المؤلفون: Nakamura T; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA. tnakamura@scripps.edu slipton@scripps.edu.; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA., Oh CK; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA.; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA., Liao L; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA., Zhang X; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA.; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA., Lopez KM; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA., Gibbs D; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA., Deal AK; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA., Scott HR; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA., Spencer B; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA., Masliah E; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA., Rissman RA; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.; VA San Diego Healthcare System, San Diego, CA 92161, USA., Yates JR 3rd; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA., Lipton SA; Departments of Molecular Medicine and Neuroscience, and Neuroscience Translational Center, The Scripps Research Institute, La Jolla, CA 92037, USA. tnakamura@scripps.edu slipton@scripps.edu.; Neurodegenerative Disease Center, Scintillon Institute, San Diego, CA 92121, USA.; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA.

المصدر: Science (New York, N.Y.) [Science] 2021 Jan 15; Vol. 371 (6526). Date of Electronic Publication: 2020 Dec 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*enzymology , Cyclin-Dependent Kinase 5/*metabolism , Dynamins/*metabolism , Nitric Oxide/*metabolism , Nitric Oxide Synthase/*metabolism , Synapses/*enzymology, Alzheimer Disease/pathology ; Amyloid beta-Peptides/metabolism ; Animals ; Cysteine/genetics ; Cysteine/metabolism ; Disease Models, Animal ; HEK293 Cells ; Humans ; Mice ; Mice, Transgenic ; Mutation ; Nitroarginine/pharmacology ; Oxidation-Reduction ; Protein Processing, Post-Translational/drug effects ; Synapses/pathology ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/metabolism

المؤلفون: Cho DH; Center for Neuroscience, Aging, and Stem Cell Research, Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, Lipton SA

المصدر: Science (New York, N.Y.) [Science] 2009 Apr 03; Vol. 324 (5923), pp. 102-5.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Amyloid beta-Peptides/*metabolism , GTP Phosphohydrolases/*metabolism , Microtubule-Associated Proteins/*metabolism , Mitochondria/*ultrastructure , Mitochondrial Proteins/*metabolism , Neurons/*ultrastructure , Nitric Oxide/*metabolism, Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Amino Acid Motifs ; Amyloid beta-Peptides/pharmacology ; Animals ; Cell Line ; Cell Line, Tumor ; Cerebral Cortex/cytology ; Cysteine/analogs & derivatives ; Cysteine/genetics ; Cysteine/metabolism ; Cysteine/pharmacology ; Dynamins ; Female ; GTP Phosphohydrolases/chemistry ; Humans ; Male ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins/chemistry ; Mitochondria/drug effects ; Mitochondria/physiology ; Mitochondrial Proteins/chemistry ; Models, Molecular ; Mutation ; Neurons/drug effects ; Peptide Fragments/metabolism ; Peptide Fragments/pharmacology ; Protein Multimerization ; Protein Structure, Tertiary ; S-Nitrosothiols/pharmacology

المؤلفون: Lipton SA, Li H, Zaremba JD, McKercher SR, Cui J, Kang YJ, Nie Z, Soussou W, Talantova M, Okamoto S, Nakanishi N

المصدر: Science (New York, N.Y.) [Science] 2009 Jan 09; Vol. 323 (5911), pp. 208.

نوع المنشور: Comment; Letter

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Neurogenesis*, Autistic Disorder/*genetics , Autistic Disorder/*physiopathology , Myogenic Regulatory Factors/*genetics , Myogenic Regulatory Factors/*physiology , Neurons/*physiology, Animals ; Embryonic Stem Cells/physiology ; Gene Knockout Techniques ; MEF2 Transcription Factors ; Mice ; Mice, Knockout ; Neurons/cytology ; Phenotype ; Rett Syndrome/genetics ; Rett Syndrome/physiopathology ; Synapses/physiology

المؤلفون: Lipton SA; Center for Neuroscience and Aging, Burnham Institute, La Jolla, CA 92037, USA. slipton@burnham.org, Nakamura T, Yao D, Shi ZQ, Uehara T, Gu Z

المصدر: Science (New York, N.Y.) [Science] 2005 Jun 24; Vol. 308 (5730), pp. 1870; author reply 1870.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Nitric Oxide/*metabolism , Parkinson Disease/*metabolism , Ubiquitin/*metabolism , Ubiquitin-Protein Ligases/*metabolism, Animals ; Brain/metabolism ; Humans ; Lewy Bodies/metabolism ; Tissue Culture Techniques

