المؤلفون: Pardons M; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., Cole B; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., Lambrechts L; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium.; BioBix, Department of Data Analysis and Mathematical Modelling, Faculty of Bioscience Engineering, Ghent University, 9000, Ghent, Belgium., van Snippenberg W; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., Rutsaert S; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., Noppe Y; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., De Langhe N; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium., Dhondt A; Department of Nephrology, Ghent University Hospital, 9000, Ghent, Belgium., Vega J; Arcturus Therapeutics, 10628 Science Center Drive, Suite 250, San Diego, 92121, CA, USA., Eyassu F; Computational biology, Johnson and Johnson, 2340, Beerse, Belgium., Nijs E; Janssen infectious diseases and diagnostics, Johnson and Johnson, 2340, Beerse, Belgium., Van Gulck E; Janssen infectious diseases and diagnostics, Johnson and Johnson, 2340, Beerse, Belgium., Boden D; Janssen Biopharma, Johnson and Johnson, South San Francisco, 94080, CA, USA., Vandekerckhove L; HIV Cure Research Center, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent University, 9000, Ghent, Belgium. linos.vandekerckhove@ugent.be.

المصدر: Nature communications [Nat Commun] 2023 Dec 18; Vol. 14 (1), pp. 8397. Date of Electronic Publication: 2023 Dec 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Virus Latency*/drug effects , Virus Latency*/genetics , Gene Products, tat*/genetics , Gene Products, tat*/metabolism , RNA, Viral*/administration & dosage , RNA, Viral*/genetics , RNA, Viral*/metabolism , Nanoparticles*/administration & dosage , Nanoparticles*/chemistry , HIV-1*/drug effects , HIV-1*/genetics, HIV Infections/drug therapy ; HIV Infections/genetics ; HIV Infections/virology ; Panobinostat/pharmacology ; Antiretroviral Therapy, Highly Active ; CD4-Positive T-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/virology ; CD4 Antigens/genetics ; CD4 Antigens/metabolism ; Proviruses/drug effects ; Proviruses/genetics ; Single-Cell Gene Expression Analysis ; HIV Core Protein p24/genetics ; HIV Core Protein p24/metabolism ; RNA, Long Noncoding/metabolism ; Cells, Cultured ; Humans ; Ionomycin/pharmacology

المؤلفون: Jin J; National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Department of Cell Biology, School of Basic Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, 300070, Tianjin, China., Bai H; National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Department of Cell Biology, School of Basic Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, 300070, Tianjin, China., Yan H; National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Department of Cell Biology, School of Basic Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, 300070, Tianjin, China., Deng T; Key Laboratory of Breast Cancer Prevention and Therapy of Ministry of Education, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, 300060, Tianjin, China., Li T; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, 430071, Wuhan, China., Xiao R; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, 430071, Wuhan, China., Fan L; Department of Infectious Diseases, Tianjin Second People's Hospital, Nankai University, 300192, Tianjin, China., Bai X; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China., Ning H; National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Department of Cell Biology, School of Basic Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, 300070, Tianjin, China., Liu Z; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China., Zhang K; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China., Wu X; The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, 300070, Tianjin, China., Liang K; Department of Pathophysiology, School of Basic Medical Sciences, Wuhan University, 430071, Wuhan, China., Ma P; Department of Infectious Diseases, Tianjin Second People's Hospital, Nankai University, 300192, Tianjin, China. docmaping@outlook.com., Gao X; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 300020, Tianjin, China. gaoxin1@ihcams.ac.cn.; Tianjin Institutes of Health Science, 301600, Tianjin, China. gaoxin1@ihcams.ac.cn., Hu D; National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, State Key Laboratory of Experimental Hematology, Key Laboratory of Immune Microenvironment and Disease of Ministry of Education, Department of Cell Biology, School of Basic Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, 300070, Tianjin, China. hudq@tmu.edu.cn.

