المؤلفون: Banerjee N; Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0438., Wang H; Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0438., Wang G; Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0438., Khan MF; Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555-0438.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2020 May 01; Vol. 175 (1), pp. 64-74.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antioxidants/*pharmacology , Autoimmunity/*drug effects , Inflammation/*prevention & control , Isothiocyanates/*pharmacology , Kupffer Cells/*drug effects , NF-E2-Related Factor 2/*metabolism , Sulfoxides/*pharmacology , T-Lymphocytes/*drug effects, Acetates ; Animals ; Apoptosis/drug effects ; Female ; Heme Oxygenase-1/metabolism ; Humans ; Inflammation/chemically induced ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation Mediators/metabolism ; Jurkat Cells ; Kupffer Cells/immunology ; Kupffer Cells/metabolism ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred MRL lpr ; NF-E2-Related Factor 2/genetics ; Oxidative Stress/drug effects ; Phosphorylation ; Signal Transduction ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; Transcription Factor RelA/metabolism ; Trichloroethylene

المؤلفون: Weaver JL; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland., Zadrozny LM; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland., Gabrielson K; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland.; Department of Molecular and Comparative Pathobiology, Johns Hopkins University, Baltimore, Maryland., Semple KM; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland.; Division of Gastroenterology and Inborn Errors Products, Office of Drug Evaluation III, Office of New Drugs, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland., Shea KI; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland., Howard KE; Division of Applied Regulatory Science, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, U.S. Food & Drug Administration, Silver Spring, Maryland.

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2019 May 01; Vol. 169 (1), pp. 194-208.

نوع المنشور: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Immunological/*toxicity , Immune System/*drug effects , Lymphocyte Activation/*drug effects , Nivolumab/*toxicity , Programmed Cell Death 1 Receptor/*antagonists & inhibitors , T-Lymphocytes/*drug effects, Animals ; Bone Marrow Transplantation ; Female ; Genotype ; Humans ; Immune System/immunology ; Immune System/metabolism ; Immune System/pathology ; Liver Transplantation ; Mice, Inbred NOD ; Mice, Transgenic ; Programmed Cell Death 1 Receptor/immunology ; Programmed Cell Death 1 Receptor/metabolism ; Signal Transduction ; Species Specificity ; T-Lymphocytes/immunology ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Thymus Gland/immunology ; Thymus Gland/transplantation

المؤلفون: Fang X; Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100190, China., Zhang L, Feng Y, Zhao Y, Dai J

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2008 Oct; Vol. 105 (2), pp. 312-21. Date of Electronic Publication: 2008 Jun 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Environmental Pollutants/*toxicity , Fluorocarbons/*toxicity , Immunity, Cellular/*drug effects , Immunity, Innate/*drug effects , Spleen/*drug effects , T-Lymphocytes/*drug effects , Thymus Gland/*drug effects, Adrenocorticotropic Hormone/blood ; Animals ; Antigens, CD/analysis ; Apoptosis/drug effects ; Body Weight/drug effects ; Cell Cycle/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Hydrocortisone/blood ; Hypothalamo-Hypophyseal System/drug effects ; Hypothalamo-Hypophyseal System/metabolism ; Interferon-gamma/metabolism ; Interleukin-1beta/metabolism ; Interleukin-4/metabolism ; Male ; Mice ; Mice, Inbred BALB C ; NF-kappa B/metabolism ; PPAR alpha/genetics ; PPAR alpha/metabolism ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Pituitary-Adrenal System/drug effects ; Pituitary-Adrenal System/metabolism ; RNA, Messenger/metabolism ; Spleen/immunology ; Spleen/pathology ; T-Lymphocytes/immunology ; T-Lymphocytes/pathology ; Thymus Gland/immunology ; Thymus Gland/pathology ; Time Factors

المؤلفون: Borchers MT; Division of Environmental Genetics and Molecular Toxicology, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0056, USA. michael.borchers@uc.edu, Wesselkamper SC, Eppert BL, Motz GT, Sartor MA, Tomlinson CR, Medvedovic M, Tichelaar JW

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2008 Sep; Vol. 105 (1), pp. 188-99. Date of Electronic Publication: 2008 May 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Acrolein/*toxicity , Lung/*drug effects , Receptors, Antigen, T-Cell, alpha-beta/*physiology , Receptors, Antigen, T-Cell, gamma-delta/*physiology , T-Lymphocytes/*physiology, Animals ; Apoptosis/drug effects ; Cell Separation ; Epithelial Cells/drug effects ; Epithelial Cells/pathology ; Gene Expression Profiling ; Interleukin-18/physiology ; Lung/immunology ; Lung/pathology ; Macrophages/drug effects ; Macrophages/physiology ; Mice ; Mice, Inbred C57BL ; Mucin 5AC ; Mucins/analysis ; Oligonucleotide Array Sequence Analysis

المؤلفون: Lewis TL; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, Morgantown, West Viginia 26506, USA., Brundage KM, Brundage RA, Barnett JB

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2008 May; Vol. 103 (1), pp. 97-107. Date of Electronic Publication: 2008 Feb 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Anilides/*toxicity , Calcium/*metabolism , Homeostasis/*drug effects , Lymphocyte Activation/*drug effects , T-Lymphocytes/*drug effects, Animals ; Cell Nucleus/drug effects ; Cell Nucleus/metabolism ; Female ; Humans ; Interleukin-2/metabolism ; Jurkat Cells ; Membrane Potentials/drug effects ; Mice ; Mice, Inbred BALB C ; NFATC Transcription Factors/metabolism ; Protein Transport ; Spectrometry, Fluorescence ; T-Lymphocytes/metabolism ; Thapsigargin/pharmacology

