المؤلفون: Oh S; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea., Yeom J; Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea.; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Korea.; Convergence Medicine Research Center, Asan Institute for Life Sciences, Seoul, Korea., Cho HJ; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.; Precision Medicine Research Institute, Samsung Medical Center, Seoul, Korea., Kim JH; Graduate Program for Nanomedical Science, Yonsei University, Seoul, Korea., Yoon SJ; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.; Department of Biochemistry and Molecular Biology, Yonsei University College of Medicine, Seoul, Korea., Kim H; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea., Sa JK; Department of Biomedical Sciences, Korea University College of Medicine, Seoul, Korea., Ju S; Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea.; Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul, Korea., Lee H; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea.; Department of Systems Biology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea., Oh MJ; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea., Lee W; Department of Computer Science, Hanyang University, Seoul, Korea., Kwon Y; Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea.; Department of Life Science and Research Institute for Natural Sciences, Hanyang University, Seoul, Korea., Li H; Department of Computer Science, Hanyang University, Seoul, Korea.; School of Computer Science and Engineering, Soongsil University, Seoul, Korea., Choi S; Department of Computer Science, Hanyang University, Seoul, Korea., Han JH; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea.; Department of Medical Science, Yonsei University Graduate School, Seoul, Korea., Chang JH; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea., Choi E; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea., Kim J; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea.; Precision Medicine Research Institute, Samsung Medical Center, Seoul, Korea., Her NG; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea., Kim SH; Department of Pathology, Yonsei University College of Medicine, Seoul, Korea., Kang SG; Department of Medical Science, Yonsei University Graduate School, Seoul, Korea.; Department of Neurosurgery, Brain Tumor Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea., Paek E; Department of Computer Science, Hanyang University, Seoul, Korea. eunokpaek@hanyang.ac.kr., Nam DH; Institute for Refractory Cancer Research, Samsung Medical Center, Seoul, Korea. nsnam@skku.edu.; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. nsnam@skku.edu.; Department of Health Sciences and Technology, SAIHST, Sungkyunkwan University, Seoul, Korea. nsnam@skku.edu., Lee C; Center for Theragnosis, Korea Institute of Science and Technology, Seoul, Korea. clee270@kist.re.kr.; Division of Bio-Medical Science & Technology, KIST School, Korea University of Science and Technology, Seoul, Korea. clee270@kist.re.kr.; Department of Converging Science and Technology, KHU-KIST, Kyung Hee University, Seoul, Korea. clee270@kist.re.kr., Kim HS; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea. hsfkim@yuhs.ac.; Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea. hsfkim@yuhs.ac.

المصدر: Nature communications [Nat Commun] 2020 Jul 03; Vol. 11 (1), pp. 3288. Date of Electronic Publication: 2020 Jul 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor/*metabolism , Brain Neoplasms/*metabolism , Glioblastoma/*metabolism , Isocitrate Dehydrogenase/*genetics , Proteogenomics/*methods , Proteomics/*methods, Benzamides/pharmacology ; Biomarkers, Tumor/genetics ; Brain Neoplasms/genetics ; Brain Neoplasms/therapy ; Cell Line, Tumor ; Cell Survival/drug effects ; Cell Survival/genetics ; Glioblastoma/genetics ; Glioblastoma/therapy ; Humans ; Isocitrate Dehydrogenase/classification ; Isocitrate Dehydrogenase/metabolism ; Kaplan-Meier Estimate ; Mechanistic Target of Rapamycin Complex 1/antagonists & inhibitors ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Mechanistic Target of Rapamycin Complex 2/antagonists & inhibitors ; Mechanistic Target of Rapamycin Complex 2/metabolism ; Morpholines/pharmacology ; Mutation ; Prognosis ; Protein Kinase Inhibitors/pharmacology ; Pyrimidines/pharmacology

المؤلفون: Se Hoon Kim, Wonyeop Lee, Honglan Li, Jason K. Sa, Hyun Seok Kim, Seunghyuk Choi, Jayeon Kim, Yumi Kwon, Oh Sejin, Ju Hwa Kim, Nam Gu Her, Jang Hee Han, Shinyeong Ju, Hwanho Lee, Cheolju Lee, Eunok Paek, Eunsuk Choi, Jeonghun Yeom, Myung Joon Oh, Do-Hyun Nam, Hee Jin Cho, Hakhyun Kim, Jong Hee Chang, Seon Jin Yoon, Seok Gu Kang

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Cell Survival, Science, Morpholines, General Physics and Astronomy, Proteomic analysis, mTORC1, Kaplan-Meier Estimate, Mechanistic Target of Rapamycin Complex 2, Biology, Mechanistic Target of Rapamycin Complex 1, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, 0302 clinical medicine, Glioma, Cell Line, Tumor, medicine, Biomarkers, Tumor, Humans, Phosphoglycerate dehydrogenase, lcsh:Science, neoplasms, Protein Kinase Inhibitors, Proteogenomics, Multidisciplinary, Brain Neoplasms, Wild type, General Chemistry, medicine.disease, Prognosis, Immune checkpoint, Isocitrate Dehydrogenase, nervous system diseases, CNS cancer, 030104 developmental biology, Isocitrate dehydrogenase, FKBP, Pyrimidines, 030220 oncology & carcinogenesis, Benzamides, Mutation, Cancer research, lcsh:Q, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e882ba4c93bcaca33a47d1e76ca4db
http://europepmc.org/articles/PMC7335111