المؤلفون: Yang X; Yan'an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, 650051, China.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Kunming, Yunnan, 650051, China.; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Xu H; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Yang X; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Wang H; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Zou L; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Yang Q; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Qi X; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China., Li L; Research Center of Stem cells and Ageing, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, China., Duan H; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100000, China., Yan X; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100000, China., Fu NY; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; ACRF Cancer Biology and Stem Cells Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia., Tan J; Yan'an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, 650051, China. kmtjing@sina.com.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Kunming, Yunnan, 650051, China. kmtjing@sina.com., Hou Z; Yan'an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan, 650051, China. HZL579@163.com.; Key Laboratory of Tumor Immunological Prevention and Treatment of Yunnan Province, Kunming, Yunnan, 650051, China. HZL579@163.com., Jiao B; Key Laboratory of Genetic Evolution & Animal Models (Chinese Academy of Sciences), Chinese Academy of Sciences, Kunming, Yunnan, 650201, China. jiaobaowei@mail.kiz.ac.cn.; KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, 650201, China. jiaobaowei@mail.kiz.ac.cn.

المصدر: Nature communications [Nat Commun] 2024 Jan 02; Vol. 15 (1), pp. 36. Date of Electronic Publication: 2024 Jan 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Wnt Proteins*/genetics , Wnt Proteins*/metabolism , Wnt Signaling Pathway*, Mice ; Animals ; Wnt-5a Protein/genetics ; Wnt-5a Protein/metabolism ; Cell Differentiation ; Morphogenesis ; Mice, Knockout ; Macrophages/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism

المؤلفون: Peysson A; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Zariohi N; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Gendrel M; Institut de Biologie de l'Ecole Normale Supérieure (IBENS), Ecole Normale Supérieure, CNRS, INSERM, Université Paris Sciences et Lettres Research University, Paris, 75005, France., Chambert-Loir A; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Frébault N; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Cheynet E; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Andrini O; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France., Boulin T; Université Claude Bernard Lyon 1, CNRS UMR 5284, INSERM U1314, MeLiS, Lyon, 69008, France. thomas.boulin@univ-lyon1.fr.

المصدر: Nature communications [Nat Commun] 2024 Jun 10; Vol. 15 (1), pp. 4935. Date of Electronic Publication: 2024 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Caenorhabditis elegans*/metabolism , Caenorhabditis elegans Proteins*/metabolism , Caenorhabditis elegans Proteins*/genetics , Cell Polarity* , Dystrophin*/metabolism , Dystrophin*/genetics , Wnt Signaling Pathway* , Muscles*/metabolism, Animals ; Dishevelled Proteins/metabolism ; Dishevelled Proteins/genetics ; Receptor Tyrosine Kinase-like Orphan Receptors/metabolism ; Receptor Tyrosine Kinase-like Orphan Receptors/genetics ; Cell Membrane/metabolism ; Dystrophin-Associated Protein Complex/metabolism ; Dystrophin-Associated Protein Complex/genetics ; Wnt Proteins/metabolism ; Signal Transduction

المؤلفون: Chang CH; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Liu F; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Militi S; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Hester S; Target Discovery Institute, Nuffield Department of Medicine, Old Road, University of Oxford, Oxford, OX3 7FZ, UK., Nibhani R; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Deng S; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Dunford J; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Rendek A; Department of Histopathology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Soonawalla Z; Department of Hepatobiliary and Pancreatic Surgery, Oxford University Hospitals NHS, Oxford, UK., Fischer R; Target Discovery Institute, Nuffield Department of Medicine, Old Road, University of Oxford, Oxford, OX3 7FZ, UK., Oppermann U; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK., Pauklin S; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Old Road, Oxford, OX3 7LD, UK. siim.pauklin@ndorms.ox.ac.uk.