المصدر: Nature communications [Nat Commun] 2023 Nov 10; Vol. 14 (1), pp. 7274. Date of Electronic Publication: 2023 Nov 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1*/physiology , HIV Infections*/genetics, Humans ; Transcriptional Elongation Factors/metabolism ; Cell Line ; Proviruses/genetics ; T-Lymphocytes/metabolism ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism ; Virus Latency/genetics ; Protein-Arginine N-Methyltransferases/genetics ; Protein-Arginine N-Methyltransferases/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism

المؤلفون: Zhou Q; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA., Kunder N; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA., De la Paz JA; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA., Lasley AE; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA., Bhat VD; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA., Morcos F; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA. Faruckm@utdallas.edu.; Center for Systems Biology, University of Texas at Dallas, Richardson, TX, 75080, USA. Faruckm@utdallas.edu., Campbell ZT; Department of Biological Sciences, University of Texas at Dallas, Richardson, TX, 75080, USA. Zachary.Campbell@utdallas.edu.

المصدر: Nature communications [Nat Commun] 2018 Jun 28; Vol. 9 (1), pp. 2511. Date of Electronic Publication: 2018 Jun 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Products, tat/*chemistry , RNA/*chemistry , RNA Nucleotidyltransferases/*chemistry , RNA-Binding Proteins/*chemistry , Viral Regulatory and Accessory Proteins/*chemistry, Amino Acid Sequence ; Bacteriophage lambda/chemistry ; Binding Sites ; Cloning, Molecular ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Gene Expression ; Gene Products, tat/genetics ; Gene Products, tat/metabolism ; Genetic Vectors/chemistry ; Genetic Vectors/metabolism ; High-Throughput Nucleotide Sequencing ; Humans ; Immunodeficiency Virus, Bovine/chemistry ; Models, Molecular ; Nucleic Acid Conformation ; Protein Binding ; Protein Structure, Secondary ; RNA/genetics ; RNA/metabolism ; RNA Nucleotidyltransferases/genetics ; RNA Nucleotidyltransferases/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Recombinant Proteins/chemistry ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Sequence Analysis, RNA ; Viral Regulatory and Accessory Proteins/genetics ; Viral Regulatory and Accessory Proteins/metabolism

المؤلفون: Chang Z; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China., Jiang N; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China., Zhang Y; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China., Lu H; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China., Yin J; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China., Wahlgren M; Institute of Microbiology, Tumour and Cellular Biology, Karolinska Institutet, Nobels väg 16, S-171 77 Stockholm, Sweden., Cheng X; Department of Pathogen Biology, Fudan University, Handan Road 220, Shanghai 200433, China., Cao Y; Department of Immunology, China Medical University, Puhe Road 77, Shenyang 110122, China., Chen Q; Key Laboratory of Zoonosis, Jilin University, Xi An Da Lu 5333, Changchun 130062, China.; Institute of Microbiology, Tumour and Cellular Biology, Karolinska Institutet, Nobels väg 16, S-171 77 Stockholm, Sweden.; Key Laboratory of Zoonosis, Shenyang Agricultural University, Dongling Road 120, Shenyang 10866, China.

المصدر: Nature communications [Nat Commun] 2016 May 06; Vol. 7, pp. 11537. Date of Electronic Publication: 2016 May 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Deoxyribonucleases/*immunology , Extracellular Traps/*immunology , Gene Products, tat/*immunology , Virulence Factors/*immunology, Animals ; Deoxyribonucleases/genetics ; Deoxyribonucleases/metabolism ; Gene Knockout Techniques ; Gene Products, tat/genetics ; Gene Products, tat/metabolism ; Malaria Vaccines ; Malaria, Falciparum/prevention & control ; Mice ; Plasmodium berghei/genetics ; Plasmodium berghei/immunology ; Plasmodium berghei/metabolism ; Plasmodium falciparum/genetics ; Plasmodium falciparum/immunology ; Plasmodium falciparum/metabolism ; Vaccination ; Virulence Factors/genetics ; Virulence Factors/metabolism

