المؤلفون: Hakim CH; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA.; National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA., Kumar SRP; Department of Pediatrics, Indiana University, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, Indiana University, Indianapolis, IN, USA., Pérez-López DO; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Wasala NB; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Zhang D; Department of Physics, The University of Missouri, Columbia, MO, USA.; Department of Biochemistry, The University of Missouri, Columbia, MO, USA.; Institute for Data Science and Informatics, The University of Missouri, Columbia, MO, USA., Yue Y; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Teixeira J; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Pan X; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Zhang K; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Million ED; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Nelson CE; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies Biology, Duke University, Durham, NC, USA., Metzger S; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Han J; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Louderman JA; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Schmidt F; Department of Infectious Diseases/Virology, University of Heidelberg, Heidelberg, Germany.; Cluster of Excellence CellNetworks, University of Heidelberg, Heidelberg, Germany.; BioQuant, University of Heidelberg, Heidelberg, Germany., Feng F; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA., Grimm D; Department of Infectious Diseases/Virology, University of Heidelberg, Heidelberg, Germany.; Cluster of Excellence CellNetworks, University of Heidelberg, Heidelberg, Germany.; BioQuant, University of Heidelberg, Heidelberg, Germany., Smith BF; Department of Pathobiology, Auburn University, Auburn, AL, USA.; Scott-Ritchey Research Center, Auburn University, Auburn, AL, USA., Yao G; Department of Biomedical, Biological & Chemical Engineering, The University of Missouri, Columbia, MO, USA., Yang NN; National Center for Advancing Translational Sciences, NIH, Rockville, MD, USA., Gersbach CA; Department of Biomedical Engineering, Duke University, Durham, NC, USA.; Center for Advanced Genomic Technologies Biology, Duke University, Durham, NC, USA.; Department of Surgery, Duke University Medical Center, Durham, NC, USA., Chen SJ; Department of Physics, The University of Missouri, Columbia, MO, USA.; Department of Biochemistry, The University of Missouri, Columbia, MO, USA.; Institute for Data Science and Informatics, The University of Missouri, Columbia, MO, USA., Herzog RW; Department of Pediatrics, Indiana University, Indianapolis, IN, USA.; Herman B Wells Center for Pediatric Research, Indiana University, Indianapolis, IN, USA., Duan D; Department of Molecular Microbiology and Immunology, The University of Missouri, Columbia, MO, USA. duand@missouri.edu.; Department of Biomedical, Biological & Chemical Engineering, The University of Missouri, Columbia, MO, USA. duand@missouri.edu.; Department of Neurology, The University of Missouri, Columbia, MO, USA. duand@missouri.edu.; Department of Biomedical Sciences, The University of Missouri, Columbia, MO, USA. duand@missouri.edu.

المصدر: Nature communications [Nat Commun] 2021 Nov 24; Vol. 12 (1), pp. 6769. Date of Electronic Publication: 2021 Nov 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems/*immunology , Genetic Therapy/*adverse effects , Genetic Vectors/*immunology , Muscle, Skeletal/*immunology , Muscular Dystrophy, Duchenne/*therapy, Animals ; CRISPR-Cas Systems/genetics ; Dependovirus/genetics ; Disease Models, Animal ; Dogs ; Dystrophin/genetics ; Dystrophin/immunology ; Gene Editing/methods ; Genes, Reporter/genetics ; Genes, Reporter/immunology ; Genetic Therapy/methods ; Genetic Vectors/administration & dosage ; Humans ; Muscle, Skeletal/pathology ; Muscular Dystrophy, Duchenne/genetics ; Muscular Dystrophy, Duchenne/immunology ; Muscular Dystrophy, Duchenne/pathology ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/immunology