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المؤلفون: Herath KB; Merck Research Laboratories, Rahway, NJ 07065, USA., Zhang C, Jayasuriya H, Ondeyka JG, Zink DL, Burgess B, Wang J, Singh SB

المصدر: Organic letters [Org Lett] 2008 May 01; Vol. 10 (9), pp. 1699-702. Date of Electronic Publication: 2008 Apr 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Adamantane/*chemistry , Aminobenzoates/*chemistry , Aminobutyrates/*chemical synthesis , Aminobutyrates/*chemistry , Aminophenols/*chemistry , Anilides/*chemistry , Anti-Bacterial Agents/*chemistry , Bridged-Ring Compounds/*chemical synthesis , Bridged-Ring Compounds/*chemistry , Polycyclic Compounds/*chemistry , Streptomyces/*metabolism, Adamantane/pharmacology ; Aminobenzoates/pharmacology ; Aminobutyrates/isolation & purification ; Aminobutyrates/pharmacology ; Aminophenols/metabolism ; Anilides/pharmacology ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Bacteria/metabolism ; Bridged-Ring Compounds/isolation & purification ; Bridged-Ring Compounds/pharmacology ; Microbial Sensitivity Tests ; Molecular Structure ; Polycyclic Compounds/metabolism ; Streptomyces/growth & development

المؤلفون: Singh SB; Merck Research Laboratories, Rahway, New Jersey 07065, USA. sheo_singh@merck.com, Zink DL, Huber J, Genilloud O, Salazar O, Diez MT, Basilio A, Vicente F, Byrne KM

المصدر: Organic letters [Org Lett] 2006 Nov 23; Vol. 8 (24), pp. 5449-52.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Bacterial Agents/*biosynthesis , DNA, Antisense/*genetics , Streptomyces/*genetics , Streptomyces/*metabolism, Anti-Bacterial Agents/pharmacology ; DNA, Bacterial/genetics ; Drug Design ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Microbial Sensitivity Tests ; Models, Molecular ; Spiro Compounds/pharmacology

المؤلفون: Singh SB; Merck Research Laboratories, RY80Y-355, P.O. Box 2000, Rahway, New Jersey 07065, USA. sheo_singh@merck.com, Zink DL, Liesch JM, Dombrowski AW, Darkin-Rattray SJ, Schmatz DM, Goetz MA

المصدر: Organic letters [Org Lett] 2001 Sep 06; Vol. 3 (18), pp. 2815-8.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Antiprotozoal Agents/*chemistry , Histone Deacetylases/*metabolism , Peptides, Cyclic/*chemistry, Amino Acid Substitution ; Animals ; Antiprotozoal Agents/pharmacology ; Eimeria tenella/drug effects ; Histone Deacetylase Inhibitors ; Magnetic Resonance Spectroscopy ; Molecular Conformation ; Parasitic Sensitivity Tests ; Peptides, Cyclic/pharmacology ; Proline/chemistry ; Sarcocystidae/drug effects ; Valine/chemistry

المؤلفون: Singh SB; Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065-0900, USA. sheo_singh@merck.com, Zink DL, Dombrowski AW, Dezeny G, Bills GF, Felix JP, Slaughter RS, Goetz MA

المصدر: Organic letters [Org Lett] 2001 Jan 25; Vol. 3 (2), pp. 247-50.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print Cited Medium: Print ISSN: 1523-7060 (Print) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Potassium Channel Blockers* , Potassium Channels* , Potassium Channels, Voltage-Gated*, Diterpenes/*chemical synthesis , Pyrones/*chemical synthesis, Animals ; CHO Cells ; Cricetinae ; Diterpenes/chemistry ; Diterpenes/pharmacology ; Fermentation ; Hypocreales/growth & development ; Immunosuppressive Agents/chemical synthesis ; Immunosuppressive Agents/chemistry ; Immunosuppressive Agents/pharmacology ; Kv1.1 Potassium Channel ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Molecular Conformation ; Pyrones/chemistry ; Pyrones/pharmacology ; Recombinant Proteins/antagonists & inhibitors