المؤلفون: Koppes EA; Division of Genetic and Genomic Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Johnson MA; Division of Genetic and Genomic Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America., Moresco JJ; Department of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, California, United States of America., Luppi P; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Lewis DW; Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Stolz DB; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Diedrich JK; Department of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, California, United States of America., Yates JR 3rd; Department of Molecular Medicine and Neurobiology, The Scripps Research Institute, La Jolla, California, United States of America., Wek RC; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America., Watkins SC; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Gollin SM; Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Park HJ; Department of Human Genetics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, United States of America., Drain P; Department of Cell Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America., Nicholls RD; Division of Genetic and Genomic Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

المصدر: PLoS genetics [PLoS Genet] 2023 Apr 17; Vol. 19 (4), pp. e1010710. Date of Electronic Publication: 2023 Apr 17 (Print Publication: 2023).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Prader-Willi Syndrome*/genetics , Prader-Willi Syndrome*/metabolism, Mice ; Animals ; Insulin Secretion/genetics ; Endoplasmic Reticulum Chaperone BiP ; Down-Regulation ; Proteomics ; Molecular Chaperones/genetics ; Molecular Chaperones/metabolism ; Insulin/genetics ; Insulin/metabolism ; Endoplasmic Reticulum/genetics ; Endoplasmic Reticulum/metabolism

المؤلفون: Raj D; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Podraza-Farhanieh A; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Gallego P; Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden., Kao G; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Naredi P; Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.; Department of Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden.

المصدر: PLoS genetics [PLoS Genet] 2022 Dec 08; Vol. 18 (12), pp. e1010538. Date of Electronic Publication: 2022 Dec 08 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2* , Caenorhabditis elegans Proteins*/genetics , Caenorhabditis elegans Proteins*/metabolism, Animals ; Caenorhabditis elegans/metabolism ; Cisplatin/pharmacology ; Insulin Secretion ; Mammals/metabolism ; Arsenite Transporting ATPases/chemistry ; Arsenite Transporting ATPases/genetics ; Arsenite Transporting ATPases/metabolism

المؤلفون: Ojima N; Division of Neurogenetics, Tohoku University Graduate School of Life Sciences, Sendai, Japan., Hara Y; Division of Neurogenetics, Tohoku University Graduate School of Life Sciences, Sendai, Japan.; Neuro-Network Evolution Project, Advanced ICT Research Institute, National Institute of Information and Communications Technology, Kobe, Japan., Ito H; Division of Neurogenetics, Tohoku University Graduate School of Life Sciences, Sendai, Japan., Yamamoto D; Division of Neurogenetics, Tohoku University Graduate School of Life Sciences, Sendai, Japan.; Neuro-Network Evolution Project, Advanced ICT Research Institute, National Institute of Information and Communications Technology, Kobe, Japan.

المصدر: PLoS genetics [PLoS Genet] 2018 Jun 11; Vol. 14 (6), pp. e1007434. Date of Electronic Publication: 2018 Jun 11 (Print Publication: 2018).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Corpora Allata/*metabolism , Drosophila Proteins/*metabolism , Drosophila melanogaster/*physiology , Juvenile Hormones/*biosynthesis , Reproduction/*genetics , Stress, Physiological/*genetics, Animals ; Brain/cytology ; Brain/metabolism ; Down-Regulation ; Drosophila Proteins/genetics ; Female ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/metabolism ; Juvenile Hormones/genetics ; Signal Transduction/genetics ; Up-Regulation

المؤلفون: Nowak C; Department of Medical Sciences and Science for Life Laboratory, Molecular Epidemiology Unit, Uppsala University, Uppsala, Sweden., Salihovic S; Department of Medical Sciences and Science for Life Laboratory, Molecular Epidemiology Unit, Uppsala University, Uppsala, Sweden., Ganna A; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, United States of America.; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA,United States of America.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, United States of America.; Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden., Brandmaier S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, München-Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, München-Neuherberg, Germany., Tukiainen T; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Broeckling CD; Proteomics and Metabolomics Facility, Colorado State University, Fort Collins, Colorado, United States of America., Magnusson PK; Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden., Prenni JE; Proteomics and Metabolomics Facility, Colorado State University, Fort Collins, Colorado, United States of America., Wang-Sattler R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, München-Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, München-Neuherberg, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, München-Neuherberg, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany.; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Giedraitis V; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Ärnlöv J; School of Health and Social Studies, Dalarna University, Falun, Sweden.; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Berne C; Department of Medical Sciences, Clinical Diabetology and Metabolism, Uppsala University, Uppsala, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, München-Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, München-Neuherberg, Germany.; German Center for Diabetes Research (DZD), München-Neuherberg, Germany., Ripatti S; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Public Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Wellcome Trust Sanger Institute, Hinxton, United Kingdom., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Pedersen NL; Department of Medical Epidemiology and Biostatistics (MEB), Karolinska Institutet, Stockholm, Sweden., Sundström J; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Ingelsson E; Department of Medical Sciences and Science for Life Laboratory, Molecular Epidemiology Unit, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States of America., Fall T; Department of Medical Sciences and Science for Life Laboratory, Molecular Epidemiology Unit, Uppsala University, Uppsala, Sweden.

