المؤلفون: Jin G; The Henan Luoyang Orthopedic Hospital, Zhengzhou, Henan, People's Republic of China.; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China.; Henan Provincial Cooperative Innovation Center of Cancer Chemoprevention, Zhengzhou University, Zhengzhou, Henan, People's Republic of China., Yan M; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China., Liu K; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China.; Henan Provincial Cooperative Innovation Center of Cancer Chemoprevention, Zhengzhou University, Zhengzhou, Henan, People's Republic of China.; Pathophysiology Department, School of Basic Medical Science, College of Medicine Zhengzhou University, Zhengzhou, Henan, People's Republic of China., Yao K; The Hormel Institute, University of Minnesota, Austin, MN, USA., Chen H; The Hormel Institute, University of Minnesota, Austin, MN, USA., Zhang C; Center of Bio Repository, Affiliated Tumor Hospital of Zhengzhou University, Zhengzhou, Henan, People's Republic of China., Yi Y; Department of Pathology and Pathophysiology, School of Basic Medical Sciences, Henan University of Chinese Medicine, Zhengzhou, Henan, People's Republic of China., Reddy K; The Hormel Institute, University of Minnesota, Austin, MN, USA., Gorja DR; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China., Laster KV; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China., Guo Z; The Henan Luoyang Orthopedic Hospital, Zhengzhou, Henan, People's Republic of China. Zhiping74@hotmail.com., Dong Z; China-US (Henan) Hormel Cancer Institute, Zhengzhou, People's Republic of China. zgdong@hci-cn.org.; Pathophysiology Department, School of Basic Medical Science, College of Medicine Zhengzhou University, Zhengzhou, Henan, People's Republic of China. zgdong@hci-cn.org.

المصدر: Oncogene [Oncogene] 2020 Oct; Vol. 39 (43), pp. 6733-6746. Date of Electronic Publication: 2020 Sep 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Colonic Neoplasms/*drug therapy , Protein Kinase Inhibitors/*pharmacology , Ribosomal Protein S6 Kinases, 90-kDa/*antagonists & inhibitors, Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Apoptosis ; Cell Line, Tumor ; Colonic Neoplasms/pathology ; Crystallography, X-Ray ; Drug Discovery ; Female ; HEK293 Cells ; Humans ; Mice ; Molecular Docking Simulation ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/therapeutic use ; Ribosomal Protein S6 Kinases, 90-kDa/metabolism ; Ribosomal Protein S6 Kinases, 90-kDa/ultrastructure ; Xenograft Model Antitumor Assays

المؤلفون: Shen H; Department of Oncology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, China.; Department of Oncology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China., Wang GC; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Li X; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.; Department of Thoracic Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China., Ge X; Department of Pathology, State Key lab of Reproductive Medicine, Nanjing Medical University, Nanjing, China., Wang M; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Shi ZM; Department of Pathology, State Key lab of Reproductive Medicine, Nanjing Medical University, Nanjing, China., Bhardwaj V; College of Pharmacy, Thomas Jefferson University, Philadelphia, PA 19107, USA., Wang ZX; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Zinner RG; Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA., Peiper SC; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Aplin AE; Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA., Jiang BH; Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IW 52242, USA., He J; Department of Pathology, Anatomy & Cell Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Jun.he@jefferson.edu.

المصدر: Oncogene [Oncogene] 2020 Dec; Vol. 39 (49), pp. 7181-7195. Date of Electronic Publication: 2020 Oct 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung/*pathology , Drug Resistance, Neoplasm/*drug effects , Lung Neoplasms/*pathology , Protein Kinase Inhibitors/*pharmacology , Ribosomal Protein S6 Kinases, 70-kDa/*antagonists & inhibitors, Adult ; Animals ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; ErbB Receptors/antagonists & inhibitors ; Humans ; Male ; Mice ; Mutation ; Prognosis ; Proto-Oncogene Proteins c-mdm2/metabolism ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Signal Transduction/drug effects ; Up-Regulation/drug effects

