المؤلفون: Quan C; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Du Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Li M; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Wang R; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Ouyang Q; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Su S; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Zhu S; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Chen Q; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Sheng Y; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Chen L; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Wang H; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University, 518055, Shenzhen, China., Campbell DG; MRC Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK., MacKintosh C; Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee, DD1 5EH, Scotland, UK., Yang Z; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China., Ouyang K; Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University, 518055, Shenzhen, China., Wang HY; MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, 210061, Nanjing, China. wanghy@nicemice.cn., Chen S; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Model Animal Research Center, Nanjing University, 210061, Nanjing, China. schen6@163.com.; Nanjing Biomedical Research Institute, Nanjing University, 210061, Nanjing, China. schen6@163.com.

المصدر: Nature communications [Nat Commun] 2020 May 04; Vol. 11 (1), pp. 2186. Date of Electronic Publication: 2020 May 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis* , Insulin Resistance*, Calcium/*metabolism , Diabetic Cardiomyopathies/*metabolism , Muscle Proteins/*metabolism , Myosin-Light-Chain Kinase/*metabolism , Proto-Oncogene Proteins c-akt/*metabolism, Animals ; Diabetic Cardiomyopathies/genetics ; Humans ; Hypoglycemic Agents/metabolism ; Hypoglycemic Agents/pharmacology ; Insulin/metabolism ; Insulin/pharmacology ; Mice, Inbred C57BL ; Mice, Transgenic ; Muscle Proteins/genetics ; Mutation ; Myosin-Light-Chain Kinase/genetics ; Phosphorylation/drug effects ; Proto-Oncogene Proteins c-akt/genetics ; Sarcoplasmic Reticulum/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Signal Transduction/genetics

المؤلفون: Li Y; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Ivica NA; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Dong T; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Papageorgiou DP; Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., He Y; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Brown DR; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Kleyman M; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Hu G; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Chen WW; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.; Boston Combined Residency Program, Department of Pediatrics, Boston Children's Hospital, Boston, MA, 02115, USA., Sullivan LB; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Del Rosario A; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Hammond PT; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA., Vander Heiden MG; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.; Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Chen J; Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA. jchen@mit.edu.

المصدر: Nature communications [Nat Commun] 2020 Sep 24; Vol. 11 (1), pp. 4837. Date of Electronic Publication: 2020 Sep 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphate/*metabolism , Heme/*metabolism , Membrane Transport Proteins/*metabolism , Mitochondria/*metabolism , Receptors, Virus/*metabolism , Thermogenesis/*physiology, Animals ; Cytochrome-c Oxidase Deficiency ; Electron Transport Complex III ; Electron Transport Complex IV ; Energy Metabolism/physiology ; Gene Knockout Techniques ; HEK293 Cells ; Humans ; Membrane Transport Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondrial Membranes/metabolism ; Protein Domains ; Receptors, Virus/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Signal Transduction ; THP-1 Cells

المؤلفون: Jin S; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, National Research Center for Environmental Health, Marchioninistrasse 25, 81377 Munich, Germany., Kim J; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, National Research Center for Environmental Health, Marchioninistrasse 25, 81377 Munich, Germany., Willert T; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, National Research Center for Environmental Health, Marchioninistrasse 25, 81377 Munich, Germany., Klein-Rodewald T; Institute of Pathology, Helmholtz Zentrum München, National Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, 81377 Munich, Germany., Garcia-Dominguez M; 1] Developmental Biology Section, Ecole Normale Supérieure, Rue d'Ulm 46, 75230 Paris, France [2] Stem Cells Department, CABIMER (CISC), Av Américo Vespucio, 41092 Sevilla, Spain., Mosqueira M; Medical Biophysics Unit, Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, 69120 Heidelberg, Germany., Fink R; Medical Biophysics Unit, Institute of Physiology and Pathophysiology, University of Heidelberg, Im Neuenheimer Feld 326, 69120 Heidelberg, Germany., Esposito I; 1] Institute of Pathology, Helmholtz Zentrum München, National Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, 81377 Munich, Germany [2] Institute of Pathology, Technische Universität München, Ismaningerstrasse 22, 81675 Munich, Germany., Hofbauer LC; Division of Endocrinology, Diabetes and Metabolic Bone Diseases, Department of Medicine III, TU Dresden Medical Center, Fetscherstrasse 74, 01307 Dresden, Germany., Charnay P; Developmental Biology Section, Ecole Normale Supérieure, Rue d'Ulm 46, 75230 Paris, France., Kieslinger M; Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, National Research Center for Environmental Health, Marchioninistrasse 25, 81377 Munich, Germany.

