المؤلفون: Isabel Silva, Nuno Vale, Henrique Reguengo, Diana Duarte, Filipa Amaro, José Carlos Oliveira, Paula Fresco, Dany Silva, Jorge Gonçalves

المساهمون: Instituto de Investigação e Inovação em Saúde

المصدر: Biomolecules, Vol 9, Iss 9, p 409 (2019)
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP
Biomolecules
Volume 9
Issue 9

مصطلحات موضوعية: 0301 basic medicine, Indoles, Skin Neoplasms, Cell Survival / drug effects, Indoles / analysis, Metabolite, lcsh:QR1-502, MCF-7 cell line, Breast Neoplasms / metabolism, Biochemistry, lcsh:Microbiology, Kynureninase, chemistry.chemical_compound, 0302 clinical medicine, Melanoma / pathology, Melanoma, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Aromatic L-amino acid decarboxylase, Indoles / metabolism, Skin Neoplasms / metabolism, Carbidopa / pharmacology, indole-3-acetonitrile, 030220 oncology & carcinogenesis, Carbidopa, Breast Neoplasms / pathology, Female, medicine.drug, Spectrometry, Mass, Electrospray Ionization, Cell Survival, Breast Neoplasms, Article, A375 cell line, Tryptophan / metabolism, 03 medical and health sciences, Breast cancer, Cell Line, Tumor, medicine, Humans, tryptophan, carbidopa, Molecular Biology, Cell Proliferation, Skin Neoplasms / pathology, Tryptophan, medicine.disease, Melanoma / metabolism, nervous system diseases, 030104 developmental biology, Enzyme, chemistry, Cancer research, Cell Proliferation / drug effects

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9138061437389dba5962460c6c79f056
https://www.mdpi.com/2218-273X/9/9/409

المؤلفون: Piotr Dziunycz, Karine Lefort, Xunwei Wu, G. Paolo Dotto, Sungeun Chang, Bach-Cuc Nguyen, Yang Sui Brooks, Günther F.L. Hofbauer

المساهمون: University of Zurich

المصدر: Nature
Nature, vol. 465, no. 7296, pp. 368-372

مصطلحات موضوعية: Keratinocytes, p53, Skin Neoplasms, Mice, SCID, Mice, 0302 clinical medicine, Mice, Inbred NOD, Cyclosporin a, ATF3, Cells, Cultured, Cellular Senescence, 0303 health sciences, Multidisciplinary, Melanoma, Calcineurin, 10177 Dermatology Clinic, NFAT, 3. Good health, Gene Expression Regulation, Neoplastic, Cell Transformation, Neoplastic, calcineurin/NFAT, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, Cancer Stem cells, Carcinoma, Squamous Cell, Cell aging, Signal Transduction, Activating Transcription Factor 3/metabolism, Animals, Calcineurin/deficiency, Calcineurin/genetics, Calcineurin/metabolism, Calcineurin Inhibitors, Carcinoma, Squamous Cell/chemically induced, Carcinoma, Squamous Cell/metabolism, Carcinoma, Squamous Cell/pathology, Cell Line, Tumor, Cell Proliferation, Cell Transformation, Neoplastic/genetics, Cell Transformation, Neoplastic/metabolism, Cyclosporine/pharmacology, Humans, Keratinocytes/metabolism, Keratinocytes/pathology, NFATC Transcription Factors/antagonists & inhibitors, NFATC Transcription Factors/deficiency, NFATC Transcription Factors/genetics, NFATC Transcription Factors/metabolism, Neoplasm Transplantation, Skin Neoplasms/chemically induced, Skin Neoplasms/metabolism, Skin Neoplasms/pathology, Tumor Suppressor Protein p53/metabolism, 610 Medicine & health, Biology, Article, 03 medical and health sciences, medicine, Squamous Cell Carcinoma, cyclosporine, 030304 developmental biology, 1000 Multidisciplinary, Activating Transcription Factor 3, NFATC Transcription Factors, medicine.disease, Cancer cell, Cancer research, Skin cancer, Tumor Suppressor Protein p53