المؤلفون: Gu Z; Center for Neuroscience and Aging, Program in Cell Adhesion and Extracellular Matrix Biology, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA., Kaul M, Yan B, Kridel SJ, Cui J, Strongin A, Smith JW, Liddington RC, Lipton SA

المصدر: Science (New York, N.Y.) [Science] 2002 Aug 16; Vol. 297 (5584), pp. 1186-90.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*, Brain Ischemia/*enzymology , Cerebral Cortex/*enzymology , Cysteine/*analogs & derivatives , Matrix Metalloproteinase 9/*metabolism , Neurons/*physiology , Phenylmercuric Acetate/*analogs & derivatives , S-Nitrosothiols/*metabolism, Animals ; Brain Ischemia/pathology ; Cell Line ; Cells, Cultured ; Cerebral Cortex/blood supply ; Cerebral Cortex/pathology ; Cysteine/metabolism ; Cysteine/pharmacology ; Enzyme Activation ; Enzyme Precursors/genetics ; Enzyme Precursors/metabolism ; Humans ; Matrix Metalloproteinase 9/chemistry ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Models, Molecular ; Nitric Oxide/metabolism ; Nitric Oxide Synthase/antagonists & inhibitors ; Nitric Oxide Synthase/metabolism ; Nitric Oxide Synthase Type I ; Oxidation-Reduction ; Phenylmercuric Acetate/pharmacology ; Rats ; Recombinant Proteins/metabolism ; Reperfusion ; S-Nitrosothiols/pharmacology ; Signal Transduction ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

المؤلفون: Lipton SA

المصدر: Science (New York, N.Y.) [Science] 1997 Jun 13; Vol. 276 (5319), pp. 1629-30.

نوع المنشور: Comment; Letter

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: AIDS Dementia Complex/*drug therapy , Anti-HIV Agents/*therapeutic use , Excitatory Amino Acid Antagonists/*therapeutic use , Memantine/*therapeutic use, Blood-Brain Barrier ; Clinical Trials as Topic ; Drug Therapy, Combination ; Humans ; Receptors, N-Methyl-D-Aspartate/antagonists & inhibitors

المؤلفون: Dreyer EB; Department of Neurology, Children's Hospital, Boston, MA., Kaiser PK, Offermann JT, Lipton SA

المصدر: Science (New York, N.Y.) [Science] 1990 Apr 20; Vol. 248 (4953), pp. 364-7.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Calcium/*metabolism , Calcium Channel Blockers/*pharmacology , HIV Envelope Protein gp120/*physiology , HIV-1/*analysis , Neurons/*drug effects, Animals ; Cells, Cultured ; HIV Envelope Protein gp120/administration & dosage ; HIV Envelope Protein gp120/antagonists & inhibitors ; Hippocampus/cytology ; Neurons/metabolism ; Nimodipine/pharmacology ; Rats ; Recombinant Proteins/pharmacology ; Retinal Ganglion Cells/drug effects ; Retinal Ganglion Cells/metabolism

المؤلفون: Leifer D, Lipton SA, Barnstable CJ, Masland RH

المصدر: Science (New York, N.Y.) [Science] 1984 Apr 20; Vol. 224 (4646), pp. 303-6.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Nerve Regeneration*, Antibodies, Monoclonal/*physiology , Antigens, Surface/*immunology , Isoantibodies/*physiology , Retina/*physiology , Retinal Ganglion Cells/*physiology, Animals ; Cell Adhesion ; Cells, Cultured ; Polylysine/pharmacology ; Rats ; Retina/cytology ; Thy-1 Antigens

المؤلفون: Lipton SA; Division of Neuroscience, Children's Hospital, Boston, MA 02115., Frosch MP, Phillips MD, Tauck DL, Aizenman E

المصدر: Science (New York, N.Y.) [Science] 1988 Mar 11; Vol. 239 (4845), pp. 1293-6.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Print ISSN: 0036-8075 (Print) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Atropine/*pharmacology , Mecamylamine/*pharmacology , Receptors, Nicotinic/*physiology , Retina/*cytology , Retinal Ganglion Cells/*cytology , Tubocurarine/*pharmacology, Animals ; Cells, Cultured ; Picrotoxin/pharmacology ; Rats ; Receptors, Nicotinic/drug effects ; Retinal Ganglion Cells/drug effects