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المؤلفون: Wenjia Bai, Paul M. Matthews, Hideaki Suzuki, Nay Aung, Evangelos Evangelou, Yike Guo, Jian Huang, Daniel Rueckert, Martin R. Wilkins, Shuo Wang, Stefan K. Piechnik, Steffen E. Petersen, Declan P. O'Regan, Catherine Francis, Kenneth Fung, Giacomo Tarroni, Abbas Dehghan, Florian Guitton, Stefan Neubauer
المساهمون: Engineering & Physical Science Research Council (EPSRC), British Heart Foundation, Wellcome Trust, National Institute for Health Research, Imperial College Healthcare NHS Trust- BRC Funding
المصدر: Nat Med
مصطلحات موضوعية: Male, 0301 basic medicine, Genome-wide association study, Disease, Research & Experimental Medicine, Bioinformatics, RISK-TAKING, Machine Learning, TRACKING, 0302 clinical medicine, Image Processing, Computer-Assisted, Medicine, Phenomics, Aorta, 11 Medical and Health Sciences, Biological Specimen Banks, OUTCOMES, education.field_of_study, Anatomy, Cross-Sectional, medicine.diagnostic_test, Age Factors, Heart, General Medicine, GF, Magnetic Resonance Imaging, Biobank, 3. Good health, Cardiovascular physiology, Phenotype, Medicine, Research & Experimental, CARDIOVASCULAR-DISEASE, Cardiovascular Diseases, 030220 oncology & carcinogenesis, Heart Function Tests, MENDELIAN RANDOMIZATION, Female, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, PATHOPHYSIOLOGY, Immunology, Population, Phenome, Polymorphism, Single Nucleotide, Article, General Biochemistry, Genetics and Molecular Biology, Structure-Activity Relationship, 03 medical and health sciences, Sex Factors, LEFT-VENTRICULAR MASS, Mendelian randomization, Humans, Genetic Predisposition to Disease, education, HEALTH-CARE PROFESSIONALS, Science & Technology, business.industry, Myocardium, Magnetic resonance imaging, Cell Biology, BIRTH-WEIGHT, United Kingdom, 030104 developmental biology, business, RA, RC, Genome-Wide Association Study
وصف الملف: application/pdf
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المؤلفون: Axel Schambach, Martin Hauer-Jensen, Edward J. Kerschen, Snehalata A. Pawar, Hartmut Weiler, Jose A. Cancelas, Irene Hernandez, Marnie A. Ryan, José A. Fernández, Qiang Fu, Louis Fink, Hai Po H. Liang, Olga S. Kustikova, John H. Griffin, Hartmut Geiger, Kalpana Nattamai, Junru Wang, Karl-Uwe Petersen, Christopher Baum, Daohong Zhou
المصدر: Nature medicine
مصطلحات موضوعية: Thrombomodulin, Green Fluorescent Proteins, Biology, Pharmacology, Radiation Tolerance, General Biochemistry, Genetics and Molecular Biology, Article, law.invention, 03 medical and health sciences, Mice, 0302 clinical medicine, law, medicine, Animals, Humans, RNA, Messenger, Radiation Injuries, 030304 developmental biology, 0303 health sciences, General Medicine, Hematopoietic Stem Cells, Survival Analysis, Recombinant Proteins, 3. Good health, Mice, Inbred C57BL, Coagulation, Gene Expression Regulation, Apoptosis, 030220 oncology & carcinogenesis, Toxicity, Immunology, cardiovascular system, Recombinant DNA, Receptors, Thrombin, Signal transduction, Protein C, Whole-Body Irradiation, medicine.drug, Genetic screen, Signal Transduction
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3Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
المؤلفون: Estelle Bettelli, Thomas Korn, Jayagopala Reddy, Raymond A. Sobel, Terry B. Strom, Mohamed Oukka, Troels R. Petersen, Vijay K. Kuchroo, Kai W. Wucherpfennig, B Thomas Bäckström, Wenda Gao, Amit Awasthi
المصدر: Nature Medicine. 13:423-431
مصطلحات موضوعية: Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, Encephalomyelitis, Green Fluorescent Proteins, Autoimmunity, chemical and pharmacologic phenomena, medicine.disease_cause, T-Lymphocytes, Regulatory, Article, General Biochemistry, Genetics and Molecular Biology, Myelin oligodendrocyte glycoprotein, Mice, Myelin, immune system diseases, medicine, Animals, Glycoproteins, MHC class II, biology, Experimental autoimmune encephalomyelitis, Models, Immunological, Brain, FOXP3, Forkhead Transcription Factors, hemic and immune systems, General Medicine, medicine.disease, Immunohistochemistry, Peptide Fragments, medicine.anatomical_structure, Immunology, biology.protein, Myelin-Oligodendrocyte Glycoprotein, Tumor necrosis factor alpha, Immunotherapy