المؤلفون: Tajima K; UCSF Diabetes Center, San Francisco, CA, 94143, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA, 94143, USA.; Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA., Ikeda K; UCSF Diabetes Center, San Francisco, CA, 94143, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA, 94143, USA.; Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA.; Department of Molecular Endocrinology and Metabolism, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Tanabe Y; Department of Electrical Engineering, Stanford University, Stanford, CA, 94305, USA., Thomson EA; Department of Electrical Engineering, Stanford University, Stanford, CA, 94305, USA., Yoneshiro T; UCSF Diabetes Center, San Francisco, CA, 94143, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA, 94143, USA.; Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA., Oguri Y; UCSF Diabetes Center, San Francisco, CA, 94143, USA.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA, 94143, USA.; Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA., Ferro MD; Department of Materials Science and Engineering, Stanford University, Stanford, CA, 94305, USA., Poon ASY; Department of Electrical Engineering, Stanford University, Stanford, CA, 94305, USA. adapoon@stanford.edu.; Chan Zuckerberg Biohub, San Francisco, CA, 94158, USA. adapoon@stanford.edu., Kajimura S; UCSF Diabetes Center, San Francisco, CA, 94143, USA. shingo.kajimura@ucsf.edu.; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, San Francisco, CA, 94143, USA. shingo.kajimura@ucsf.edu.; Department of Cell and Tissue Biology, University of California, San Francisco, CA, 94143, USA. shingo.kajimura@ucsf.edu.

المصدر: Nature communications [Nat Commun] 2020 Apr 07; Vol. 11 (1), pp. 1730. Date of Electronic Publication: 2020 Apr 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adipocytes/*metabolism , Adipose Tissue/*metabolism , Channelrhodopsins/*metabolism , Obesity/*therapy , Optogenetics/*instrumentation , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*metabolism , Thermogenesis/*radiation effects, Adipocytes/radiation effects ; Adipose Tissue/radiation effects ; Animals ; Body Weight/physiology ; Body Weight/radiation effects ; Calcium/metabolism ; Cells, Cultured ; Channelrhodopsins/radiation effects ; Channelrhodopsins/therapeutic use ; Diet ; Energy Metabolism/radiation effects ; Locomotion ; Male ; Mice ; Mice, Knockout ; Obesity/metabolism ; Optogenetics/methods ; Oxygen Consumption ; Receptors, Adrenergic, beta/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Thermogenesis/physiology

المؤلفون: Li Y; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Ivica NA; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Dong T; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Papageorgiou DP; Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., He Y; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Brown DR; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Kleyman M; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Hu G; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Chen WW; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.; Boston Combined Residency Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA, 02115, USA., Sullivan LB; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Del Rosario A; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Hammond PT; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Vander Heiden MG; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Chen J; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. jchen@mit.edu.

المصدر: Nature communications [Nat Commun] 2020 Sep 24; Vol. 11 (1), pp. 4837. Date of Electronic Publication: 2020 Sep 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphate/*metabolism , Heme/*metabolism , Membrane Transport Proteins/*metabolism , Mitochondria/*metabolism , Receptors, Virus/*metabolism , Thermogenesis/*physiology, Animals ; Cytochrome-c Oxidase Deficiency ; Electron Transport Complex III ; Electron Transport Complex IV ; Energy Metabolism/physiology ; Gene Knockout Techniques ; HEK293 Cells ; Humans ; Membrane Transport Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondrial Membranes/metabolism ; Protein Domains ; Receptors, Virus/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Signal Transduction ; THP-1 Cells