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المؤلفون: Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
المساهمون: Brigham and Women’s Hospital [Boston, MA], Harvard Medical School [Boston] (HMS), Institute of Medical Engineering & Science [Cambridge, MA] (IMES), Massachusetts Institute of Technology (MIT), Broad Institute of MIT and Harvard (BROAD INSTITUTE), Harvard Medical School [Boston] (HMS)-Massachusetts Institute of Technology (MIT)-Massachusetts General Hospital [Boston], Ragon Institute of MGH, MIT and Harvard, Koch Institute for Integrative Cancer Research at MIT [Cambridge, MA], University of Pittsburgh Medical Center [Pittsburgh, PA, États-Unis] (UPMC), Imagerie et Modélisation - Imaging and Modeling, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS), Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Department of Pharmacology, Toxicology, and Therapeutics [Kansas City, KS, USA], University of Kansas Medical Center [Kansas City, KS, USA], Harvard-MIT Division of Health Sciences and Technology [Cambridge], Dana-Farber Cancer Institute [Boston], Harvard Stem Cell Institute [Cambridge, USA] (HSCI), Harvard University, Massachusetts General Hospital [Boston, MA, USA], C..W. is supported by F32DK111151, the Cholangiocarcinoma Foundation Research Fellowship, and the American Liver Foundation Charles Trey, MD Memorial Post-doctoral Research Fellowship. W.G. is supported by R01DK090311, R01DK105198, R24OD017870, and the Claudia Adams Barr Program for Excellence in Cancer Research. W.G. is a Pew Scholar in Biomedical Sciences. A.K.S. was supported, in part, by the Searle Scholars Program, the Beckman Young Investigator Program, a Sloan Fellowship in Chemistry, the NIH (1DP2GM1194192 & RM1HG0061931), and the MIT Stem Cell Initiative through Fondation MIT. U.A. is supported by R01DK098414. S.P.M is supported by NIH/NIDDK P30DK120531, Pittsburgh Liver Research Centre Grant, and NIH/NIDDK (DK62277, DK100287, and CA204586)
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩مصطلحات موضوعية: 0301 basic medicine, MESH: beta Catenin, General Physics and Astronomy, MESH: Cell Cycle, MESH: Mice, Knockout, Biochemistry, Transcriptome, MESH: Hepatocytes, Mice, 0302 clinical medicine, Protein biosynthesis, MESH: Animals, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Mice, Knockout, Multidisciplinary, Fluorescence in situ hybridization, Cell Cycle, MESH: Wnt Signaling Pathway, Wnt signaling pathway, Cell cycle, MESH: Hepatectomy, Liver regeneration, Cell biology, MESH: Wnt Proteins, Liver, 030211 gastroenterology & hepatology, MESH: Liver Regeneration, Reprogramming, Biotechnology, Science, MESH: Acetaminophen, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, MESH: Gene Expression Profiling, MESH: Mice, Inbred C57BL, MESH: Cell Proliferation, Detoxification, Genetics, Animals, Hepatectomy, Transcriptomics, MESH: Mice, Molecular Biology, Acetaminophen, Cell Proliferation, Mechanism (biology), Gene Expression Profiling, Macrophages, MESH: Macrophages, General Chemistry, Regenerative process, Liver Regeneration, Gene expression profiling, Mice, Inbred C57BL, Wnt Proteins, Disease Models, Animal, 030104 developmental biology, Hepatocytes, lcsh:Q, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, Liver function, MESH: Disease Models, Animal, MESH: Liver
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المؤلفون: Hoon Ki Sung, Tae-Hee Kim, Sammy Shun Wai Shi, Lijiang Fei, Noah A. Hahn, Ji-Eun Kim, Wen-Chi Yin, Abilasha Rao-Bhatia, Ju Hee Lee, Xiaoyun Zhang, Chi-chung Hui, Sabrina Coquenlorge, Wasi Rizvi, Kyoung-Han Kim, Guoji Guo
المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Male, Stromal cell, Science, Cell, General Physics and Astronomy, Biology, Zinc Finger Protein Gli2, Ligands, General Biochemistry, Genetics and Molecular Biology, Article, Transcriptome, 03 medical and health sciences, Mice, 0302 clinical medicine, Single-cell analysis, Telocyte, medicine, Animals, Homeostasis, Regeneration, Genetic Testing, Telocytes, Cell Self Renewal, Stem Cell Niche, lcsh:Science, Wnt Signaling Pathway, Mice, Knockout, Multidisciplinary, Wnt signaling pathway, Epithelial Cells, General Chemistry, Cell biology, Gastrointestinal Tract, Wnt Proteins, 030104 developmental biology, medicine.anatomical_structure, lcsh:Q, Pericyte, Stem cell, Stromal Cells, 030217 neurology & neurosurgery, Stem-cell niche
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المؤلفون: Igor Y. Iskusnykh, Victor V. Chizhikov, Nikolai Fattakhov, Shubha Tole, Achira Roy, Kathleen J. Millen, Ashwin S. Shetty, Ekaterina Y. Steshina, Anne G. Lindgren