المصدر: Nature communications [Nat Commun] 2024 Apr 27; Vol. 15 (1), pp. 3580. Date of Electronic Publication: 2024 Apr 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplastic Stem Cells*/metabolism , Neoplastic Stem Cells*/pathology , Paracrine Communication* , E2F1 Transcription Factor*/metabolism , E2F1 Transcription Factor*/genetics , Pancreatic Neoplasms*/metabolism , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/genetics , E2F4 Transcription Factor*/metabolism , E2F4 Transcription Factor*/genetics, Humans ; Cell Line, Tumor ; Animals ; Carcinoma, Pancreatic Ductal/pathology ; Carcinoma, Pancreatic Ductal/genetics ; Carcinoma, Pancreatic Ductal/metabolism ; Wnt Proteins/metabolism ; Wnt Proteins/genetics ; Retinoblastoma Protein/metabolism ; Retinoblastoma Protein/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; p300-CBP Transcription Factors/metabolism ; p300-CBP Transcription Factors/genetics ; Gene Expression Regulation, Neoplastic ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Female ; Cell Proliferation ; Mice ; Signal Transduction ; Drug Resistance, Neoplasm/genetics

المؤلفون: Hu DJ; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Yun J; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Elstrott J; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA., Jasper H; Genentech Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. jasperh@gene.com.

المصدر: Nature communications [Nat Commun] 2021 Dec 09; Vol. 12 (1), pp. 7150. Date of Electronic Publication: 2021 Dec 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cell Movement*, Drosophila/*metabolism , Enteroendocrine Cells/*cytology , Intestinal Mucosa/*cytology , Stem Cells/*cytology , Wnt Proteins/*metabolism , Wounds and Injuries/*physiopathology, Animals ; Drosophila/cytology ; Drosophila/genetics ; Drosophila Proteins/genetics ; Drosophila Proteins/metabolism ; Intestinal Mucosa/metabolism ; Intestines ; Receptor Protein-Tyrosine Kinases/genetics ; Receptor Protein-Tyrosine Kinases/metabolism ; Stem Cells/metabolism ; Wnt Proteins/genetics ; Wnt Signaling Pathway ; Wounds and Injuries/genetics ; Wounds and Injuries/metabolism

المؤلفون: Manoranjan B; Section of Neurosurgery, Department of Clinical Neurosciences, University of Calgary, Calgary, AB, T2N 1N4, Canada.; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Venugopal C; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Bakhshinyan D; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Adile AA; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Richards L; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Kameda-Smith MM; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Whitley O; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Department of Computer Science, University of Toronto, Toronto, ON, M5S 1A8, Canada., Dvorkin-Gheva A; Department of Pathology, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Subapanditha M; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada., Savage N; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada., Tatari N; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada., McKenna D; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Bassey-Archibong B; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada., Winegarden N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Hallett R; Northern Biologics, Toronto, ON, M5G 1L7, Canada., Provias JP; Department of Pathology, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Yarascavitch B; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Ajani O; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Fleming A; Department of Pediatrics, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada., Bader GD; Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada.; Department of Computer Science, University of Toronto, Toronto, ON, M5S 1A8, Canada.; The Donnelly Centre, University of Toronto, Toronto, ON, M5S 3E1, Canada., Pugh TJ; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, M5G 2M9, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5S 1A8, Canada., Doble BW; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada.; Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada.; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, MB, R3E 0W2, Canada., Singh SK; McMaster Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON, L8S 4K1, Canada. ssingh@mcmaster.ca.; Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada. ssingh@mcmaster.ca.; Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, ON, L8N 3Z5, Canada. ssingh@mcmaster.ca.

