المؤلفون: Joshua D. G. Leach, Nikola Vlahov, Petros Tsantoulis, Rachel A. Ridgway, Dustin J. Flanagan, Kathryn Gilroy, Nathalie Sphyris, Ester G. Vázquez, David F. Vincent, William J. Faller, Michael C. Hodder, Alexander Raven, Sigrid Fey, Arafath K. Najumudeen, Douglas Strathdee, Colin Nixon, Mark Hughes, William Clark, Robin Shaw, S:CORT consortium, Sander R. van Hooff, David J. Huels, Jan Paul Medema, Simon T. Barry, Margaret C. Frame, Asier Unciti-Broceta, Simon J. Leedham, Gareth J. Inman, Rene Jackstadt, Barry J. Thompson, Andrew D. Campbell, Sabine Tejpar, Owen J. Sansom

المساهمون: Center of Experimental and Molecular Medicine, CCA - Cancer biology and immunology, Radiotherapy

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature communications, 12(1):3464. Nature Publishing Group
Nature Communications
S-CORT Consortium 2021, ' Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis ', Nature Communications, vol. 12, 3464 . https://doi.org/10.1038/s41467-021-23717-5

مصطلحات موضوعية: 0301 basic medicine, Chemistry(all), MICROSATELLITE INSTABILITY, Carcinogenesis, Colorectal cancer, Cellular differentiation, Receptor, Transforming Growth Factor-beta Type I, General Physics and Astronomy, SESSILE SERRATED ADENOMAS, DISTAL COLON, Kaplan-Meier Estimate, medicine.disease_cause, COLORECTAL-CANCER, 0302 clinical medicine, Transforming Growth Factor beta, Wnt Signaling Pathway, IN-VIVO, Mutation, Multidisciplinary, Cancer stem cells, Wnt signaling pathway, LGR5, Cell Differentiation, Prognosis, Multidisciplinary Sciences, 030220 oncology & carcinogenesis, Colonic Neoplasms, Science & Technology - Other Topics, Stem cell, STEM-CELLS, Signal Transduction, EXPRESSION, Proto-Oncogene Proteins B-raf, Cell Survival, Colon, MAP Kinase Signaling System, Science, INHIBITION, Physics and Astronomy(all), Biology, Article, General Biochemistry, Genetics and Molecular Biology, WNT ACTIVATION, 03 medical and health sciences, Fetus, SDG 3 - Good Health and Well-being, Spheroids, Cellular, medicine, Animals, Progenitor cell, Cancer models, Adaptor Proteins, Signal Transducing, Inflammation, Science & Technology, Biochemistry, Genetics and Molecular Biology(all), INTESTINAL REGENERATION, Epithelial Cells, YAP-Signaling Proteins, General Chemistry, medicine.disease, digestive system diseases, Mice, Inbred C57BL, Wnt Proteins, 030104 developmental biology, Cancer research, Receptors, Transforming Growth Factor beta, Transcription Factors

وصف الملف: application/pdf; Electronic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0a5ec9305d4966a39971a5afa4cf77
https://doi.org/10.1038/s41467-021-23717-5

المؤلفون: Sophie Balmer, Marek Mlodzik, Davide Esposito, Carlo Iomini, Stuart A. Aaronson, Linh T. Vuong

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Science, Mutant, Active Transport, Cell Nucleus, Kinesins, General Physics and Astronomy, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Mediator, Microtubule, Animals, Drosophila Proteins, Wings, Animal, RNA, Small Interfering, lcsh:Science, Wnt Signaling Pathway, beta Catenin, Armadillo Domain Proteins, Cell Nucleus, Multidisciplinary, Chemistry, Wnt signaling pathway, General Chemistry, Cell biology, Wnt Proteins, Protein Transport, 030104 developmental biology, Cytoplasm, Catenin, Kinesin, Drosophila, RNA Interference, lcsh:Q, sense organs, Carrier Proteins, 030217 neurology & neurosurgery, Nuclear localization sequence, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a77d88fd8afdbd292a669b9771f29d
http://link.springer.com/article/10.1038/s41467-018-07605-z