وصف الملف: Wu_X_et_al_Nature_2010_V.pdf - application/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c401cd0f52ac396b891110f36c4b6f36
https://doi.org/10.5167/uzh-41832

المؤلفون: Erwan Le Scolan, Alain Mauviel, Delphine Javelaud, Vasileia I. Alexaki, Léon C van Kempen, Kunxin Luo

المساهمون: Signalisation normale et pathologique de l'embryon aux thérapies innovantes des cancers, Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Radboud University Medical Center [Nijmegen], Department of Molecular & Cell Biology [Berkeley], University of California [Berkeley], University of California-University of California, This work was supported by the Donation Henriette et Emile Goutière, Institut National du Cancer (INCa, PLBIO 08-0126 ), Cancéropôle Ile-de- France, INSERM, CNRS, Ligue Nationale Contre le Cancer (Comité des Yvelines), and Université Paris XI (to A.M.), and by funds from NIH RO1 CA101891 (to K.L.). V.I.A. was the recipient of a Cancéropôle Ile-de-France/ Région Ile-de-France post-doctoral fellowship., University of California [Berkeley] (UC Berkeley), University of California (UC)-University of California (UC), BMC, Ed.

المصدر: Molecular Cancer
Molecular Cancer, BioMed Central, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 2011, 10 (1), pp.2. ⟨10.1186/1476-4598-10-2⟩
Molecular Cancer, 10:2. BMC
Molecular Cancer, Vol 10, Iss 1, p 2 (2011)

مصطلحات موضوعية: Cancer Research, Skin Neoplasms, Leupeptins, Nude, Skin Neoplasms/metabolism, Smad Proteins, SMAD, Mice, 0302 clinical medicine, Transforming Growth Factor beta, MESH: Up-Regulation, MESH: Animals, Neoplasm Metastasis, Smad Proteins/metabolism, Melanoma, 0303 health sciences, Tumor, MESH: Proteasome Endopeptidase Complex, Cyclin-Dependent Kinase Inhibitor p21/genetics, Intracellular Signaling Peptides and Proteins, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 3. Good health, Up-Regulation, DNA-Binding Proteins, Intracellular Signaling Peptides and Proteins/metabolism, Oncology, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, [SDV.BBM.GTP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], Molecular Medicine, RNA Interference, Proteasome Inhibitors, Transforming Growth Factor beta/metabolism, Cyclin-Dependent Kinase Inhibitor p21, Transcriptional Activation, MESH: Cell Line, Tumor, MESH: Melanoma, MESH: RNA Interference, Mice, Nude, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, lcsh:RC254-282, Cell Line, MESH: Cyclin-Dependent Kinase Inhibitor p21, 03 medical and health sciences, Downregulation and upregulation, [SDV.CAN] Life Sciences [q-bio]/Cancer, Melanoma/metabolism, Cell Line, Tumor, Proto-Oncogene Proteins, MESH: Cell Proliferation, MESH: Intracellular Signaling Peptides and Proteins, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], medicine, MESH: Mice, Nude, Animals, Humans, Neoplasm Invasiveness, Leupeptins/pharmacology, Autocrine signalling, MESH: Mice, MESH: Transforming Growth Factor beta, 030304 developmental biology, Cell Proliferation, MESH: Humans, Cell growth, Research, MESH: Skin Neoplasms, SKI protein, MESH: Smad Proteins, MESH: Leupeptins, Transforming growth factor beta, MESH: Neoplasm Invasiveness, medicine.disease, MESH: Neoplasm Metastasis, MESH: Gene Knockdown Techniques, MESH: Cell Line, MESH: Proto-Oncogene Proteins, Proto-Oncogene Proteins/genetics, Cancer cell, Cancer research, biology.protein, MESH: Transcriptional Activation, human activities, DNA-Binding Proteins/genetics, Neoplasm Transplantation, MESH: Neoplasm Transplantation, MESH: DNA-Binding Proteins

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb74f62e5e96127a24e2466f4ff6a9a6