المؤلفون: Tantale K; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France., Garcia-Oliver E; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France., Robert MC; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France.; Institut de Génétique Humaine, University of Montpellier, CNRS, Montpellier, France., L'Hostis A; LPHI, UMR CNRS 5235, University of Montpellier, Montpellier, France., Yang Y; LPHI, UMR CNRS 5235, University of Montpellier, Montpellier, France., Tsanov N; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France., Topno R; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France.; Institut de Génétique Humaine, University of Montpellier, CNRS, Montpellier, France.; LPHI, UMR CNRS 5235, University of Montpellier, Montpellier, France., Gostan T; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France., Kozulic-Pirher A; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France., Basu-Shrivastava M; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France., Mukherjee K; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France., Slaninova V; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France.; Institut de Génétique Humaine, University of Montpellier, CNRS, Montpellier, France., Andrau JC; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France., Mueller F; Unité Imagerie et Modélisation, Institut Pasteur and CNRS UMR 3691, Paris, France., Basyuk E; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France. Eugenia.Basyuk@u-bordeaux.fr.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France. Eugenia.Basyuk@u-bordeaux.fr.; Microbiology Fundamental and Pathogenicity CNRS UMR 5234, University of Bordeaux, Bordeaux, France. Eugenia.Basyuk@u-bordeaux.fr., Radulescu O; LPHI, UMR CNRS 5235, University of Montpellier, Montpellier, France. Ovidiu.Radulescu@umontpellier.fr., Bertrand E; Institut de Génétique Moléculaire de Montpellier, University of Montpellier, CNRS, Montpellier, France. Edouard.Bertrand@igh.cnrs.fr.; Equipe labélisée Ligue Nationale Contre le Cancer, University of Montpellier, CNRS, Montpellier, France. Edouard.Bertrand@igh.cnrs.fr.; Institut de Génétique Humaine, University of Montpellier, CNRS, Montpellier, France. Edouard.Bertrand@igh.cnrs.fr.

المصدر: Nature communications [Nat Commun] 2021 Jul 23; Vol. 12 (1), pp. 4503. Date of Electronic Publication: 2021 Jul 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Viral*, HIV Infections/*genetics , HIV-1/*genetics , Promoter Regions, Genetic/*genetics , Virus Latency/*genetics, Algorithms ; DNA-Directed RNA Polymerases/metabolism ; HIV Infections/metabolism ; HIV Infections/virology ; HIV-1/physiology ; HeLa Cells ; Humans ; Models, Genetic ; Stochastic Processes ; Time Factors ; Virus Activation/genetics ; tat Gene Products, Human Immunodeficiency Virus/genetics

المؤلفون: Debaisieux S; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Lachambre S; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Gross A; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Mettling C; IGH, UPR 1142 CNRS, 141 Rue de la Cardonille, 34396 Montpellier, France., Besteiro S; DIMNP, UMR 5235 CNRS, Université de Montpellier, 34095 Montpellier, France., Yezid H; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Henaff D; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Chopard C; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Mesnard JM; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France., Beaumelle B; CPBS, UMR 5236 CNRS-Université de Montpellier, 1919 Route de Mende, 34293 Montpellier, France.

المصدر: Nature communications [Nat Commun] 2015 Feb 04; Vol. 6, pp. 6211. Date of Electronic Publication: 2015 Feb 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: HIV-1/*physiology , Macrophages/*drug effects , Monocytes/*drug effects , Neutrophils/*drug effects , Phagocytosis/*drug effects , tat Gene Products, Human Immunodeficiency Virus/*pharmacology, Bystander Effect ; Gene Expression Regulation ; Host-Pathogen Interactions ; Humans ; Lectins, C-Type/antagonists & inhibitors ; Lectins, C-Type/genetics ; Lectins, C-Type/metabolism ; Macrophages/metabolism ; Macrophages/ultrastructure ; Mannose Receptor ; Mannose-Binding Lectins/antagonists & inhibitors ; Mannose-Binding Lectins/genetics ; Mannose-Binding Lectins/metabolism ; Monocytes/metabolism ; Monocytes/ultrastructure ; Mycobacterium avium/growth & development ; Neutrophils/metabolism ; Neutrophils/ultrastructure ; Phosphatidylinositol 4,5-Diphosphate/antagonists & inhibitors ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Primary Cell Culture ; Protein Transport/drug effects ; Pseudopodia/drug effects ; Pseudopodia/metabolism ; Pseudopodia/ultrastructure ; Receptors, Cell Surface/antagonists & inhibitors ; Receptors, Cell Surface/genetics ; Receptors, Cell Surface/metabolism ; Receptors, IgG/antagonists & inhibitors ; Receptors, IgG/genetics ; Receptors, IgG/metabolism ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/pharmacology ; Signal Transduction ; Toxoplasma/growth & development ; cdc42 GTP-Binding Protein/genetics ; cdc42 GTP-Binding Protein/metabolism ; tat Gene Products, Human Immunodeficiency Virus/biosynthesis