المؤلفون: Li LY; Department of Pharmacy, The Second Xiangya Hospital, Central South University, 410011, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, 410008, Changsha, China., Chen XS; Department of Pharmacy, The Second Xiangya Hospital, Central South University, 410011, Changsha, China., Wang KS; Department of Pathology, Xiangya hospital and Department of Pathology, School of Basic Medicine, Central South University, 410078, Changsha, China., Guan YD; Department of Pharmacy, The Second Xiangya Hospital, Central South University, 410011, Changsha, China., Ren XC; Department of Cancer Biology and Toxicology, Department of Pharmacology, College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Cao DS; Xiangya School of Pharmaceutical Sciences, Central South University, 410008, Changsha, China., Sun XY; Department of Pharmacy, The Second Xiangya Hospital, Central South University, 410011, Changsha, China.; Xiangya School of Pharmaceutical Sciences, Central South University, 410008, Changsha, China., Li AX; Xiangya School of Pharmaceutical Sciences, Central South University, 410008, Changsha, China., Tao YG; Cancer Research Institute, School of Basic Medicine, and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Central South University, 410078, Changsha, China., Zhang Y; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, 410008, Suzhou, China., Yin MZ; Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China., Wang XL; Translational Medicine R&D Center, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 518057, Shenzhen, China., Wu MH; Cancer Research Institute, School of Basic Medicine, and Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Central South University, 410078, Changsha, China., Yang JM; Department of Cancer Biology and Toxicology, Department of Pharmacology, College of Medicine, Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Cheng Y; Department of Pharmacy, The Second Xiangya Hospital, Central South University, 410011, Changsha, China. yancheng@csu.edu.cn.

المصدر: Oncogene [Oncogene] 2020 Oct; Vol. 39 (43), pp. 6704-6718. Date of Electronic Publication: 2020 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Autophagy*, AMP-Activated Protein Kinases/*metabolism , Antineoplastic Agents/*pharmacology , Breast Neoplasms/*pathology , Ribosomal Protein S6 Kinases, 90-kDa/*metabolism, Animals ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Breast Neoplasms/drug therapy ; Cell Nucleus/metabolism ; Drug Resistance, Neoplasm ; Endoplasmic Reticulum Stress/drug effects ; Endoribonucleases/metabolism ; Female ; Gene Knockdown Techniques ; Humans ; MAP Kinase Signaling System/drug effects ; MCF-7 Cells ; Mice ; Paclitaxel/pharmacology ; Paclitaxel/therapeutic use ; Phosphorylation ; Protein Serine-Threonine Kinases/metabolism ; Ribosomal Protein S6 Kinases, 90-kDa/genetics ; Xenograft Model Antitumor Assays

المؤلفون: Deng L; Department of Oncology, Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China.; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Qian G; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Zhang S; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA.; First Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China., Zheng H; Department of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China., Fan S; Department of Pathology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, P. R. China., Lesinski GB; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Owonikoko TK; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Ramalingam SS; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA., Sun SY; Department of Hematology and Medical Oncology, Emory University School of Medicine and Winship Cancer Institute, Atlanta, GA, USA. ssun@emory.edu.

المصدر: Oncogene [Oncogene] 2019 Aug; Vol. 38 (35), pp. 6270-6282. Date of Electronic Publication: 2019 Jul 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Sirolimus*/analogs & derivatives , Sirolimus*/pharmacology, B7-H1 Antigen/*metabolism , Mechanistic Target of Rapamycin Complex 1/*antagonists & inhibitors , Neoplasms/*metabolism , Ribosomal Protein S6 Kinases, 70-kDa/*antagonists & inhibitors , beta-Transducin Repeat-Containing Proteins/*metabolism, A549 Cells ; B7-H1 Antigen/genetics ; Benzoxazoles/pharmacology ; Cycloheximide/pharmacology ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation, Neoplastic/drug effects ; HCT116 Cells ; HEK293 Cells ; Humans ; Leupeptins/pharmacology ; MCF-7 Cells ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Morpholines/pharmacology ; Naphthyridines/pharmacology ; Neoplasms/genetics ; Neoplasms/pathology ; Protein Stability/drug effects ; Pyrimidines/pharmacology ; Ribosomal Protein S6 Kinases, 70-kDa/metabolism ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Tumor Cells, Cultured