المصدر: PLoS genetics [PLoS Genet] 2016 Oct 21; Vol. 12 (10), pp. e1006379. Date of Electronic Publication: 2016 Oct 21 (Print Publication: 2016).

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2/*genetics , Fatty Acids, Monounsaturated/*metabolism , Insulin/*genetics , Insulin Resistance/*genetics, Adult ; Aged ; Aged, 80 and over ; Bile Acids and Salts/metabolism ; Caffeine/metabolism ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/pathology ; Glucose/metabolism ; Glucose Tolerance Test ; Glycerophospholipids/metabolism ; Humans ; Insulin/blood ; Insulin/metabolism ; Insulin Secretion ; Male ; Metabolic Networks and Pathways/genetics ; Metabolomics ; Middle Aged ; Tyrosine/blood

المؤلفون: van de Bunt M; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Manning Fox JE; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Dai X; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Barrett A; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom., Grey C; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Li L; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., Bennett AJ; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom., Johnson PR; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom., Rajotte RV; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Surgery, University of Alberta, Edmonton, Alberta, Canada., Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Genetics, Stanford University, Stanford, California, United States of America., Dermitzakis ET; Department of Genetic Medicine and Development, University of Geneva, Geneva, Switzerland.; Institute for Genetics and Genomics in Geneva (iG3), University of Geneva, Geneva, Switzerland.; Swiss Institute of Bioinformatics, Geneva, Switzerland., MacDonald PE; Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada.; Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada., McCarthy MI; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom., Gloyn AL; Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom.

المصدر: PLoS genetics [PLoS Genet] 2015 Dec 01; Vol. 11 (12), pp. e1005694. Date of Electronic Publication: 2015 Dec 01 (Print Publication: 2015).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease*, Diabetes Mellitus, Type 2/*genetics , Insulin/*genetics , Transcription Factors/*genetics, Diabetes Mellitus, Type 2/pathology ; Exons ; Gene Expression Regulation ; Genome-Wide Association Study ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/pathology ; Quantitative Trait Loci/genetics ; Signal Transduction ; Transcription Factors/biosynthesis

المؤلفون: Kluth O; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Matzke D; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Kamitz A; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Jähnert M; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Vogel H; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany., Scherneck S; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Institute of Pharmacology and Toxicology, University of Braunschweig, Braunschweig, Germany., Schulze M; German Center for Diabetes Research (DZD), Neuherberg, Germany; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Staiger H; German Center for Diabetes Research (DZD), Neuherberg, Germany; Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany., Machicao F; German Center for Diabetes Research (DZD), Neuherberg, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany., Häring HU; German Center for Diabetes Research (DZD), Neuherberg, Germany; Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany; Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany., Joost HG; German Center for Diabetes Research (DZD), Neuherberg, Germany; Department of Pharmacology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Schürmann A; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany.

المصدر: PLoS genetics [PLoS Genet] 2015 Sep 08; Vol. 11 (9), pp. e1005506. Date of Electronic Publication: 2015 Sep 08 (Print Publication: 2015).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Cell Proliferation/*genetics , Diabetes Mellitus, Experimental/*genetics , Islets of Langerhans/*cytology, Animals ; Humans ; Insulin/metabolism ; Insulin Secretion ; Islets of Langerhans/metabolism ; Left-Right Determination Factors/genetics ; Mice ; Mice, Inbred C57BL ; Quantitative Trait Loci

المؤلفون: Olsson AH; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Volkov P; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Bacos K; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Dayeh T; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Hall E; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Nilsson EA; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Ladenvall C; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Rönn T; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden., Ling C; Department of Clinical Sciences, Epigenetics and Diabetes, Lund University Diabetes Centre, Clinical Research Centre, Malmö, Sweden.