المؤلفون: Gee P; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida Ushinomiya-cho, Sakyo-ku, Kyoto, 606-8507, Japan.; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan., Lung MSY; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Okuzaki Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Sasakawa N; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Iguchi T; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Makita Y; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan.; T-CiRA Discovery, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Hozumi H; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan.; T-CiRA Discovery, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Miura Y; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Yang LF; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Iwasaki M; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Wang XH; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Waller MA; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Shirai N; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Abe YO; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Fujita Y; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Watanabe K; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Kagita A; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Iwabuchi KA; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan., Yasuda M; Pathology Analysis Center, Central Institute for Experimental Animals, Kawasaki, Kanagawa, 210-0821, Japan., Xu H; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Noda T; Laboratory of Ultrastructural Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Komano J; Department of Clinical Laboratory, Nagoya Medical Center, 1-1 4-chome, Sannomaru, Naka-ku, Nagoya, 460-0001, Japan.; Department of Infection Control, Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka, 569-1041, Japan., Sakurai H; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan., Inukai N; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan.; T-CiRA Discovery, Takeda Pharmaceutical Company Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Hotta A; Center for iPS Cell Research and Application (CiRA), Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan. akitsu.hotta@cira.kyoto-u.ac.jp.; Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Yoshida Ushinomiya-cho, Sakyo-ku, Kyoto, 606-8507, Japan. akitsu.hotta@cira.kyoto-u.ac.jp.; Takeda-CiRA Joint Program (T-CiRA), Fujisawa, Kanagawa, Japan. akitsu.hotta@cira.kyoto-u.ac.jp.

المصدر: Nature communications [Nat Commun] 2020 Mar 13; Vol. 11 (1), pp. 1334. Date of Electronic Publication: 2020 Mar 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*, CRISPR-Associated Protein 9/*genetics , Exons/*genetics , Extracellular Vesicles/*metabolism , Nanoparticles/*chemistry , RNA, Guide, CRISPR-Cas Systems/*metabolism, Base Sequence ; Cell Survival ; Dimerization ; Gene Editing ; Genetic Vectors/metabolism ; HEK293 Cells ; HIV Protease/metabolism ; Humans ; Induced Pluripotent Stem Cells/metabolism ; Ligands ; Luciferases/metabolism ; RNA Splicing/genetics ; RNA, Catalytic/metabolism ; Ribonucleoproteins/metabolism ; Tissue Donors ; tat Gene Products, Human Immunodeficiency Virus/metabolism

المؤلفون: Pham VV; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA., Salguero C; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA.; Vice Presidency of Research, Universidad de los Andes, Bogotá, 111711, Colombia., Khan SN; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA.; Department of Pharmacy, East West University, Dhaka, 1212, Bangladesh., Meagher JL; Life Sciences Institute, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI, 48109, USA., Brown WC; Life Sciences Institute, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI, 48109, USA., Humbert N; Faculté de Pharmacie, Laboratoire de Bioimagerie et Pathologies, UMR 7021 du CNRS, Université de Strasbourg, 74 route du Rhin, 67401, Illkirch, France., de Rocquigny H; Faculté de Pharmacie, Laboratoire de Bioimagerie et Pathologies, UMR 7021 du CNRS, Université de Strasbourg, 74 route du Rhin, 67401, Illkirch, France.; Inserm - U1259 MAVIVH. Morphogenèse et Antigénicité du VIH et des Virus des Hépatites, 10 boulevard Tonnelle - BP 3223, 37032, Tours Cedex 1, France., Smith JL; Life Sciences Institute, University of Michigan, 210 Washtenaw Ave, Ann Arbor, MI, 48109, USA.; Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA., D'Souza VM; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USA. dsouza@mcb.harvard.edu.