المصدر: Nature communications [Nat Commun] 2014 May 02; Vol. 5, pp. 3793. Date of Electronic Publication: 2014 May 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Muscle Relaxation/*physiology , MyoD Protein/*physiology , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*physiology , Transcription Factors/*physiology, Animals ; Mice ; Mice, Knockout ; Respiratory Insufficiency/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics

المؤلفون: Duan J; Centres for Discovery Brain Sciences and Cardiovascular Sciences, College of Medicine and Veterinary Medicine, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK., Navarro-Dorado J; Centres for Discovery Brain Sciences and Cardiovascular Sciences, College of Medicine and Veterinary Medicine, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK., Clark JH; Centres for Discovery Brain Sciences and Cardiovascular Sciences, College of Medicine and Veterinary Medicine, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK., Kinnear NP; Centres for Discovery Brain Sciences and Cardiovascular Sciences, College of Medicine and Veterinary Medicine, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK., Meinke P; Wellcome Centre for Cell Biology, Michael Swann Building, University of Edinburgh, Edinburgh, EH9 3BF, UK., Schirmer EC; Wellcome Centre for Cell Biology, Michael Swann Building, University of Edinburgh, Edinburgh, EH9 3BF, UK., Evans AM; Centres for Discovery Brain Sciences and Cardiovascular Sciences, College of Medicine and Veterinary Medicine, Hugh Robson Building, University of Edinburgh, Edinburgh, EH8 9XD, UK. mark.evans@ed.ac.uk.

المصدر: Nature communications [Nat Commun] 2019 May 24; Vol. 10 (1), pp. 2299. Date of Electronic Publication: 2019 May 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Video-Audio Media

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Calcium Signaling/*physiology , Cytosol/*metabolism, Animals ; Cell Membrane/metabolism ; Cell Proliferation/physiology ; Cells, Cultured ; Male ; Muscle Cells/physiology ; Muscle Contraction/physiology ; Muscle, Skeletal/cytology ; Muscle, Skeletal/physiology ; Nuclear Envelope/metabolism ; Primary Cell Culture ; Rats ; Rats, Sprague-Dawley ; Ryanodine Receptor Calcium Release Channel/metabolism ; Sarcoplasmic Reticulum/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism

المؤلفون: Hu N; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Harvard Medical School, Boston, MA, 02114, USA., Antoury L; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Harvard Medical School, Boston, MA, 02114, USA., Baran TM; Department of Imaging Sciences, University of Rochester, Rochester, NY, 14642, USA., Mitra S; Department of Imaging Sciences, University of Rochester, Rochester, NY, 14642, USA., Bennett CF; Ionis Pharmaceuticals, Carlsbad, CA, 92010, USA., Rigo F; Ionis Pharmaceuticals, Carlsbad, CA, 92010, USA., Foster TH; Department of Imaging Sciences, University of Rochester, Rochester, NY, 14642, USA., Wheeler TM; Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA. twheeler1@mgh.harvard.edu.; Harvard Medical School, Boston, MA, 02114, USA. twheeler1@mgh.harvard.edu.