المؤلفون: Andrey Glinka, Hyeyoon Lee, Rui Sun, Carina Seidl, Christof Niehrs

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: 0301 basic medicine, animal structures, Science, Ubiquitin-Protein Ligases, Xenopus, Embryonic Development, General Physics and Astronomy, Bone Morphogenetic Protein 4, Xenopus Proteins, Ligands, Article, General Biochemistry, Genetics and Molecular Biology, Xenopus laevis, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Cell Line, Tumor, Membrane proteins, Developmental biology, Animals, Humans, lcsh:Science, Receptor, RSPO2, Bone Morphogenetic Protein Receptors, Type I, In Situ Hybridization, Tissue homeostasis, Multidisciplinary, biology, Chemistry, Synexpression, Wnt signaling pathway, Gene Expression Regulation, Developmental, General Chemistry, biology.organism_classification, BMPR1A, Cell biology, Wnt Proteins, 030104 developmental biology, embryonic structures, Intercellular Signaling Peptides and Proteins, lcsh:Q, Stem cell, Thrombospondins, 030217 neurology & neurosurgery, Signal Transduction, Cell signalling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970268727c5fdf4537b4e06bdc1f6e98
https://doi.org/10.1038/s41467-020-19373-w

المؤلفون: Igor Y. Iskusnykh, Victor V. Chizhikov, Nikolai Fattakhov, Shubha Tole, Achira Roy, Kathleen J. Millen, Ashwin S. Shetty, Ekaterina Y. Steshina, Anne G. Lindgren

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications

مصطلحات موضوعية: Male, 0301 basic medicine, Science, Mesenchyme, LIM-Homeodomain Proteins, Neuroepithelial Cells, General Physics and Astronomy, Lissencephaly, Developmental neurogenesis, Neocortex, Biology, Article, General Biochemistry, Genetics and Molecular Biology, Mesoderm, Mice, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, lcsh:Science, Gyrification, Mice, Knockout, Regulation of gene expression, Multidisciplinary, Wnt signaling pathway, Neural tube, Cell type diversity, Gene Expression Regulation, Developmental, General Chemistry, medicine.disease, Mice, Inbred C57BL, Wnt Proteins, Neuroepithelial cell, 030104 developmental biology, medicine.anatomical_structure, Female, lcsh:Q, Neuroscience, 030217 neurology & neurosurgery, Signal Transduction, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::525c0e26c1a722217656ebbd6878efaa
https://doi.org/10.1038/s41467-019-12913-z

المؤلفون: Ryan A. Hlady, Katarina Lopusna, Jana Opavska, Peike Sheng, Pawel Nowialis, Olga A. Guryanova, Amarnath Natarajan, Mingyi Xie, Melanie A. Simpson, Alberto Riva, Rene Opavsky, Staci L. Haney, Ajay Abraham

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)

مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, Science, DNMT3B, Embryonic Development, General Physics and Astronomy, Mice, Transgenic, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Animals, Humans, Hedgehog Proteins, DNA (Cytosine-5-)-Methyltransferases, lcsh:Science, Mice, Knockout, Regulation of gene expression, DNA methylation, Multidisciplinary, HEK 293 cells, Wnt signaling pathway, Gene Expression Regulation, Developmental, General Chemistry, Methylation, Hedgehog signaling pathway, Cell biology, Mice, Inbred C57BL, Wnt Proteins, HEK293 Cells, 030104 developmental biology, Embryogenesis, embryonic structures, Biocatalysis, lcsh:Q, Epigenetics, Female, Gene expression, Transcription, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba9b8b2e14926e9e1c8d9259b616aab3
https://doi.org/10.1038/s41467-019-12355-7

المؤلفون: Dominic B. Bernkopf, Martina Brückner, Jürgen Behrens, Michel V. Hadjihannas

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Cell biology, Science, General Physics and Astronomy, macromolecular substances, Article, General Biochemistry, Genetics and Molecular Biology, Gene Knockout Techniques, 03 medical and health sciences, 0302 clinical medicine, Axin Protein, Transcription (biology), Cell Line, Tumor, AXIN2, Humans, lcsh:Science, Wnt Signaling Pathway, Transcription factor, beta Catenin, Cancer, Cell Proliferation, Multidisciplinary, Drug discovery, Chemistry, HEK 293 cells, technology, industry, and agriculture, Wnt signaling pathway, General Chemistry, Wnt Proteins, HEK293 Cells, 030104 developmental biology, lcsh:Q, CRISPR-Cas Systems, Signal transduction, Colorectal Neoplasms, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09981b25d687f3e442034d92a1dfaa76
https://doi.org/10.1038/s41467-019-12203-8

المؤلفون: Virginie Lecaudey, Hiroyuki Nakajima, Wiebke Herzog, Peng Xia, Naoki Mochizuki, Dorothee Bornhorst, Carl-Philipp Heisenberg, Salim Abdelilah-Seyfried, Deborah Yelon, Chaitanya Dingare