المصدر: Nature communications [Nat Commun] 2018 Oct 15; Vol. 9 (1), pp. 4266. Date of Electronic Publication: 2018 Oct 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Molecular Mimicry*, RNA, Viral/*metabolism , Ribonucleoproteins, Small Nuclear/*metabolism , tat Gene Products, Human Immunodeficiency Virus/*metabolism, Humans ; Magnetic Resonance Spectroscopy ; Nucleic Acid Conformation ; RNA, Viral/chemistry ; RNA-Binding Proteins/metabolism

المؤلفون: Chopard C; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Tong PBV; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Tóth P; INCI, UPR 3212 CNRS, 5 rue Blaise Pascal, 67084, Strasbourg, France. petra.toth@inci-cnrs.unistra.fr., Schatz M; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Yezid H; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Debaisieux S; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Mettling C; IGH, UPR 1142 CNRS, 141 Rue de la Cardonille, 34396, Montpellier, France., Gross A; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Pugnière M; IRCM, INSERM U 1194, 208 Rue des Apothicaires, 34298, Montpellier, France., Tu A; INCI, UPR 3212 CNRS, 5 rue Blaise Pascal, 67084, Strasbourg, France., Strub JM; CNRS, IPHC UMR 7178, Université de Strasbourg, 67000, Strasbourg, France., Mesnard JM; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France., Vitale N; INCI, UPR 3212 CNRS, 5 rue Blaise Pascal, 67084, Strasbourg, France.; INSERM, 75654, Paris Cedex 13, France., Beaumelle B; IRIM, UMR 9004, Université de Montpellier-CNRS, 1919 Route de Mende, 34293, Montpellier, France. bruno.beaumelle@irim.cnrs.fr.

المصدر: Nature communications [Nat Commun] 2018 Jun 08; Vol. 9 (1), pp. 2251. Date of Electronic Publication: 2018 Jun 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cell Membrane/*metabolism , Cyclophilin A/*metabolism , HIV-1/*metabolism , tat Gene Products, Human Immunodeficiency Virus/*metabolism, Acyltransferases/metabolism ; Animals ; Animals, Newborn ; Cell Membrane/virology ; Cyclophilin A/genetics ; HEK293 Cells ; HIV-1/physiology ; Humans ; Jurkat Cells ; Lipoylation ; Mice ; Mice, Inbred C57BL ; PC12 Cells ; Phosphatidylinositol 4,5-Diphosphate/metabolism ; Protein Binding ; RAW 264.7 Cells ; Rats

المؤلفون: Bohn-Wippert K; Department of Bioengineering, University of Illinois at Urbana-Champaign, 1270 Digital Computer Lab, MC-278, 1304W Springfield Avenue, Urbana, Illinois 61801, USA., Tevonian EN; Department of Bioengineering, University of Illinois at Urbana-Champaign, 1270 Digital Computer Lab, MC-278, 1304W Springfield Avenue, Urbana, Illinois 61801, USA., Megaridis MR; Department of Bioengineering, University of Illinois at Urbana-Champaign, 1270 Digital Computer Lab, MC-278, 1304W Springfield Avenue, Urbana, Illinois 61801, USA., Dar RD; Department of Bioengineering, University of Illinois at Urbana-Champaign, 1270 Digital Computer Lab, MC-278, 1304W Springfield Avenue, Urbana, Illinois 61801, USA.; Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, 1206W Gregory Drive, Urbana, Illinois 61801, USA.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, 1110 West Green Street, Urbana, Illinois 61801, USA.

المصدر: Nature communications [Nat Commun] 2017 May 02; Vol. 8, pp. 15006. Date of Electronic Publication: 2017 May 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Host-Pathogen Interactions*, CD4-Positive T-Lymphocytes/*drug effects , Cell Movement/*drug effects , HIV-1/*drug effects , Promoter Regions, Genetic/*drug effects , Virus Activation/*drug effects, CD4-Positive T-Lymphocytes/metabolism ; CD4-Positive T-Lymphocytes/virology ; Depsipeptides/pharmacology ; Gene Expression Regulation ; HIV Long Terminal Repeat/genetics ; HIV-1/genetics ; HIV-1/growth & development ; HIV-1/metabolism ; HL-60 Cells ; Humans ; Hydroxamic Acids/pharmacology ; Indoles/pharmacology ; Ionomycin/pharmacology ; Jurkat Cells ; Panobinostat ; Phorbol Esters/pharmacology ; Primary Cell Culture ; Receptors, CXCR4/genetics ; Receptors, CXCR4/metabolism ; Tamoxifen/pharmacology ; Transcription, Genetic ; Tumor Necrosis Factor-alpha/pharmacology ; Virus Latency ; Vorinostat ; tat Gene Products, Human Immunodeficiency Virus/genetics ; tat Gene Products, Human Immunodeficiency Virus/metabolism