المؤلفون: Chauvin C; 1] INSERM, U845, Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France., Koka V; 1] INSERM, U845, Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France., Nouschi A; 1] INSERM, U845, Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France., Mieulet V; 1] INSERM, U845, Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France., Hoareau-Aveilla C; Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse-UPS and Centre National de La Recherche Scientifique, Toulouse, France., Dreazen A; Department of Biochemistry and Molecular Biology, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Cagnard N; Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France., Carpentier W; Plateforme Post-Génomique Pitié-Salpétrière, Groupe Hospitalier Pitié-Salpétrière, Université Pierre et Marie Curie, Paris, France., Kiss T; Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse-UPS and Centre National de La Recherche Scientifique, Toulouse, France., Meyuhas O; Department of Biochemistry and Molecular Biology, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem, Israel., Pende M; 1] INSERM, U845, Paris, France [2] Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, UMRS-845, Paris, France.

المصدر: Oncogene [Oncogene] 2014 Jan 23; Vol. 33 (4), pp. 474-83. Date of Electronic Publication: 2013 Jan 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Protein Biosynthesis/*physiology , Ribosomal Protein S6 Kinases/*metabolism , Ribosomes/*enzymology, Animals ; Blotting, Northern ; Blotting, Western ; Gene Knock-In Techniques ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oligonucleotide Array Sequence Analysis ; Phosphorylation ; Real-Time Polymerase Chain Reaction ; Ribosomal Protein S6/metabolism ; Transcription, Genetic/physiology ; Transcriptome

المؤلفون: Alesi GN; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Jin L; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Li D; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Magliocca KR; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA., Kang Y; Department of Molecular Biology, Princeton University, Princeton, NJ, USA., Chen ZG; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Shin DM; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Khuri FR; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA., Kang S; Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA, USA.

المصدر: Oncogene [Oncogene] 2016 Oct 13; Vol. 35 (41), pp. 5412-5421. Date of Electronic Publication: 2016 Apr 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms/*genetics , Neoplasm Metastasis/*genetics , Ribosomal Protein S6 Kinases, 90-kDa/*genetics , Stathmin/*genetics, A549 Cells ; Cell Movement/genetics ; Gene Knockdown Techniques ; Humans ; Lung Neoplasms/pathology ; Microtubules/genetics ; Microtubules/pathology ; Neoplasm Invasiveness/genetics ; Neoplasm Invasiveness/pathology ; Neoplasm Metastasis/pathology ; Phosphorylation ; Ribosomal Protein S6 Kinases, 90-kDa/metabolism ; Signal Transduction ; Stathmin/metabolism

المؤلفون: Seto-Tetsuo F; Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan., Arioka M; Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan. arioka.masaki.118@m.kyushu-u.ac.jp., Miura K; Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan., Inoue T; Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan., Igawa K; Institute for Materials Chemistry and Engineering, Kyushu University, Kasuga, Japan., Tomooka K; Institute for Materials Chemistry and Engineering, Kyushu University, Kasuga, Japan., Takahashi-Yanaga F; Department of Pharmacology, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan., Sasaguri T; Department of Clinical Pharmacology, Faculty of Medical Sciences, Kyushu University, Fukuoka, Japan. sasaguri.toshiyuki.922@m.kyushu-u.ac.jp.

المصدر: Oncogene [Oncogene] 2021 Sep; Vol. 40 (37), pp. 5579-5589. Date of Electronic Publication: 2021 Jul 24.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Mechanistic Target of Rapamycin Complex 1* , Triple Negative Breast Neoplasms*, AMP-Activated Protein Kinases ; Animals ; Humans ; Mice ; Ribosomal Protein S6 Kinases, 70-kDa ; Signal Transduction

المؤلفون: Cronin R; School of Life Sciences, University of Essex, Colchester, UK., Brooke GN; School of Life Sciences, University of Essex, Colchester, UK. gbrooke@essex.ac.uk., Prischi F; School of Life Sciences, University of Essex, Colchester, UK. fprischi@essex.ac.uk.

