المؤلفون: Freckmann EC; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Sandilands E; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Cumming E; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Neilson M; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Román-Fernández A; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Nikolatou K; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Nacke M; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Lannagan TRM; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Hedley A; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Strachan D; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Salji M; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Morton JP; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., McGarry L; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Leung HY; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Sansom OJ; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Miller CJ; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom., Bryant DM; Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1HQ, United Kingdom. david.bryant@glasgow.ac.uk.; The CRUK Beatson Institute, Glasgow, G61 1BD, United Kingdom. david.bryant@glasgow.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Sep 09; Vol. 13 (1), pp. 5317. Date of Electronic Publication: 2022 Sep 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/diagnostic imaging , Proteomics*, Diagnostic Imaging ; Humans ; Phenotype

المؤلفون: Nacke M; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Sandilands E; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Nikolatou K; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Román-Fernández Á; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Mason S; The CRUK Beatson Institute, Glasgow, UK., Patel R; The CRUK Beatson Institute, Glasgow, UK., Lilla S; The CRUK Beatson Institute, Glasgow, UK., Yelland T; The CRUK Beatson Institute, Glasgow, UK., Galbraith LCA; The CRUK Beatson Institute, Glasgow, UK., Freckmann EC; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., McGarry L; The CRUK Beatson Institute, Glasgow, UK., Morton JP; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Shanks E; The CRUK Beatson Institute, Glasgow, UK., Leung HY; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Markert E; The CRUK Beatson Institute, Glasgow, UK., Ismail S; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK.; Department of Chemistry, KU Leuven, Celestijnenlaan, Belgium., Zanivan S; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Blyth K; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.; The CRUK Beatson Institute, Glasgow, UK., Bryant DM; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK. david.bryant@glasgow.ac.uk.; The CRUK Beatson Institute, Glasgow, UK. david.bryant@glasgow.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 Mar 12; Vol. 12 (1), pp. 1623. Date of Electronic Publication: 2021 Mar 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasm Metastasis*/genetics , Signal Transduction*, Guanine Nucleotide Exchange Factors/*metabolism , Phosphatidylinositols/*metabolism, ADP-Ribosylation Factor 6 ; ADP-Ribosylation Factors/metabolism ; Animals ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Cell Line, Tumor ; Guanine Nucleotide Exchange Factors/genetics ; Heterografts ; Humans ; Low Density Lipoprotein Receptor-Related Protein-1/metabolism ; Male ; Mice ; Mice, Nude ; Neoplasms/metabolism ; Proto-Oncogene Proteins c-akt/metabolism

المؤلفون: Blomme A; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Ford CA; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Mui E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Patel R; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Ntala C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Jamieson LE; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., Planque M; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium., McGregor GH; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Peixoto P; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, 25000, Besançon, France.; EPIGENExp (EPIgenetics and GENe EXPression Technical Platform), Besançon, France.; DIMACELL Dispositif Interrégional d'Imagerie Cellulaire, Dijon, France., Hervouet E; Univ. Bourgogne Franche-Comté, INSERM, EFS BFC, UMR1098, Interactions Hôte-Greffon-Tumeur/Ingénierie Cellulaire et Génique, 25000, Besançon, France.; EPIGENExp (EPIgenetics and GENe EXPression Technical Platform), Besançon, France.; DIMACELL Dispositif Interrégional d'Imagerie Cellulaire, Dijon, France., Nixon C; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Salji M; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Gaughan L; Northern Institute for Cancer Research, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK., Markert E; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Repiscak P; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Sumpton D; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Blanco GR; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Lilla S; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Kamphorst JJ; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Graham D; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., Faulds K; Centre for Molecular Nanometrology, Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK., MacKay GM; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK., Fendt SM; Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, 3000, Leuven, Belgium.; Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Herestraat 49, 3000, Leuven, Belgium., Zanivan S; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Leung HY; CRUK Beatson Institute, Garscube Estate, Switchback Road, Glasgow, G61 1BD, UK. h.leung@beatson.gla.ac.uk.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK. h.leung@beatson.gla.ac.uk.

المصدر: Nature communications [Nat Commun] 2020 May 19; Vol. 11 (1), pp. 2508. Date of Electronic Publication: 2020 May 19.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Lipid Metabolism*, Oxidoreductases Acting on CH-CH Group Donors/*metabolism , Prostatic Neoplasms, Castration-Resistant/*enzymology, Androgen Receptor Antagonists/administration & dosage ; Disease Progression ; Homeostasis ; Humans ; Male ; Mitochondria/enzymology ; Mitochondria/genetics ; Oxidoreductases Acting on CH-CH Group Donors/genetics ; Phospholipids/metabolism ; Prostate/enzymology ; Prostate/metabolism ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/genetics ; Receptors, Androgen/genetics ; Receptors, Androgen/metabolism