المؤلفون: Quan C; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Du Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Li M; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Wang R; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Ouyang Q; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Su S; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Zhu S; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Chen Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Sheng Y; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Chen L; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Wang H; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University, 518055, Shenzhen, China., Campbell DG; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK., MacKintosh C; Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK., Yang Z; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Ouyang K; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University, 518055, Shenzhen, China., Wang HY; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China. wanghy@nicemice.cn., Chen S; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China. schen6@163.com.; Nanjing Biomedical Research Institute, Nanjing University, 210061, Nanjing, China. schen6@163.com.

المصدر: Nature communications [Nat Commun] 2020 May 04; Vol. 11 (1), pp. 2186. Date of Electronic Publication: 2020 May 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis* , Insulin Resistance*, Calcium/*metabolism , Diabetic Cardiomyopathies/*metabolism , Muscle Proteins/*metabolism , Myosin-Light-Chain Kinase/*metabolism , Proto-Oncogene Proteins c-akt/*metabolism, Animals ; Diabetic Cardiomyopathies/genetics ; Humans ; Hypoglycemic Agents/metabolism ; Hypoglycemic Agents/pharmacology ; Insulin/metabolism ; Insulin/pharmacology ; Mice, Inbred C57BL ; Mice, Transgenic ; Muscle Proteins/genetics ; Mutation ; Myosin-Light-Chain Kinase/genetics ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/genetics ; Sarcoplasmic Reticulum/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Signal Transduction/genetics