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: Male, 0301 basic medicine, Science, Mesenchyme, LIM-Homeodomain Proteins, Neuroepithelial Cells, General Physics and Astronomy, Lissencephaly, Developmental neurogenesis, Neocortex, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mesoderm, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, lcsh:Science, Gyrification, Mice, Knockout, Regulation of gene expression, Multidisciplinary, Wnt signaling pathway, Neural tube, Cell type diversity, Gene Expression Regulation, Developmental, General Chemistry, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Neuroepithelial cell, 030104 developmental biology, medicine.anatomical_structure, Female, lcsh:Q, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors
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المؤلفون: Ryan A. Hlady, Katarina Lopusna, Jana Opavska, Peike Sheng, Pawel Nowialis, Olga A. Guryanova, Amarnath Natarajan, Mingyi Xie, Melanie A. Simpson, Alberto Riva, Rene Opavsky, Staci L. Haney, Ajay Abraham
المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, Science, DNMT3B, Embryonic Development, General Physics and Astronomy, Mice, Transgenic, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Animals, Humans, Hedgehog Proteins, DNA (Cytosine-5-)-Methyltransferases, lcsh:Science, Mice, Knockout, Regulation of gene expression, DNA methylation, Multidisciplinary, HEK 293 cells, Wnt signaling pathway, Gene Expression Regulation, Developmental, General Chemistry, Methylation, Hedgehog signaling pathway, Cell biology, Mice, Inbred C57BL, Wnt Proteins, HEK293 Cells, 030104 developmental biology, Embryogenesis, embryonic structures, Biocatalysis, lcsh:Q, Epigenetics, Female, Gene expression, Transcription, 030217 neurology & neurosurgery, Signal Transduction
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المؤلفون: Petros Avramopoulos, Andreas-David Brunner, Deepak Ramanujam, Bart De Strooper, Laurenz Grüter, Stefan Engelhardt, Thomas Thum, Norbert Hubner, Regalla Kumarswamy, Yassine Sassi, Xiaoke Yin, Aikaterini S. Papadopoulou, Bernhard Laggerbauer, Stanislas Werfel, Manuel Mayr, Dena Esfandyari, Simon Giosele
المصدر: Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)مصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, Adult, Male, Science, General Physics and Astronomy, Cardiomegaly, 030204 cardiovascular system & hematology, General Biochemistry, Genetics and Molecular Biology, Article, Muscle hypertrophy, 03 medical and health sciences, Mice, 0302 clinical medicine, Fibrosis, Renal fibrosis, Medicine, Myocyte, Animals, Humans, Myocytes, Cardiac, lcsh:Science, Aged, Pressure overload, Mice, Knockout, Multidisciplinary, business.industry, Myocardium, Cardiac myocyte, Wnt signaling pathway, General Chemistry, Middle Aged, medicine.disease, ddc, Mice, Inbred C57BL, Wnt Proteins, MicroRNAs, 030104 developmental biology, Cardiovascular and Metabolic Diseases, Cancer research, cardiovascular system, lcsh:Q, Female, business, Signal Transduction
وصف الملف: application/pdf; Electronic
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المؤلفون: Audrey Bednarczyk, Estelle Woldt, Christine Schaeffer, Rachel L. Matz, Philippe Boucher, Ewa Ninio, Fanny Coudane, Maria Eugenia Chollet, Jérôme Terrand, Daniel Metzger, Walter Wahli, Alain Van Dorsselaer, Véronique Bruban, Pierre Chambon, Danièle Thiersé, Mohamed Mlih, Zeina El Asmar, Sophie Foppolo, Joachim Herz, Christian Boudier
المساهمون: Barthel, Ingrid
المصدر: Nature communications
Nature Communications, vol. 3, no. 1077, pp. 1-10مصطلحات موضوعية: medicine.medical_specialty, Vascular smooth muscle, Immunoblotting, Myocytes, Smooth Muscle, General Physics and Astronomy, 030204 cardiovascular system & hematology, Biology, In Vitro Techniques, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Muscle, Smooth, Vascular, Wnt-5a Protein, Article, Rosiglitazone, 03 medical and health sciences, Mice, 0302 clinical medicine, Internal medicine, Sciences du Vivant [q-bio]/Biologie cellulaire, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, medicine, Animals, Humans, Immunoprecipitation, Receptor, Vascular Calcification, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, ComputingMilieux_MISCELLANEOUS, In Situ Hybridization, 030304 developmental biology, Mice, Knockout, 0303 health sciences, Multidisciplinary, Membrane Proteins, General Chemistry, medicine.disease, LRP1, Hedgehog signaling pathway, PPAR gamma, Wnt Proteins, Endocrinology, Nuclear receptor, Hormone receptor, LDL receptor, Thiazolidinediones, lipids (amino acids, peptides, and proteins), Low Density Lipoprotein Receptor-Related Protein-1, Calcification
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d1e3a2435513355f01cb21d0559e7a