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المؤلفون: Brian J. Druker, Amie S. Corbin, Ian J. Griswold, Michael W. Deininger, Kara Johnson, Thomas O'Hare, Marc M. Loriaux
المصدر: PLoS ONE
PLoS ONE, Vol 4, Iss 10, p e7439 (2009)مصطلحات موضوعية: Pathology/Histopathology, Fusion Proteins, bcr-abl, lcsh:Medicine, Biology, SH2 domain, Cell Biology/Cell Signaling, 03 medical and health sciences, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, hemic and lymphatic diseases, STAT5 Transcription Factor, Oncology/Myeloproliferative Disorders, including Chronic Myeloid Leukemia, Animals, Proto-Oncogene Proteins c-cbl, Kinase activity, Phosphorylation, lcsh:Science, 030304 developmental biology, Adaptor Proteins, Signal Transducing, GRB2 Adaptor Protein, 0303 health sciences, Mice, Inbred BALB C, Multidisciplinary, Binding Sites, Leukemia, Hematology/Bone Marrow and Stem Cell Transplantation, lcsh:R, Signal transducing adaptor protein, Nuclear Proteins, Neoplasms, Experimental, Fusion protein, CRKL, Cell Transformation, Neoplastic, Hematology/Myeloproliferative Disorders, including Chronic Myeloid Leukemia, 030220 oncology & carcinogenesis, biology.protein, Cancer research, lcsh:Q, Female, Interleukin-3, GRB2, Signal transduction, Pathology/Hematology, Tyrosine kinase, Signal Transduction, Research Article
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المؤلفون: Meghan Ann Tucker, Joan MacNeill, Michael Heinrich, Steven P. Gygi, Yi Wang, Jianmin Ren, Judit Villén, Ting-Lei Gu, Roberto D. Polakiewicz, Jon M. Kornhauser, Julie Nardone, Brian J. Druker, Marc M. Loriaux, John Rush, Sean A. Beausoleil
المصدر: PLoS ONE
PLoS ONE, Vol 6, Iss 4, p e19169 (2011)مصطلحات موضوعية: Acute Myeloid Leukemia, Science, Bone Marrow Cells, Biology, Piperazines, Hematologic Cancers and Related Disorders, chemistry.chemical_compound, fluids and secretions, Cell Line, Tumor, hemic and lymphatic diseases, Stable isotope labeling by amino acids in cell culture, Leukemias, medicine, Humans, Phosphorylation, Phosphoamino Acids, Multidisciplinary, Cancers and Neoplasms, Myeloid leukemia, hemic and immune systems, Tyrosine phosphorylation, Hematology, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Acute Lymphoblastic Leukemia, medicine.disease, Leukemia, Myeloid, Acute, Leukemia, Oncology, fms-Like Tyrosine Kinase 3, chemistry, Mutation, embryonic structures, Immunology, Fms-Like Tyrosine Kinase 3, Quinazolines, Cancer research, Medicine, Signal transduction, Tyrosine kinase, Research Article, Signal Transduction
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3دورية أكاديمية
المؤلفون: Gu TL; Cell Signaling Technology, Inc., Danvers, Massachusetts, United States of America. tgu@cellsignal.com, Nardone J, Wang Y, Loriaux M, Villén J, Beausoleil S, Tucker M, Kornhauser J, Ren J, MacNeill J, Gygi SP, Druker BJ, Heinrich MC, Rush J, Polakiewicz RD
المصدر: PloS one [PLoS One] 2011 Apr 28; Vol. 6 (4), pp. e19169. Date of Electronic Publication: 2011 Apr 28.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
مواضيع طبية MeSH: Signal Transduction*/drug effects, Leukemia, Myeloid, Acute/*pathology , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology , fms-Like Tyrosine Kinase 3/*metabolism, Bone Marrow Cells/drug effects ; Bone Marrow Cells/metabolism ; Cell Line, Tumor ; Humans ; Mutation ; Phosphoamino Acids/metabolism ; Phosphorylation/drug effects ; Piperazines/pharmacology ; Quinazolines/pharmacology ; fms-Like Tyrosine Kinase 3/genetics
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4دورية أكاديمية
المؤلفون: Johnson KJ; Division of Hematology and Medical Oncology, Oregon Health & Science University Knight Cancer Institute, Portland, Oregon, United States of America. johnskar@ohsu.edu, Griswold IJ, O'Hare T, Corbin AS, Loriaux M, Deininger MW, Druker BJ
المصدر: PloS one [PLoS One] 2009 Oct 13; Vol. 4 (10), pp. e7439. Date of Electronic Publication: 2009 Oct 13.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
مواضيع طبية MeSH: Fusion Proteins, bcr-abl/*genetics , Leukemia/*genetics , Leukemia/*metabolism, Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Binding Sites ; Cell Transformation, Neoplastic ; Female ; GRB2 Adaptor Protein/metabolism ; Interleukin-3/metabolism ; Mice ; Mice, Inbred BALB C ; Neoplasms, Experimental/genetics ; Nuclear Proteins/metabolism ; Phosphatidylinositol 3-Kinases/metabolism ; Phosphorylation ; Proto-Oncogene Proteins c-cbl/metabolism ; STAT5 Transcription Factor/metabolism ; Signal Transduction