المصدر: Nature communications [Nat Commun] 2018 Dec 07; Vol. 9 (1), pp. 5227. Date of Electronic Publication: 2018 Dec 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Alternative Splicing*, Muscles/*drug effects , Myotonic Dystrophy/*drug therapy , Oligonucleotides, Antisense/*pharmacology, Animals ; Disease Models, Animal ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Luminescent Proteins/genetics ; Luminescent Proteins/metabolism ; Mice, Transgenic ; Microscopy, Fluorescence ; Muscles/metabolism ; Muscles/pathology ; Myotonic Dystrophy/genetics ; Myotonic Dystrophy/metabolism ; Outcome Assessment, Health Care/methods ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Spectrometry, Fluorescence

المؤلفون: Voit A; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Patel V; Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Pachon R; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Shah V; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Bakhutma M; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Kohlbrenner E; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., McArdle JJ; Department of Pharmacology, Physiology and Neuroscience, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Dell'Italia LJ; Department of Medicine, University of Alabama at Birmingham, and Birmingham VA Medical Center, Birmingham, AL, 35294, USA., Mendell JR; Department of Pediatrics and Department of Neurology, Ohio State University Research Institute at Nationwide Children's Hospital, Columbus, OH, 43205, USA., Xie LH; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Hajjar RJ; Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Duan D; Department of Molecular Microbiology and Immunology, Neurology, Bioengineering, Biomedical Sciences, The University of Missouri, Columbia, MO, 65212, USA., Fraidenraich D; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA., Babu GJ; Department of Cell Biology and Molecular Medicine, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ, 07103, USA. babugo@njms.rutgers.edu.

المصدر: Nature communications [Nat Commun] 2017 Oct 20; Vol. 8 (1), pp. 1068. Date of Electronic Publication: 2017 Oct 20.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Silencing* , Genetic Therapy*, Cardiomyopathies/*physiopathology , Gene Expression Regulation/*genetics , Muscle Proteins/*genetics , Muscular Dystrophy, Duchenne/*physiopathology , Muscular Dystrophy, Duchenne/*therapy , Proteolipids/*genetics, Animals ; Cardiomyopathies/genetics ; Disease Models, Animal ; Dystrophin/genetics ; Dystrophin/metabolism ; Mice ; Mice, Inbred mdx ; Mice, Knockout ; Muscle Proteins/metabolism ; Muscular Dystrophy, Duchenne/genetics ; Proteolipids/metabolism ; RNA Interference ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/genetics ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism ; Utrophin/genetics ; Utrophin/metabolism

المؤلفون: Mauvezin C; Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, Minnesota 55455, USA., Nagy P; Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Pazmany s. 1/C. 6.520, Budapest H-1117, Hungary., Juhász G; Department of Anatomy, Cell and Developmental Biology, Eötvös Loránd University, Pazmany s. 1/C. 6.520, Budapest H-1117, Hungary., Neufeld TP; Department of Genetics, Cell Biology and Development, University of Minnesota, 6-160 Jackson Hall, 321 Church Street SE, Minneapolis, Minnesota 55455, USA.

المصدر: Nature communications [Nat Commun] 2015 May 11; Vol. 6, pp. 7007. Date of Electronic Publication: 2015 May 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy*/drug effects , Membrane Fusion*/drug effects, Acids/*metabolism , Drosophila melanogaster/*enzymology , Lysosomes/*metabolism , Phagosomes/*metabolism , Vacuolar Proton-Translocating ATPases/*metabolism, Animals ; Drosophila melanogaster/drug effects ; Lysosomes/drug effects ; Lysosomes/ultrastructure ; Macrolides/pharmacology ; Models, Biological ; Phagosomes/drug effects ; Phagosomes/ultrastructure ; Protein Subunits/metabolism ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/antagonists & inhibitors ; Sarcoplasmic Reticulum Calcium-Transporting ATPases/metabolism

المؤلفون: Kho C; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Lee A; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Jeong D; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Oh JG; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Gorski PA; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Fish K; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA., Sanchez R; Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., DeVita RJ; 1] Department of Structural and Chemical Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] Department of Pharmacology and System Therapeutics, Experimental Therapeutics Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Christensen G; Institute for Experimental Medical Research, Oslo University Hospital Ullevål and University of Oslo, Oslo 0450, Norway., Dahl R; Department of Pharmaceutical Science, Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA., Hajjar RJ; Department of Medicine/Cardiology, Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy place, Box 1030, New York, New York 10029, USA.