المصدر: Oncogene [Oncogene] 2021 Jun; Vol. 40 (22), pp. 3775-3785. Date of Electronic Publication: 2021 May 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Androgen Antagonists/*therapeutic use , Prostatic Neoplasms/*enzymology , Prostatic Neoplasms, Castration-Resistant/*enzymology , Ribosomal Protein S6 Kinases, 90-kDa/*metabolism, Humans ; MAP Kinase Signaling System ; Male ; Phosphorylation ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms, Castration-Resistant/drug therapy ; Prostatic Neoplasms, Castration-Resistant/metabolism ; Prostatic Neoplasms, Castration-Resistant/pathology ; Receptors, Androgen/metabolism ; Signal Transduction

المؤلفون: Karra L; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA., Romero-Moya D; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA., Ksionda O; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA.; Liggins Institute, The University of Auckland, Auckland, New Zealand., Krush M; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA., Gu Z; Department of Pathology and Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Mues M; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA.; Miltenyi Biotec GmbH, Friedrich-Ebert-Str. 68, 51429, Bergisch Gladbach, Germany., Depeille P; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA., Mullighan C; Department of Pathology and Hematological Malignancies Program, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Roose JP; Department of Anatomy, University of California, San Francisco, San Francisco, CA, 94143, USA. jeroen.roose@ucsf.edu.

المصدر: Oncogene [Oncogene] 2020 Nov; Vol. 39 (45), pp. 6920-6934. Date of Electronic Publication: 2020 Sep 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins/*metabolism , Guanine Nucleotide Exchange Factors/*metabolism , Hematopoiesis/*physiology , Hematopoietic Stem Cells/*pathology , Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/*pathology, Animals ; Bone Marrow/pathology ; Cells, Cultured ; Child ; Colony-Forming Units Assay ; DNA-Binding Proteins/genetics ; Disease Models, Animal ; Female ; Gene Expression Regulation, Leukemic ; Guanine Nucleotide Exchange Factors/genetics ; Hematopoietic Stem Cell Transplantation ; Humans ; Male ; Mice ; Mice, Transgenic ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/genetics ; Primary Cell Culture ; Ribosomal Protein S6 Kinases/metabolism ; Signal Transduction/genetics ; TOR Serine-Threonine Kinases/metabolism ; Transplantation Chimera

المؤلفون: Dodd KM; Institute of Cancer and Genetics, Cardiff University, Cardiff, UK., Yang J; Institute of Cancer and Genetics, Cardiff University, Cardiff, UK., Shen MH; Institute of Cancer and Genetics, Cardiff University, Cardiff, UK., Sampson JR; Institute of Cancer and Genetics, Cardiff University, Cardiff, UK., Tee AR; Institute of Cancer and Genetics, Cardiff University, Cardiff, UK.

المصدر: Oncogene [Oncogene] 2015 Apr 23; Vol. 34 (17), pp. 2239-50. Date of Electronic Publication: 2014 Jun 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE

مواضيع طبية MeSH: Signal Transduction*, Carrier Proteins/*metabolism , Cystadenocarcinoma/*metabolism , Hypoxia-Inducible Factor 1, alpha Subunit/*metabolism , Kidney Neoplasms/*metabolism , Multiprotein Complexes/*metabolism , Neoplasm Proteins/*metabolism , Phosphoproteins/*metabolism , Ribosomal Protein S6 Kinases, 90-kDa/*metabolism , STAT3 Transcription Factor/*metabolism , TOR Serine-Threonine Kinases/*metabolism , Vascular Endothelial Growth Factor A/*metabolism, Adaptor Proteins, Signal Transducing ; Animals ; Carrier Proteins/genetics ; Cell Cycle Proteins ; Cell Hypoxia/genetics ; Cystadenocarcinoma/genetics ; Cystadenocarcinoma/pathology ; Eukaryotic Initiation Factors ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Hypoxia-Inducible Factor 1, alpha Subunit/genetics ; Kidney Neoplasms/genetics ; Kidney Neoplasms/pathology ; Mechanistic Target of Rapamycin Complex 1 ; Mice ; Mice, Knockout ; Multiprotein Complexes/genetics ; Neoplasm Proteins/genetics ; Phosphoproteins/genetics ; Ribosomal Protein S6 Kinases, 90-kDa/genetics ; STAT3 Transcription Factor/genetics ; TOR Serine-Threonine Kinases/genetics ; Vascular Endothelial Growth Factor A/genetics