nature] 2019 Mar; Vol. 567 (7747), pp. 194-199. Date of Electronic Publication: 2019 Feb 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*metabolism , Nucleotides/*biosynthesis , Nucleotides/*metabolism , Nucleotidyltransferases/*chemistry , Nucleotidyltransferases/*metabolism, Animals ; Crystallography, X-Ray ; Dinucleoside Phosphates/biosynthesis ; Dinucleoside Phosphates/metabolism ; HEK293 Cells ; Humans ; Mice ; Nucleotides/chemistry ; Nucleotidyltransferases/genetics ; Operon/genetics ; Symbiosis

المؤلفون: Meeske AJ; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Riley EP; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Robins WP; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Uehara T; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Mekalanos JJ; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Kahne D; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Ave, Boston, Massachusetts 02115, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA., Walker S; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Ave, Boston, Massachusetts 02115, USA.; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA., Kruse AC; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 250 Longwood Ave, Boston, Massachusetts 02115, USA., Bernhardt TG; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA., Rudner DZ; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

المصدر: Nature [Nature] 2016 Sep 29; Vol. 537 (7622), pp. 634-638. Date of Electronic Publication: 2016 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Polymerization*, Bacillus subtilis/*enzymology , Bacterial Proteins/*metabolism , Cell Wall/*metabolism , Peptidoglycan/*biosynthesis , Peptidoglycan Glycosyltransferase/*metabolism, Anti-Bacterial Agents/pharmacology ; Bacillus subtilis/cytology ; Bacillus subtilis/drug effects ; Bacillus subtilis/growth & development ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Cell Division ; Cell Wall/chemistry ; Drug Design ; Drug Resistance, Bacterial/drug effects ; Mutation ; Oligosaccharides/pharmacology ; Penicillin-Binding Proteins/classification ; Penicillin-Binding Proteins/genetics ; Penicillin-Binding Proteins/metabolism ; Peptidoglycan Glycosyltransferase/chemistry ; Peptidoglycan Glycosyltransferase/genetics ; Phenotype

المؤلفون: Shneider MM; École Polytechnique Fédérale de Lausanne (EPFL), BSP-415, 1015 Lausanne, Switzerland.; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Laboratory of Molecular Bioengineering, 16/10 Miklukho-Maklaya St., 117997 Moscow, Russia., Buth SA; École Polytechnique Fédérale de Lausanne (EPFL), BSP-415, 1015 Lausanne, Switzerland., Ho BT; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Basler M; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Mekalanos JJ; Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Leiman PG; École Polytechnique Fédérale de Lausanne (EPFL), BSP-415, 1015 Lausanne, Switzerland.

المصدر: Nature [Nature] 2013 Aug 15; Vol. 500 (7462), pp. 350-353. Date of Electronic Publication: 2013 Aug 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*chemistry , Bacterial Proteins/*metabolism , Bacterial Secretion Systems/*genetics , Microsatellite Repeats/*physiology, Acinetobacter/genetics ; Acinetobacter/metabolism ; Protein Binding ; Vibrio cholerae/genetics ; Vibrio cholerae/metabolism

المؤلفون: Basler M; Department of Microbiology and Immunobiology, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA., Pilhofer M, Henderson GP, Jensen GJ, Mekalanos JJ

المصدر: Nature [Nature] 2012 Feb 26; Vol. 483 (7388), pp. 182-6. Date of Electronic Publication: 2012 Feb 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins/*chemistry , Bacterial Proteins/*ultrastructure , Bacterial Secretion Systems/*physiology , Bacteriophages/*chemistry , Vibrio cholerae/*chemistry , Vibrio cholerae/*metabolism, Bacterial Proteins/metabolism ; Bacteriophages/physiology ; Cell Membrane/metabolism ; Cryoelectron Microscopy ; Electron Microscope Tomography ; Microscopy, Fluorescence ; Vibrio cholerae/cytology ; Vibrio cholerae/ultrastructure

المؤلفون: Hassan F; Molecular Genetics Laboratory, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka-1212, Bangladesh., Kamruzzaman M, Mekalanos JJ, Faruque SM

المصدر: Nature [Nature] 2010 Oct 21; Vol. 467 (7318), pp. 982-5. Date of Electronic Publication: 2010 Oct 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Viral/*genetics , Inovirus/*genetics , Inovirus/*physiology , Vibrio cholerae/*genetics , Vibrio cholerae/*virology , Virus Integration/*genetics, Attachment Sites, Microbiological/genetics ; Base Sequence ; Cholera/epidemiology ; Cholera/microbiology ; Cholera Toxin/genetics ; Evolution, Molecular ; Genes, Bacterial/genetics ; Genome, Bacterial/genetics ; Genome, Viral/genetics ; Helper Viruses/genetics ; Helper Viruses/physiology ; Humans ; Inovirus/pathogenicity ; Lysogeny/genetics ; Lysogeny/physiology ; Molecular Sequence Data ; Phenotype ; Plasmids/genetics ; Prophages/genetics ; Prophages/physiology ; Recombination, Genetic/genetics ; Transduction, Genetic ; Vibrio cholerae/classification ; Vibrio cholerae/pathogenicity

المؤلفون: Mekalanos JJ, Swartz DJ, Pearson GD, Harford N, Groyne F, de Wilde M

المصدر: Nature [Nature] 1983 Dec 8-14; Vol. 306 (5943), pp. 551-7.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Print ISSN: 0028-0836 (Print) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Cholera Vaccines* , Recombination, Genetic*, Cholera Toxin/*genetics, Base Sequence ; Cloning, Molecular ; Gene Expression Regulation ; Operon ; Vibrio cholerae/genetics