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: 0301 basic medicine, General Physics and Astronomy, Extracellular matrix, 0302 clinical medicine, Transcriptional regulation, Morphogenesis, lcsh:Science, Zebrafish, YAP1, Multidisciplinary, Cadherins, Cell biology, Biomechanical Phenomena, Intercellular Junctions, cardiovascular system, Homeobox Protein Nkx-2.5, Signal transduction, Signal Transduction, animal structures, Science, Biology, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Antigens, CD, ddc:570, Animals, cardiovascular diseases, Heart Atria, Endocardium, Institut für Biochemie und Biologie, Cell Proliferation, Cell Size, Cell Nucleus, Hippo signaling pathway, Cell growth, Myocardium, fungi, YAP-Signaling Proteins, General Chemistry, Zebrafish Proteins, biology.organism_classification, Wnt Proteins, Cytoskeletal Proteins, 030104 developmental biology, Mutation, Trans-Activators, lcsh:Q, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473521eb68e1a8ad6f6d969e20014647
http://europepmc.org/articles/PMC6739419

المؤلفون: Timothy Q. DuBuc, Thomas B. Stephenson, Amber N. Rock, Mark Q. Martindale

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, food.ingredient, animal structures, Science, General Physics and Astronomy, nematostella-vectensis, Nematostella, ctenophore mnemiopsis-leidyi, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, food, evolution, Animals, hydra, animal-vegetal axis, Hox gene, genome, Bilateria, Body Patterning, Multidisciplinary, Gastrulation, Genes, Homeobox, Wnt signaling pathway, Gene Expression Regulation, Developmental, Starlet sea anemone, sea-anemone, homeobox genes, General Chemistry, Blastula, biology.organism_classification, Wnt Proteins, Sea Anemones, 030104 developmental biology, fate, Evolutionary biology, embryonic structures, oral-aboral axis, Homeobox, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f043a76456c11657c829ef20fdcd526
https://doaj.org/article/822e9a3de54442eeb8f16a20846fe809

المؤلفون: Zhigang Xu, Ji-Tong Li, De-Li Shi, Xiao-Ning Cheng, Ming Shao, Jing Qi, Yanfei Wang

المساهمون: Shandong University, Laboratoire de Biologie du Développement [IBPS] (LBD), Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Paris Seine (IBPS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Shi, De-Li

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Nature Communications
Nature Communications, 2017, 8 (1), pp.1353. ⟨10.1038/s41467-017-01552-x⟩

مصطلحات موضوعية: 0301 basic medicine, Scaffold protein, Embryo, Nonmammalian, Centriole, MAP Kinase Kinase 4, Xenopus, [SDV]Life Sciences [q-bio], Dishevelled Proteins, General Physics and Astronomy, 0302 clinical medicine, Cell Movement, Cell polarity, lcsh:Science, Zebrafish, chemistry.chemical_classification, Multidisciplinary, biology, Wnt signaling pathway, Cell Polarity, Gene Expression Regulation, Developmental, Anatomy, Dishevelled, Cell biology, [SDV] Life Sciences [q-bio], embryonic structures, Female, Signal Transduction, animal structures, Science, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, AXIN1, Animals, Humans, Adaptor Proteins, Signal Transducing, Membrane Proteins, Gastrula, General Chemistry, Zebrafish Proteins, biology.organism_classification, Wnt Proteins, Gastrulation, 030104 developmental biology, chemistry, Mutation, lcsh:Q, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7f9f29eb55377fa8f1f22b7d8ee21e
http://link.springer.com/article/10.1038/s41467-017-01552-x

المؤلفون: Oscar E. Ruiz, Elizabeth A. Sumner, Courtney K. Brock, Stephen T. Wallin, Amrita Mandal, George T. Eisenhoffer, Krystin M. Samms

المصدر: Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Programmed cell death, Cell signaling, Embryo, Nonmammalian, Cell division, Science, Cell, General Physics and Astronomy, Apoptosis, Biology, Epithelium, Article, General Biochemistry, Genetics and Molecular Biology, Extracellular Vesicles, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, ortho-Aminobenzoates, lcsh:Science, Zebrafish, Tissue homeostasis, Cell Proliferation, 030304 developmental biology, 0303 health sciences, Multidisciplinary, Phenylurea Compounds, Stem Cells, Wnt signaling pathway, Epithelial Cells, General Chemistry, Zebrafish Proteins, Cell biology, Wnt Proteins, Cytoskeletal Proteins, medicine.anatomical_structure, Caspases, 030220 oncology & carcinogenesis, lcsh:Q, Stem cell, Cell Division, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c2356028c041cd5d95ac34152ef29f
https://doi.org/10.1038/s41467-019-09010-6