المؤلفون: Rodin, S, Antonsson, L, Niaudet, C, Simonson, OE, Salmela, E, Hansson, EM, Domogatskaya, A, Xiao, ZJ, Damdimopoulou, P, Sheikhi, M, Inzunza, J, Nilsson, AS, Baker, D, Kuiper, R, Sun, Y, Blennow, E, Nordenskjold, M, Grinnemo, KH, Kere, J, Betsholtz, C, Hovatta, O, Tryggvason, K

المصدر: Nature communications. 5:3195

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:128264658

المؤلفون: Qin K; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Yu S; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Liu Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Guo R; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Guo S; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Fei J; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Wang Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Jia K; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Xu Z; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 610041, Chengdu, China., Chen H; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China.; Department of Cardiothoracic Surgery, First Affiliated Hospital of Chengdu Medical College, 610500, Chengdu, China., Li F; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Niu M; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Dai MS; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA., Dai L; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 610041, Chengdu, China., Cao Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Zhang Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China., Xiao ZJ; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China. jimzx@scu.edu.cn.; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, 610041, Chengdu, China. jimzx@scu.edu.cn., Yi Y; Center of Growth, Metabolism and Aging, Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, 610064, Chengdu, China. yy-yiyong@scu.edu.cn.

المصدر: Nature communications [Nat Commun] 2023 Oct 13; Vol. 14 (1), pp. 6473. Date of Electronic Publication: 2023 Oct 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , Leukemia*, Humans ; Cell Survival ; Ribosomes ; Cell Nucleolus ; Ubiquitin Thiolesterase

المؤلفون: Li J; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Wang Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China. wangy90@scu.edu.cn., Luo Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Liu Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Yi Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Li J; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Pan Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Li W; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., You W; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Hu Q; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Zhao Z; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Zhang Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Cao Y; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China., Zhang L; State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), Beijing Institute of Lifeomics, Beijing, 100850, China., Yuan J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 100 Haike Rd, Pudong, Shanghai, 201210, China., Xiao ZJ; Center of Growth, Metabolism and Aging, College of Life Sciences, Sichuan University, Chengdu, 610065, China. jimzx@scu.edu.cn.; State Key Laboratory of Biotherapy, Sichuan University, Chengdu, 610041, China. jimzx@scu.edu.cn.

المصدر: Nature communications [Nat Commun] 2022 Dec 17; Vol. 13 (1), pp. 7799. Date of Electronic Publication: 2022 Dec 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms*/genetics , Lung Neoplasms*/metabolism , Lung Neoplasms*/pathology , Tumor Suppressor Protein p53*/genetics , Tumor Suppressor Protein p53*/metabolism, Animals ; Mice ; Beclin-1/genetics ; Beclin-1/metabolism ; Genes, ras ; Mutation ; Proto-Oncogene Proteins p21(ras)/genetics ; Proto-Oncogene Proteins p21(ras)/metabolism ; Ubiquitin-Specific Proteases/genetics ; Ubiquitin-Specific Proteases/metabolism

المؤلفون: Niu M; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Xu J; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Liu Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Li Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., He T; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Ding L; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., He Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Yi Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Li F; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Guo R; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Gao Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Li R; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Li L; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Fu M; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Hu Q; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Luo Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Zhang C; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Qin K; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Yi J; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Yu S; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Yang J; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Chen H; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Wang L; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Li Z; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Dong B; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China., Qi S; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China., Ouyang L; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China., Zhang Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China., Cao Y; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China. cao@scu.edu.cn., Xiao ZJ; Center of Growth, Metabolism, and Aging, Key Laboratory of Bio-Resource and Eco-Environment, Ministry of Education, College of Life Sciences, Sichuan University, Chengdu, China. jimzx@scu.edu.cn.; State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China. jimzx@scu.edu.cn.

المصدر: Nature communications [Nat Commun] 2021 Oct 11; Vol. 12 (1), pp. 5919. Date of Electronic Publication: 2021 Oct 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*genetics , F-Box Proteins/*genetics , Lung Neoplasms/*genetics , Membrane Glycoproteins/*genetics, Acrylamides/pharmacology ; Aniline Compounds/pharmacology ; Animals ; Antineoplastic Agents/pharmacology ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/mortality ; Carcinoma, Non-Small-Cell Lung/pathology ; Cell Line, Tumor ; Cell Movement/drug effects ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Drug Synergism ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; F-Box Proteins/metabolism ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/mortality ; Lung Neoplasms/pathology ; Membrane Glycoproteins/metabolism ; Mice ; Mice, Nude ; Nebivolol/pharmacology ; Protein Kinase Inhibitors/pharmacology ; Signal Transduction ; Survival Analysis ; Tumor Burden/drug effects ; Xenograft Model Antitumor Assays