المؤلفون: Mitchell LA; College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131-0001, USA., Gao J, Wal RV, Gigliotti A, Burchiel SW, McDonald JD

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2007 Nov; Vol. 100 (1), pp. 203-14. Date of Electronic Publication: 2007 Jul 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Inhalation Exposure*, Immune System/*drug effects , Lung/*drug effects , Lymphocyte Activation/*drug effects , Nanotubes, Carbon/*toxicity , T-Lymphocytes/*drug effects, Aerosols ; Animals ; Bronchoalveolar Lavage Fluid/cytology ; Cells, Cultured ; Dose-Response Relationship, Drug ; Gene Expression Regulation/drug effects ; Immune System/metabolism ; Immune System/pathology ; Interleukin-10/metabolism ; Interleukin-6/metabolism ; Killer Cells, Natural/drug effects ; Leukocyte Count ; Lung/metabolism ; Lung/pathology ; Macrophages, Alveolar/drug effects ; Macrophages, Alveolar/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; NAD(P)H Dehydrogenase (Quinone) ; NADPH Dehydrogenase/metabolism ; Oxidative Stress/drug effects ; Particle Size ; RNA, Messenger/metabolism ; Spleen/drug effects ; Spleen/metabolism ; T-Lymphocytes/metabolism ; T-Lymphocytes/pathology ; Time Factors

المؤلفون: Fisher MT; Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia 23113, USA., Nagarkatti M, Nagarkatti PS

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2004 Mar; Vol. 78 (1), pp. 116-24. Date of Electronic Publication: 2004 Jan 12.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*physiology , DNA, Complementary/*biosynthesis , Environmental Pollutants/*toxicity , Gene Expression/*drug effects , Polychlorinated Dibenzodioxins/*toxicity , Promoter Regions, Genetic/*genetics , T-Lymphocytes/*drug effects, Animals ; Cell Cycle/drug effects ; Cell Cycle/genetics ; Chromatin/genetics ; DNA, Complementary/genetics ; Female ; Genes, bcl-2/genetics ; Inhibitor of Apoptosis Proteins ; Ligands ; Mice ; Mice, Inbred C57BL ; Oligonucleotide Array Sequence Analysis ; Precipitin Tests ; Proteins/genetics ; RNA, Messenger/biosynthesis ; Receptors, Aryl Hydrocarbon/drug effects ; Receptors, Aryl Hydrocarbon/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Thymus Gland/cytology ; Thymus Gland/drug effects

المؤلفون: Camacho IA; Department of Microbiology and Immunology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia 23298, USA., Nagarkatti M, Nagarkatti PS

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2004 Mar; Vol. 78 (1), pp. 96-106. Date of Electronic Publication: 2004 Jan 12.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*drug effects , Polychlorinated Dibenzodioxins/*toxicity , T-Lymphocytes/*drug effects , Teratogens/*toxicity , Thymus Gland/*cytology , Thymus Gland/*embryology, Animals ; Apoptosis/genetics ; CD8-Positive T-Lymphocytes/physiology ; Caspase 3 ; Caspases/metabolism ; Cell Separation ; DNA Primers ; Female ; Gene Expression Regulation/drug effects ; In Situ Nick-End Labeling ; Mice ; Mice, Inbred C57BL ; Phenotype ; Pregnancy ; Reverse Transcriptase Polymerase Chain Reaction ; Signal Transduction/drug effects

المؤلفون: Yang HM; National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, West Virginia 26505, USA., Butterworth L, Munson AE, Meade BJ

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2003 Feb; Vol. 71 (2), pp. 207-16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Immunosuppression Therapy*, Immunoglobulin M/*biosynthesis , Spleen/*drug effects , T-Lymphocytes/*drug effects , Vehicle Emissions/*toxicity, Adjuvants, Immunologic ; Animals ; Cell Division/drug effects ; Dose-Response Relationship, Drug ; Female ; Inhalation Exposure ; Intubation, Intratracheal ; Lung/drug effects ; Lung/pathology ; Mice ; Mice, Inbred Strains ; Organ Size/drug effects ; Spleen/immunology ; T-Lymphocytes/immunology

المؤلفون: Do Y; Department of Microbiology and Immunology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia 23298-0613, USA., Ryu S, Nagarkatti M, Nagarkatti PS

المصدر: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2002 Nov; Vol. 70 (1), pp. 63-72.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Print ISSN: 1096-6080 (Print) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*drug effects , Estradiol/*analogs & derivatives , Estradiol/*toxicity , Membrane Glycoproteins/*genetics , T-Lymphocytes/*immunology , Thymus Gland/*drug effects , fas Receptor/*genetics, Animals ; Apoptosis/genetics ; Apoptosis/immunology ; Atrophy/chemically induced ; Caspase 8 ; Caspase 9 ; Caspase Inhibitors ; Cell Count ; Cell Division/drug effects ; Enterotoxins/immunology ; Enzyme Inhibitors/pharmacology ; Fas Ligand Protein ; Female ; Gene Expression Regulation ; Lymphocyte Activation/immunology ; Membrane Glycoproteins/deficiency ; Membrane Glycoproteins/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Mutant Strains ; Oligonucleotide Array Sequence Analysis ; T-Lymphocytes/cytology ; Thymus Gland/immunology ; Thymus Gland/pathology ; Up-Regulation ; fas Receptor/immunology