المصدر: Nature communications [Nat Commun] 2015 Jun 12; Vol. 6, pp. 7229. Date of Electronic Publication: 2015 Jun 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Sumoylation*, Heart Failure/*therapy , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*metabolism, Animals ; Cells, Cultured ; Disease Models, Animal ; Heart Failure/physiopathology ; Hemodynamics ; Humans ; Mice ; Rats

المؤلفون: Sprenger JU; 1] Emmy Noether Group of the DFG, European Heart Research Institute Göttingen, University Medical Center Göttingen, D-37075 Göttingen, Germany [2] Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany [3] Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany., Perera RK; 1] Emmy Noether Group of the DFG, European Heart Research Institute Göttingen, University Medical Center Göttingen, D-37075 Göttingen, Germany [2] Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany [3] Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany., Steinbrecher JH; Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany., Lehnart SE; 1] Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany [2] German Center for Cardiovascular Research (DZHK), D-93053 Regensburg, Germany., Maier LS; Department of Internal Medicine II, University Hospital Regensburg, D-93053 Regensburg, Germany., Hasenfuss G; 1] Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany [2] German Center for Cardiovascular Research (DZHK), D-93053 Regensburg, Germany., Nikolaev VO; 1] Emmy Noether Group of the DFG, European Heart Research Institute Göttingen, University Medical Center Göttingen, D-37075 Göttingen, Germany [2] Department of Cardiology and Pulmonology, Heart Research Center Göttingen, University Medical Center Göttingen, Georg August University, D-37075 Göttingen, Germany [3] Institute of Experimental Cardiovascular Research, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany [4] German Center for Cardiovascular Research (DZHK), D-93053 Regensburg, Germany.

المصدر: Nature communications [Nat Commun] 2015 Apr 28; Vol. 6, pp. 6965. Date of Electronic Publication: 2015 Apr 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Biosensing Techniques*, Cyclic AMP/*metabolism , Heart Diseases/*metabolism , Myocytes, Cardiac/*metabolism , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*metabolism, Adrenergic beta-Agonists ; Animals ; Calcium-Binding Proteins ; Cardiomegaly/etiology ; Cardiomegaly/metabolism ; Cells, Cultured ; Disease Models, Animal ; Female ; Fluorescence Resonance Energy Transfer ; Guanine Nucleotide Exchange Factors ; Heart Diseases/etiology ; Isoproterenol ; Mice, Transgenic ; Phosphoric Diester Hydrolases/metabolism ; Random Allocation

المؤلفون: Traister A; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Li M; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Aafaqi S; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Lu M; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Arab S; University Health Network, University of Toronto, Toronto, Ontario, Canada M5S 2J7., Radisic M; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada M5S 3G9., Gross G; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Guido F; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Sherret J; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Verma S; Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada M5B 1W8., Slorach C; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Mertens L; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Hui W; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8., Roy A; 1] Program in Physiology and Experimental Medicine, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8 [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8., Delgado-Olguín P; 1] Program in Physiology and Experimental Medicine, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8 [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8 [3] Heart &Stroke Richard Lewar Centre of Excellence, Toronto, Ontario, Canada M5B 1W8., Hannigan G; Cell Adhesion Signaling Laboratory, Monash Institute of Medical Research, Monash University, Melbourne, Victoria 3800, Australia., Maynes JT; 1] Department of Anesthesia and Pain Medicine, Division of Molecular Structure and Function, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8 [2] Departments of Anesthesia and Biochemistry, Universtiy of Toronto, Toronto, Ontario, Canada M5S 2J7., Coles JG; Cardiology Division, Department of Paediatrics, Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8.

المصدر: Nature communications [Nat Commun] 2014 Sep 11; Vol. 5, pp. 4533. Date of Electronic Publication: 2014 Sep 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Calcium-Binding Proteins/*metabolism , Mechanotransduction, Cellular/*genetics , Myocardial Contraction/*genetics , Myocytes, Cardiac/*metabolism , Protein Serine-Threonine Kinases/*genetics , Sarcoplasmic Reticulum Calcium-Transporting ATPases/*metabolism, Animals ; Humans ; Induced Pluripotent Stem Cells ; Mechanotransduction, Cellular/physiology ; Mice ; Mice, Knockout ; Myocardial Contraction/physiology ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Sarcoplasmic Reticulum/metabolism