المصدر: Nature communications [Nat Commun] 2020 Aug 28; Vol. 11 (1), pp. 4323. Date of Electronic Publication: 2020 Aug 28.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cerebellar Neoplasms/*therapy , Medulloblastoma/*therapy , Wnt Proteins/*pharmacology , Wnt Proteins/*therapeutic use, Animals ; Carcinogenesis ; Cell Line, Tumor ; Cell Proliferation ; Cerebellar Neoplasms/pathology ; Disease Models, Animal ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic ; Heterografts ; Humans ; Medulloblastoma/genetics ; Medulloblastoma/pathology ; Mice ; Stem Cells ; Wnt Proteins/genetics ; Wnt Signaling Pathway ; beta Catenin/therapeutic use

المؤلفون: Rodriguez-Hernandez I; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Maiques O; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Kohlhammer L; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK., Cantelli G; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Department of Medicine, Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC, USA., Perdrix-Rosell A; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Tumour Host Interaction Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK., Monger J; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK., Fanshawe B; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, Kings' College London, London, SE1 7EH, UK., Bridgeman VL; Tumour Host Interaction Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK., Karagiannis SN; St John's Institute of Dermatology, School of Basic & Medical Biosciences, King's College London and NIHR Biomedical Research Centre at Guy's and St Thomas' Hospitals and King's College London, London, SE1 9RT, UK., Penin RM; Department of Pathology, Hospital Universitari de Bellvitge, IDIBELL, l'Hospitalet de Llobregat, 08908, Barcelona, Spain., Marcolval J; Department of Dermatology, Hospital Universitari de Bellvitge, IDIBELL, l'Hospitalet de Llobregat, 08908, Barcelona, Spain., Marti RM; Department of Dermatology, Hospital Universitari Arnau de Vilanova, University of Lleida, IRB LleidaI, CIBERONC, 25198, Lleida, Spain., Matias-Guiu X; Department of Pathology and Molecular Genetics, Hospital Universitari Arnau de Vilanova, University of Lleida, IRB Lleida, CIBERONC, 25198, Lleida, Spain., Fruhwirth GO; Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, Kings' College London, London, SE1 7EH, UK., Orgaz JL; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK.; Instituto de Investigaciones Biomedicas 'Alberto Sols', CSIC-UAM, 28029, Madrid, Spain., Malanchi I; Tumour Host Interaction Laboratory, The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK., Sanz-Moreno V; Barts Cancer Institute, Queen Mary University of London, John Vane Science Building, Charterhouse Square, London, EC1M 6BQ, UK. v.sanz-moreno@qmul.ac.uk.; Randall Division of Cell and Molecular Biophysics, New Hunt's House, Guy's Campus, King's College London, London, SE1 1UL, UK. v.sanz-moreno@qmul.ac.uk.

المصدر: Nature communications [Nat Commun] 2020 Oct 20; Vol. 11 (1), pp. 5315. Date of Electronic Publication: 2020 Oct 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Frizzled Receptors/*metabolism , Melanoma/*metabolism , Microfilament Proteins/*metabolism , Wnt Proteins/*metabolism , rho GTP-Binding Proteins/*metabolism, Animals ; Cell Transformation, Neoplastic ; Female ; Frizzled Receptors/genetics ; Humans ; Male ; Melanoma/genetics ; Melanoma/pathology ; Mice ; Mice, SCID ; Microfilament Proteins/genetics ; Myosin Type II/genetics ; Myosin Type II/metabolism ; Neoplasm Invasiveness ; Signal Transduction ; Wnt Proteins/genetics ; rho GTP-Binding Proteins/genetics ; rho-Associated Kinases/genetics ; rho-Associated Kinases/metabolism

المؤلفون: Pascual-Carreras E; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain., Marín-Barba M; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK., Castillo-Lara S; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain., Coronel-Córdoba P; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain., Magri MS; Centro Andaluz de Biología del Desarollo (CABD), Universidad Pablo de Olavide, Sevilla, Spain., Wheeler GN; School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK., Gómez-Skarmeta JL; Centro Andaluz de Biología del Desarollo (CABD), Universidad Pablo de Olavide, Sevilla, Spain., Abril JF; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain., Saló E; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain. esalo@ub.edu., Adell T; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona (UB) & Institute of Biomedicine of Universitat de Barcelona (IBUB), Barcelona, Spain. tadellc@ub.edu.

