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المؤلفون: Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom
المساهمون: Center of Experimental and Molecular Medicine, CCA - Cancer biology and immunology, Radiotherapy
المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, 12(1):3464. Nature Publishing Group
Nature Communications
S-CORT Consortium 2021, ' Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis ', Nature Communications, vol. 12, 3464 . https://doi.org/10.1038/s41467-021-23717-5مصطلحات موضوعية: 0301 basic medicine, Chemistry(all), MICROSATELLITE INSTABILITY, Carcinogenesis, Colorectal cancer, Cellular differentiation, Receptor, Transforming Growth Factor-beta Type I, General Physics and Astronomy, SESSILE SERRATED ADENOMAS, DISTAL COLON, Kaplan-Meier Estimate, medicine.disease_cause, COLORECTAL-CANCER, 0302 clinical medicine, Transforming Growth Factor beta, Wnt Signaling Pathway, IN-VIVO, Mutation, Multidisciplinary, Cancer stem cells, Wnt signaling pathway, LGR5, Cell Differentiation, Prognosis, Multidisciplinary Sciences, 030220 oncology & carcinogenesis, Colonic Neoplasms, Science & Technology - Other Topics, Stem cell, STEM-CELLS, Signal Transduction, EXPRESSION, Proto-Oncogene Proteins B-raf, Cell Survival, Colon, MAP Kinase Signaling System, Science, INHIBITION, Physics and Astronomy(all), Biology, Article, General Biochemistry, Genetics and Molecular Biology, WNT ACTIVATION, 03 medical and health sciences, Fetus, SDG 3 - Good Health and Well-being, Spheroids, Cellular, medicine, Animals, Progenitor cell, Cancer models, Adaptor Proteins, Signal Transducing, Inflammation, Science & Technology, Biochemistry, Genetics and Molecular Biology(all), INTESTINAL REGENERATION, Epithelial Cells, YAP-Signaling Proteins, General Chemistry, medicine.disease, digestive system diseases, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, Cancer research, Receptors, Transforming Growth Factor beta, Transcription Factors
وصف الملف: application/pdf; Electronic
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المؤلفون: Virginie Lecaudey, Hiroyuki Nakajima, Wiebke Herzog, Peng Xia, Naoki Mochizuki, Dorothee Bornhorst, Carl-Philipp Heisenberg, Salim Abdelilah-Seyfried, Deborah Yelon, Chaitanya Dingare
المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)مصطلحات موضوعية: 0301 basic medicine, General Physics and Astronomy, Extracellular matrix, 0302 clinical medicine, Transcriptional regulation, Morphogenesis, lcsh:Science, Zebrafish, YAP1, Multidisciplinary, Cadherins, Cell biology, Biomechanical Phenomena, Intercellular Junctions, cardiovascular system, Homeobox Protein Nkx-2.5, Signal transduction, Signal Transduction, animal structures, Science, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antigens, CD, ddc:570, Animals, cardiovascular diseases, Heart Atria, Endocardium, Institut für Biochemie und Biologie, Cell Proliferation, Cell Size, Cell Nucleus, Hippo signaling pathway, Cell growth, Myocardium, fungi, YAP-Signaling Proteins, General Chemistry, Zebrafish Proteins, biology.organism_classification, Wnt Proteins, Cytoskeletal Proteins, 030104 developmental biology, Mutation, Trans-Activators, lcsh:Q, 030217 neurology & neurosurgery
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المؤلفون: Zhigang Xu, Ji-Tong Li, De-Li Shi, Xiao-Ning Cheng, Ming Shao, Jing Qi, Yanfei Wang
المساهمون: Shandong University, Laboratoire de Biologie du Développement [IBPS] (LBD), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Shi, De-Li
المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications, 2017, 8 (1), pp.1353. ⟨10.1038/s41467-017-01552-x⟩مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Embryo, Nonmammalian, Centriole, MAP Kinase Kinase 4, Xenopus, [SDV]Life Sciences [q-bio], Dishevelled Proteins, General Physics and Astronomy, 0302 clinical medicine, Cell Movement, Cell polarity, lcsh:Science, Zebrafish, chemistry.chemical_classification, Multidisciplinary, biology, Wnt signaling pathway, Cell Polarity, Gene Expression Regulation, Developmental, Anatomy, Dishevelled, Cell biology, [SDV] Life Sciences [q-bio], embryonic structures, Female, Signal Transduction, animal structures, Science, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, AXIN1, Animals, Humans, Adaptor Proteins, Signal Transducing, Membrane Proteins, Gastrula, General Chemistry, Zebrafish Proteins, biology.organism_classification, Wnt Proteins, Gastrulation, 030104 developmental biology, chemistry, Mutation, lcsh:Q, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Fang Yin Lo, Domenico Coppola, Gabriel A. Bien-Willner, Danielle M. Greenawalt, Andrey Loboda, Mingli Yang, Anup Madan, Michael Nebozhyn, Timothy J. Yeatman, Binglin Yue, Jamie K. Teer, Alvaro N.A. Monteiro, Michael J. Schell
المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communicationsمصطلحات موضوعية: 0301 basic medicine, Mutation rate, Colorectal cancer, Science, Adenomatous Polyposis Coli Protein, General Physics and Astronomy, Disease, Kaplan-Meier Estimate, Biology, medicine.disease_cause, Bioinformatics, General Biochemistry, Genetics and Molecular Biology, Article, Statistics, Nonparametric, 03 medical and health sciences, 0302 clinical medicine, Mutation Rate, medicine, Humans, Neoplasm Metastasis, Wnt Signaling Pathway, beta Catenin, Proportional Hazards Models, Cell Nucleus, Multidisciplinary, Staining and Labeling, Proportional hazards model, Cancer, Microsatellite instability, General Chemistry, medicine.disease, Prognosis, 3. Good health, Wnt Proteins, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation (genetic algorithm), Mutation, Cancer research, Microsatellite Instability, KRAS, Colorectal Neoplasms, Genes, Neoplasm