المؤلفون: Troy L. Mitchell, Yang Li, Tom Z. Yuan, Meghah Vuppalapaty, Nikita Tripuraneni, Fowler Tristan William, Sung-Jin Lee, Jingjing Ye, Haili Zhang, Erica S. Rego, Hui Chen, Archana Dilip, Liqin Xie, Helene Baribault, Janda Claudia Yvonne, Wen-Chen Yeh, Shengjiang Tu, Maureen Newman, Brian Ouyang, Devin Mutha

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: 0301 basic medicine, Frizzled, Aging, Science, Osteoporosis, Drug Evaluation, Preclinical, General Physics and Astronomy, 030209 endocrinology & metabolism, Regenerative medicine, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, Young Adult, 0302 clinical medicine, In vivo, Bone Density, Medicine, Animals, Humans, Femur, Bone Resorption, Wnt Signaling Pathway, Osteoporosis, Postmenopausal, Aged, Bone mineral, Phenocopy, Multidisciplinary, Bone Density Conservation Agents, Diphosphonates, business.industry, Wnt signaling pathway, Increased Bone Density, Drug Synergism, General Chemistry, medicine.disease, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, Cancer research, Drug Therapy, Combination, Female, business, Femoral Fractures

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b417c9384484d7b1c272b1f89bb76314
https://doaj.org/article/f832347476cc4872864883076749da99

المؤلفون: Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom

المساهمون: Center of Experimental and Molecular Medicine, CCA - Cancer biology and immunology, Radiotherapy

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, 12(1):3464. Nature Publishing Group
Nature Communications
S-CORT Consortium 2021, ' Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis ', Nature Communications, vol. 12, 3464 . https://doi.org/10.1038/s41467-021-23717-5

مصطلحات موضوعية: 0301 basic medicine, Chemistry(all), MICROSATELLITE INSTABILITY, Carcinogenesis, Colorectal cancer, Cellular differentiation, Receptor, Transforming Growth Factor-beta Type I, General Physics and Astronomy, SESSILE SERRATED ADENOMAS, DISTAL COLON, Kaplan-Meier Estimate, medicine.disease_cause, COLORECTAL-CANCER, 0302 clinical medicine, Transforming Growth Factor beta, Wnt Signaling Pathway, IN-VIVO, Mutation, Multidisciplinary, Cancer stem cells, Wnt signaling pathway, LGR5, Cell Differentiation, Prognosis, Multidisciplinary Sciences, 030220 oncology & carcinogenesis, Colonic Neoplasms, Science & Technology - Other Topics, Stem cell, STEM-CELLS, Signal Transduction, EXPRESSION, Proto-Oncogene Proteins B-raf, Cell Survival, Colon, MAP Kinase Signaling System, Science, INHIBITION, Physics and Astronomy(all), Biology, Article, General Biochemistry, Genetics and Molecular Biology, WNT ACTIVATION, 03 medical and health sciences, Fetus, SDG 3 - Good Health and Well-being, Spheroids, Cellular, medicine, Animals, Progenitor cell, Cancer models, Adaptor Proteins, Signal Transducing, Inflammation, Science & Technology, Biochemistry, Genetics and Molecular Biology(all), INTESTINAL REGENERATION, Epithelial Cells, YAP-Signaling Proteins, General Chemistry, medicine.disease, digestive system diseases, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, Cancer research, Receptors, Transforming Growth Factor beta, Transcription Factors

وصف الملف: application/pdf; Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0a5ec9305d4966a39971a5afa4cf77
https://doi.org/10.1038/s41467-021-23717-5

المؤلفون: Ying Huang, Meng Jiang, Peter S. Dennis, Runsheng Chen, Keith Alder, Yu Xin, Ruben D. Carrasco, Ruiyang Liu, Helen Tanton, Amitabh Srivastava, Mengyun Zhang, Massimo Loda, Tomasz Sewastianik, Yue Kang, Jiao Wang, Ming Liu, Zhongqiu Wang

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Cell biology, Molecular biology, Colorectal cancer, Science, General Physics and Astronomy, Cell Communication, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, BCL9, Cell Line, Tumor, medicine, Animals, Humans, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Cancer, Tumor microenvironment, Multidisciplinary, Oncogene, Wnt signaling pathway, Paraspeckle, General Chemistry, medicine.disease, 3. Good health, Gene Expression Regulation, Neoplastic, Wnt Proteins, 030104 developmental biology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, lcsh:Q, Calcium, Colorectal Neoplasms, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc12fda6f5787a87aac976d30cc8cc0
https://doi.org/10.1038/s41467-019-13842-7

المؤلفون: Fang Yin Lo, Domenico Coppola, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Andrey Loboda, Mingli Yang, Anup Madan, Michael Nebozhyn, Timothy J. Yeatman, Binglin Yue, Jamie K. Teer, Alvaro N.A. Monteiro, Michael J. Schell

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Mutation rate, Colorectal cancer, Science, Adenomatous Polyposis Coli Protein, General Physics and Astronomy, Disease, Kaplan-Meier Estimate, Biology, medicine.disease_cause, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, Article, Statistics, Nonparametric, 03 medical and health sciences, 0302 clinical medicine, Mutation Rate, medicine, Humans, Neoplasm Metastasis, Wnt Signaling Pathway, beta Catenin, Proportional Hazards Models, Cell Nucleus, Multidisciplinary, Staining and Labeling, Proportional hazards model, Cancer, Microsatellite instability, General Chemistry, medicine.disease, Prognosis, 3. Good health, Wnt Proteins, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Cancer research, Microsatellite Instability, KRAS, Colorectal Neoplasms, Genes, Neoplasm

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9179b0d5e6437b95c7fe28841f573a5d
https://doaj.org/article/33d97e94867e429f930222ed4bd1a79a

المؤلفون: Petros Avramopoulos, Andreas-David Brunner, Deepak Ramanujam, Bart De Strooper, Laurenz Grüter, Stefan Engelhardt, Thomas Thum, Norbert Hubner, Regalla Kumarswamy, Yassine Sassi, Xiaoke Yin, Aikaterini S. Papadopoulou, Bernhard Laggerbauer, Stanislas Werfel, Manuel Mayr, Dena Esfandyari, Simon Giosele

المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

مصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, Adult, Male, Science, General Physics and Astronomy, Cardiomegaly, 030204 cardiovascular system & hematology, General Biochemistry, Genetics and Molecular Biology, Article, Muscle hypertrophy, 03 medical and health sciences, Mice, 0302 clinical medicine, Fibrosis, Renal fibrosis, Medicine, Myocyte, Animals, Humans, Myocytes, Cardiac, lcsh:Science, Aged, Pressure overload, Mice, Knockout, Multidisciplinary, business.industry, Myocardium, Cardiac myocyte, Wnt signaling pathway, General Chemistry, Middle Aged, medicine.disease, ddc, Mice, Inbred C57BL, Wnt Proteins, MicroRNAs, 030104 developmental biology, Cardiovascular and Metabolic Diseases, Cancer research, cardiovascular system, lcsh:Q, Female, business, Signal Transduction

وصف الملف: application/pdf; Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ce239aa072baf4c9b9c5481c09717f
https://pubmed.ncbi.nlm.nih.gov/29158499