المصدر: Nature communications [Nat Commun] 2023 Jan 18; Vol. 14 (1), pp. 298. Date of Electronic Publication: 2023 Jan 18.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Planarians*/physiology, Animals ; Wnt Proteins/genetics ; Wnt Proteins/metabolism ; Chromatin Assembly and Disassembly ; beta Catenin/genetics ; beta Catenin/metabolism ; Body Patterning/genetics

المؤلفون: Fendler A; Cancer Research Program, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.; Berlin Institute of Health (BIH), Berlin, Germany.; Department of Urology, Charité-University Medicine, Berlin, Germany.; Berlin Institute for Urologic Research, Berlin, Germany., Bauer D; Cancer Research Program, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany., Busch J; Berlin Institute of Health (BIH), Berlin, Germany.; Department of Urology, Charité-University Medicine, Berlin, Germany., Jung K; Department of Urology, Charité-University Medicine, Berlin, Germany.; Berlin Institute for Urologic Research, Berlin, Germany., Wulf-Goldenberg A; Experimental Pharmacology and Oncology GmbH (EPO), Berlin, Germany., Kunz S; Electron Microscopy Core Facility, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany., Song K; Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany., Myszczyszyn A; Cancer Research Program, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany., Elezkurtaj S; Department of Pathology, Charité-University Medicine, Berlin, Germany., Erguen B; Department of Urology, Charité-University Medicine, Berlin, Germany., Jung S; Cancer Research Program, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany., Chen W; Berlin Institute of Health (BIH), Berlin, Germany.; Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.; Department of Biology, Southern University of Science and Technology, Shenzhen, China., Birchmeier W; Cancer Research Program, Max Delbrueck Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany. wbirch@mdc-berlin.de.; Berlin Institute of Health (BIH), Berlin, Germany. wbirch@mdc-berlin.de.

المصدر: Nature communications [Nat Commun] 2020 Feb 17; Vol. 11 (1), pp. 929. Date of Electronic Publication: 2020 Feb 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Carcinoma, Renal Cell/*drug therapy , Kidney Neoplasms/*drug therapy , Neoplastic Stem Cells/*drug effects , Receptors, Notch/*antagonists & inhibitors , Wnt Proteins/*antagonists & inhibitors, Adult ; Aged ; Aged, 80 and over ; Animals ; Antineoplastic Agents/therapeutic use ; Bridged Bicyclo Compounds, Heterocyclic/pharmacology ; Carcinoma, Renal Cell/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Female ; Heterocyclic Compounds, 3-Ring/pharmacology ; Humans ; Kidney/pathology ; Kidney Neoplasms/pathology ; Male ; Mice ; Middle Aged ; Neoplastic Stem Cells/pathology ; Primary Cell Culture ; Pyrimidinones/pharmacology ; RNA, Small Interfering/metabolism ; Receptors, Notch/metabolism ; Signal Transduction/drug effects ; Single-Cell Analysis ; Spheroids, Cellular ; Wnt Proteins/metabolism ; Xenograft Model Antitumor Assays

المؤلفون: Seishima R; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Leung C; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Yada S; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Murad KBA; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Tan LT; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Hajamohideen A; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Tan SH; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Itoh H; A*STAR Skin Research Institute of Singapore, Singapore, 138648, Singapore., Murakami K; Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan., Ishida Y; Department of Dermatology, Kyoto University, Yoshida-Konoe-cho, Sakyo-ku, 606-8501, Japan., Nakamizo S; A*STAR Skin Research Institute of Singapore, Singapore, 138648, Singapore., Yoshikawa Y; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Wong E; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore., Barker N; A*STAR Institute of Medical Biology, Singapore, 138648, Singapore. Nicholas.barker@imb.a-star.edu.sg.; Cancer Research Institute, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan. Nicholas.barker@imb.a-star.edu.sg.; School of Biological Sciences, Nanyang Technological University, Singapore, 308232, Singapore. Nicholas.barker@imb.a-star.edu.sg.