المصدر: PLoS genetics [PLoS Genet] 2014 Nov 06; Vol. 10 (11), pp. e1004735. Date of Electronic Publication: 2014 Nov 06 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic* , Genome-Wide Association Study*, Diabetes Mellitus, Type 2/*genetics , Insulin/*genetics, DNA Methylation/genetics ; Diabetes Mellitus, Type 2/pathology ; Gene Expression Regulation ; Glutathione Peroxidase ; Glutathione Transferase ; Humans ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/metabolism ; Insulin-Secreting Cells/pathology ; Islets of Langerhans/pathology ; Peroxidases/genetics ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci/genetics ; RNA, Messenger/genetics ; Sorting Nexins/genetics

المؤلفون: Park S; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America., Alfa RW; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America; Neuroscience Program, Stanford University School of Medicine, Stanford, California, United States of America., Topper SM; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America., Kim GE; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America., Kockel L; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America., Kim SK; Department of Developmental Biology, Stanford University School of Medicine, Stanford, California, United States of America; Department of Medicine (Oncology Division) Stanford University School of Medicine, Stanford, California, United States of America; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California, United States of America.

المصدر: PLoS genetics [PLoS Genet] 2014 Aug 07; Vol. 10 (8), pp. e1004555. Date of Electronic Publication: 2014 Aug 07 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Type 2/*genetics , Drosophila Proteins/*genetics , Drosophila melanogaster/*genetics , Insulin/*metabolism, Animals ; Carrier Proteins/genetics ; DNA-Binding Proteins ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Drosophila Proteins/metabolism ; Drosophila melanogaster/metabolism ; Fasting ; Gene Knockdown Techniques ; Genome-Wide Association Study ; Humans ; Insulin/biosynthesis ; Insulin/genetics ; Insulin Resistance/genetics ; Insulin Secretion ; Neuropeptides ; Nuclear Proteins/genetics ; Repressor Proteins ; Signal Transduction/genetics ; Trans-Activators ; Transcription Factors/genetics

المؤلفون: Dayeh T; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Volkov P; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Salö S; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Hall E; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Nilsson E; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Olsson AH; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Kirkpatrick CL; Department of Cell Physiology and Metabolism, University Medical Center, Geneva, Switzerland., Wollheim CB; Department of Cell Physiology and Metabolism, University Medical Center, Geneva, Switzerland., Eliasson L; Islet Cell Exocytosis, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Rönn T; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Bacos K; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden., Ling C; Epigenetics and Diabetes, Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, CRC, Malmö, Sweden.

المصدر: PLoS genetics [PLoS Genet] 2014 Mar 06; Vol. 10 (3), pp. e1004160. Date of Electronic Publication: 2014 Mar 06 (Print Publication: 2014).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Epigenesis, Genetic*, DNA Methylation/*genetics , Diabetes Mellitus, Type 2/*genetics , Insulin/*genetics, CpG Islands/genetics ; Diabetes Mellitus, Type 2/metabolism ; Diabetes Mellitus, Type 2/pathology ; Disease Susceptibility ; Exocytosis/genetics ; Genome, Human ; Humans ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/metabolism ; Islets of Langerhans/pathology ; Promoter Regions, Genetic

المؤلفون: Bai H; Department of Ecology and Evolutionary Biology, Brown University, Providence, Rhode Island, United States of America., Kang P, Hernandez AM, Tatar M

المصدر: PLoS genetics [PLoS Genet] 2013 Nov; Vol. 9 (11), pp. e1003941. Date of Electronic Publication: 2013 Nov 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE

مواضيع طبية MeSH: Activins/*genetics , Drosophila Proteins/*genetics , Forkhead Transcription Factors/*genetics , Insulin/*genetics , Longevity/*genetics, Activins/metabolism ; Aging/genetics ; Aging/physiology ; Animals ; Carrier Proteins/genetics ; Carrier Proteins/metabolism ; Drosophila Proteins/metabolism ; Drosophila melanogaster/genetics ; Drosophila melanogaster/physiology ; Forkhead Transcription Factors/metabolism ; Humans ; Insulin/metabolism ; Insulin Secretion ; Longevity/physiology ; Signal Transduction