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المؤلفون: Troy L. Mitchell, Yang Li, Tom Z. Yuan, Meghah Vuppalapaty, Nikita Tripuraneni, Fowler Tristan William, Sung-Jin Lee, Jingjing Ye, Haili Zhang, Erica S. Rego, Hui Chen, Archana Dilip, Liqin Xie, Helene Baribault, Janda Claudia Yvonne, Wen-Chen Yeh, Shengjiang Tu, Maureen Newman, Brian Ouyang, Devin Mutha
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
مصطلحات موضوعية: 0301 basic medicine, Frizzled, Aging, Science, Osteoporosis, Drug Evaluation, Preclinical, General Physics and Astronomy, 030209 endocrinology & metabolism, Regenerative medicine, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, Young Adult, 0302 clinical medicine, In vivo, Bone Density, Medicine, Animals, Humans, Femur, Bone Resorption, Wnt Signaling Pathway, Osteoporosis, Postmenopausal, Aged, Bone mineral, Phenocopy, Multidisciplinary, Bone Density Conservation Agents, Diphosphonates, business.industry, Wnt signaling pathway, Increased Bone Density, Drug Synergism, General Chemistry, medicine.disease, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, Cancer research, Drug Therapy, Combination, Female, business, Femoral Fractures
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المؤلفون: Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom
المساهمون: Center of Experimental and Molecular Medicine, CCA - Cancer biology and immunology, Radiotherapy
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, 12(1):3464. Nature Publishing Group
Nature Communications
S-CORT Consortium 2021, ' Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis ', Nature Communications, vol. 12, 3464 . https://doi.org/10.1038/s41467-021-23717-5مصطلحات موضوعية: 0301 basic medicine, Chemistry(all), MICROSATELLITE INSTABILITY, Carcinogenesis, Colorectal cancer, Cellular differentiation, Receptor, Transforming Growth Factor-beta Type I, General Physics and Astronomy, SESSILE SERRATED ADENOMAS, DISTAL COLON, Kaplan-Meier Estimate, medicine.disease_cause, COLORECTAL-CANCER, 0302 clinical medicine, Transforming Growth Factor beta, Wnt Signaling Pathway, IN-VIVO, Mutation, Multidisciplinary, Cancer stem cells, Wnt signaling pathway, LGR5, Cell Differentiation, Prognosis, Multidisciplinary Sciences, 030220 oncology & carcinogenesis, Colonic Neoplasms, Science & Technology - Other Topics, Stem cell, STEM-CELLS, Signal Transduction, EXPRESSION, Proto-Oncogene Proteins B-raf, Cell Survival, Colon, MAP Kinase Signaling System, Science, INHIBITION, Physics and Astronomy(all), Biology, Article, General Biochemistry, Genetics and Molecular Biology, WNT ACTIVATION, 03 medical and health sciences, Fetus, SDG 3 - Good Health and Well-being, Spheroids, Cellular, medicine, Animals, Progenitor cell, Cancer models, Adaptor Proteins, Signal Transducing, Inflammation, Science & Technology, Biochemistry, Genetics and Molecular Biology(all), INTESTINAL REGENERATION, Epithelial Cells, YAP-Signaling Proteins, General Chemistry, medicine.disease, digestive system diseases, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, Cancer research, Receptors, Transforming Growth Factor beta, Transcription Factors
وصف الملف: application/pdf; Electronic
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المؤلفون: Ying Huang, Meng Jiang, Peter S. Dennis, Runsheng Chen, Keith Alder, Yu Xin, Ruben D. Carrasco, Ruiyang Liu, Helen Tanton, Amitabh Srivastava, Mengyun Zhang, Massimo Loda, Tomasz Sewastianik, Yue Kang, Jiao Wang, Ming Liu, Zhongqiu Wang
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Cell biology, Molecular biology, Colorectal cancer, Science, General Physics and Astronomy, Cell Communication, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, BCL9, Cell Line, Tumor, medicine, Animals, Humans, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Cancer, Tumor microenvironment, Multidisciplinary, Oncogene, Wnt signaling pathway, Paraspeckle, General Chemistry, medicine.disease, 3. Good health, Gene Expression Regulation, Neoplastic, Wnt Proteins, 030104 developmental biology, Tumor progression, 030220 oncology & carcinogenesis, Cancer research, lcsh:Q, Calcium, Colorectal Neoplasms, Protein Binding, Transcription Factors
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المؤلفون: Igor Y. Iskusnykh, Victor V. Chizhikov, Nikolai Fattakhov, Shubha Tole, Achira Roy, Kathleen J. Millen, Ashwin S. Shetty, Ekaterina Y. Steshina, Anne G. Lindgren
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: Male, 0301 basic medicine, Science, Mesenchyme, LIM-Homeodomain Proteins, Neuroepithelial Cells, General Physics and Astronomy, Lissencephaly, Developmental neurogenesis, Neocortex, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mesoderm, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, lcsh:Science, Gyrification, Mice, Knockout, Regulation of gene expression, Multidisciplinary, Wnt signaling pathway, Neural tube, Cell type diversity, Gene Expression Regulation, Developmental, General Chemistry, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Neuroepithelial cell, 030104 developmental biology, medicine.anatomical_structure, Female, lcsh:Q, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors
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المؤلفون: Fang Yin Lo, Domenico Coppola, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Andrey Loboda, Mingli Yang, Anup Madan, Michael Nebozhyn, Timothy J. Yeatman, Binglin Yue, Jamie K. Teer, Alvaro N.A. Monteiro, Michael J. Schell
المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Mutation rate, Colorectal cancer, Science, Adenomatous Polyposis Coli Protein, General Physics and Astronomy, Disease, Kaplan-Meier Estimate, Biology, medicine.disease_cause, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, Article, Statistics, Nonparametric, 03 medical and health sciences, 0302 clinical medicine, Mutation Rate, medicine, Humans, Neoplasm Metastasis, Wnt Signaling Pathway, beta Catenin, Proportional Hazards Models, Cell Nucleus, Multidisciplinary, Staining and Labeling, Proportional hazards model, Cancer, Microsatellite instability, General Chemistry, medicine.disease, Prognosis, 3. Good health, Wnt Proteins, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Cancer research, Microsatellite Instability, KRAS, Colorectal Neoplasms, Genes, Neoplasm
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المؤلفون: Veronique Bataille, Jake Saklatvala, David Baudry, Michael A. Simpson, Richard C. Trembath, Catherine H. Smith, Michael H. Allen, Alexander A. Navarini, Andrew Pink, Johannes Voegel, Sang Hyuck Lee, Christos Petridis, Michael Duckworth, Alison M. Layton, A. David Burden, Isabelle Carlavan, John A. McGrath, Charles Curtis, Tim D. Spector, Jonathan Barker, Nick Dand
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Science, General Physics and Astronomy, Locus (genetics), Genome-wide association study, Disease, Semaphorins, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Acne Vulgaris, Genetic predisposition, medicine, Humans, Genetic Predisposition to Disease, Propionibacterium acnes, lcsh:Science, Acne, Gram-Positive Bacterial Infections, Skin, Multidisciplinary, integumentary system, business.industry, Genetic Variation, Membrane Proteins, General Chemistry, Hair follicle, medicine.disease, Wnt Proteins, 030104 developmental biology, medicine.anatomical_structure, Medical genetics, lcsh:Q, Female, Epidermolysis bullosa, Laminin, business, Hair Follicle, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Petros Avramopoulos, Andreas-David Brunner, Deepak Ramanujam, Bart De Strooper, Laurenz Grüter, Stefan Engelhardt, Thomas Thum, Norbert Hubner, Regalla Kumarswamy, Yassine Sassi, Xiaoke Yin, Aikaterini S. Papadopoulou, Bernhard Laggerbauer, Stanislas Werfel, Manuel Mayr, Dena Esfandyari, Simon Giosele
المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)مصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, Adult, Male, Science, General Physics and Astronomy, Cardiomegaly, 030204 cardiovascular system & hematology, General Biochemistry, Genetics and Molecular Biology, Article, Muscle hypertrophy, 03 medical and health sciences, Mice, 0302 clinical medicine, Fibrosis, Renal fibrosis, Medicine, Myocyte, Animals, Humans, Myocytes, Cardiac, lcsh:Science, Aged, Pressure overload, Mice, Knockout, Multidisciplinary, business.industry, Myocardium, Cardiac myocyte, Wnt signaling pathway, General Chemistry, Middle Aged, medicine.disease, ddc, Mice, Inbred C57BL, Wnt Proteins, MicroRNAs, 030104 developmental biology, Cardiovascular and Metabolic Diseases, Cancer research, cardiovascular system, lcsh:Q, Female, business, Signal Transduction
وصف الملف: application/pdf; Electronic
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المؤلفون: Audrey Bednarczyk, Estelle Woldt, Christine Schaeffer, Rachel L. Matz, Philippe Boucher, Ewa Ninio, Fanny Coudane, Maria Eugenia Chollet, Jérôme Terrand, Daniel Metzger, Walter Wahli, Alain Van Dorsselaer, Véronique Bruban, Pierre Chambon, Danièle Thiersé, Mohamed Mlih, Zeina El Asmar, Sophie Foppolo, Joachim Herz, Christian Boudier
المساهمون: Barthel, Ingrid
المصدر: Nature communications
Nature Communications, vol. 3, no. 1077, pp. 1-10مصطلحات موضوعية: medicine.medical_specialty, Vascular smooth muscle, Immunoblotting, Myocytes, Smooth Muscle, General Physics and Astronomy, 030204 cardiovascular system & hematology, Biology, In Vitro Techniques, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Muscle, Smooth, Vascular, Wnt-5a Protein, Article, Rosiglitazone, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Sciences du Vivant [q-bio]/Biologie cellulaire, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, medicine, Animals, Humans, Immunoprecipitation, Receptor, Vascular Calcification, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, ComputingMilieux_MISCELLANEOUS, In Situ Hybridization, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Multidisciplinary, Membrane Proteins, General Chemistry, medicine.disease, LRP1, Hedgehog signaling pathway, PPAR gamma, Wnt Proteins, Endocrinology, Nuclear receptor, Hormone receptor, LDL receptor, Thiazolidinediones, lipids (amino acids, peptides, and proteins), Low Density Lipoprotein Receptor-Related Protein-1, Calcification
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d1e3a2435513355f01cb21d0559e7a
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