المصدر: Nature communications [Nat Commun] 2019 Nov 26; Vol. 10 (1), pp. 5378. Date of Electronic Publication: 2019 Nov 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Stem Cells*/cytology , Stem Cells*/physiology, Receptors, G-Protein-Coupled/*metabolism , Uterus/*growth & development , Wnt Proteins/*metabolism, Animals ; Cell Lineage ; Endometrium/growth & development ; Female ; Gene Expression Regulation, Developmental ; Mice, Transgenic ; Mullerian Ducts/cytology ; Organoids ; Pregnancy ; Receptors, G-Protein-Coupled/genetics ; Wnt Proteins/genetics

المؤلفون: Gao L; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China.; College of Life Sciences, Beijing Normal University, 100875, Beijing, China., Hu Y; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Tian Y; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Fan Z; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China.; College of Biological Sciences, China Agricultural University, 100094, Beijing, China., Wang K; Key Laboratory of Molecular Imaging, Institute of Automation, Chinese Academy of Sciences, 100190, Beijing, China., Li H; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Zhou Q; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Zeng G; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Hu X; The University of Texas Health Science Center at Houston (UTHealth), 2450 Holcombe Blvd., Suite 1, Houston, TX, 77021, USA., Yu L; Beijing Tongren Hospital, Capital Medical University, 100730, Beijing, China., Zhou S; State Key Laboratory of Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China., Tong X; State Key Laboratory of Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Huang H; State Key Laboratory of Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China.; Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China., Chen H; Department of Thoracic Surgery, Fudan University Shanghai Cancer Center, 200032, Shanghai, China., Liu Q; High Magnetic Field Laboratory, Chinese Academy of Sciences, 230031, Hefei, Anhui, China., Liu W; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Zhang G; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China., Zeng M; Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China., Zhou G; State Key Laboratory of Molecular Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China., He Q; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China. tqyhe@email.jnu.edu.cn., Ji H; State Key Laboratory of Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China. hbji@sibcb.ac.cn.; CAS Center for Excellence in Molecular Cell Science, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China. hbji@sibcb.ac.cn.; Innovation Center for Cell Signaling Network, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200031, Shanghai, China. hbji@sibcb.ac.cn.; School of Life Science and Technology, Shanghai Tech University, 200120, Shanghai, China. hbji@sibcb.ac.cn., Chen L; Key Laboratory of Functional Protein Research of Guangdong Higher Education, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, 510632, Guangzhou, China. chenliang@jnu.edu.cn.

المصدر: Nature communications [Nat Commun] 2019 Apr 10; Vol. 10 (1), pp. 1665. Date of Electronic Publication: 2019 Apr 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic* , Genes, Tumor Suppressor*, GATA4 Transcription Factor/*metabolism , Lung Neoplasms/*genetics , Wnt Proteins/*metabolism, A549 Cells ; Animals ; Cellular Senescence/genetics ; Down-Regulation ; Female ; GATA4 Transcription Factor/genetics ; Gene Knockdown Techniques ; HEK293 Cells ; Humans ; Lung/pathology ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Male ; Mice ; Mice, Nude ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Middle Aged ; Prognosis ; Receptor, Transforming Growth Factor-beta Type I/antagonists & inhibitors ; Receptor, Transforming Growth Factor-beta Type I/metabolism ; Signal Transduction/genetics ; Smad2 Protein/genetics ; Smad2 Protein/metabolism ; Smad4 Protein/genetics ; Smad4 Protein/metabolism ; Transforming Growth Factor beta2/metabolism ; Up-Regulation ; Wnt Proteins/genetics ; Xenograft Model Antitumor Assays